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Synthesis and Preliminary Pharmacological Evaluation of New Analogues of Diclofenac as Potential Anti-inflammatory Agents
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         A group of amine derivatives [4-aminobenzenesulfonamide derivatives, 2-aminopyridine and 2-aminothiazole] incorporated to α-carbon of diclofenac a well known non-steroidal anti-inflammatory drug (NSAID) to increase bulkiness were designed and synthesized for evaluation as  a potential anti-inflammatory agents with expected COX-2 selectivity. In vivo acute anti-inflammatory activity of the selected final compounds (9, 12 and 13) was evaluated in rats using egg-white induced edema model of inflammation in a dose equivalent to (3 mg/Kg) of diclofenac sodium. All tested compounds  produced a significant reduction  in paw edema with respect to the effect of propylene glycol 50% v/v (control group). Moreover, the 4-aminobenzenesulfonamide derivative (compound 9) exhibited superior anti-inflammatory activity compared to diclofenac sodium at times 180-300 minutes with the same onset of action. The results of this study indicate that the incorporation of the selected aromatic amino groups in to diclofenac maintain its anti-inflammatory activity.                                                                                                                             

Key words: amine derivatives, anti-inflammatory, diclofenac derivatives, COX-2 selectivity.                                                                                                 

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Publication Date
Mon Oct 01 2018
Journal Name
Journal Of Craniofacial Surgery
Evaluation the Efficacy of Hilotherm Cooling System in Reducing Postoperative Pain and Edema in Maxillofacial Traumatized Patients and Orthognathic Surgeries
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Publication Date
Thu Oct 20 2022
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Evaluation of Insulin Resistance and Glutathione-S-transferase in Iraqi Patients with Type 2 Diabetes Mellitus and Diabetic Peripheral Neuropathy
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Diabetes mellitus type 2 (T2DM) is a metabolic disorder that influences above 450 million individuals around the world. Type 2 diabetes is a lack of insulin due to pancreatic β-cell malfunction and insulin resistance. This study aimed to detect insulin resistance using homeostasis model assessment (HOMA IR) and determined the correlation with glutathione-s-transferase (GST) activity in T2DM and neuropathy patients as a predictor of oxidative stress, which occurs when the oxidation-antioxidant equilibrium is disrupted. Reactive oxygen species causes vascular injury and a series of inflammation. In the present study, the results show there is no significant difference in diabetic patients (DM) and neuropathy patients (NU) versus healthy p

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Publication Date
Sun Apr 01 2018
Journal Name
Journal Of Engineering And Applied Sciences
New Data Security Method Based on Biometrics
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Merging biometrics with cryptography has become more familiar and a great scientific field was born for researchers. Biometrics adds distinctive property to the security systems, due biometrics is unique and individual features for every person. In this study, a new method is presented for ciphering data based on fingerprint features. This research is done by addressing plaintext message based on positions of extracted minutiae from fingerprint into a generated random text file regardless the size of data. The proposed method can be explained in three scenarios. In the first scenario the message was used inside random text directly at positions of minutiae in the second scenario the message was encrypted with a choosen word before ciphering

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Publication Date
Tue Feb 01 2022
Journal Name
Iraqi Journal Of Science
New Root-based Stemmer for Arabic Language
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Importance of Arabic language stemming algorithm is not less than that of other languages stemming in Information Retrieval (IR) field. Lots of algorithms for finding the Arabic root are available and they are mainly categorized under two approaches which are light (stem)-based approach and root-based approach. The latter approach is somehow better than the first approach. A new root-based stemmer is proposed and its performance is compared with Khoja stemmer which is the most efficient root-based stemmers. The accuracy ratio of the proposed stemmer is (99.7) with a difference (1.9) with Khoja stemmer.

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Publication Date
Sat Sep 01 2012
Journal Name
Journal Of Economics And Administrative Sciences
New Approach for Solving Multi – Objective Problems
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  There are many researches deals with constructing an efficient solutions for real problem having Multi - objective confronted with each others. In this paper we construct a decision for Multi – objectives based on building a mathematical model formulating a unique objective function by combining the confronted objectives functions. Also we are presented some theories concerning this problem. Areal application problem has been presented to show the efficiency of the performance of our model and the method. Finally we obtained some results by randomly generating some problems.

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Publication Date
Wed Feb 16 2022
Journal Name
Iraqi Journal Of Science
New Arabic Stemming based on Arabic Patterns
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Algorithms for Arabic stemming available in two main types which are root-based approach and stem-based approach. Both types have problems which have been solved in the proposed stemmer which combined rules of both main types and based on Arabic patterns (Tafealat1) to find the added letters. The proposed stemmer achieved root exploration ratio (99.08) and fault ratio (0.9).

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Publication Date
Wed Aug 30 2023
Journal Name
Iraqi Journal Of Science
New Approach for Calculate Exponential Integral Function
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     This manuscript presents a new approach to accurately calculating exponential integral function that arises in many applications such as contamination, groundwater flow, hydrological problems and mathematical physics. The calculation is obtained with easily computed components without any restrictive assumptions

     A detailed comparison of the execution times is performed. The calculated results by the suggested approach are better and faster accuracy convergence than those calculated by other methods. Error analysis of the calculations is studied using the absolute error and high convergence is achieved. The suggested approach out-performs all previous methods  used to calculate this function and this decision is

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Publication Date
Fri Jan 01 2016
Journal Name
Bulletin Of Mathematics And Statistics Research
New Approximation Operators Using Mixed Degree Systems
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This paper is concerned with introducing and studying the first new approximation operators using mixed degree system and second new approximation operators using mixed degree system which are the core concept in this paper. In addition, the approximations of graphs using the operators first lower and first upper are accurate then the approximations obtained by using the operators second lower and second upper sincefirst accuracy less then second accuracy. For this reason, we study in detail the properties of second lower and second upper in this paper. Furthermore, we summarize the results for the properties of approximation operators second lower and second upper when the graph G is arbitrary, serial 1, serial 2, reflexive, symmetric, tra

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Publication Date
Fri Jan 01 2016
Journal Name
Modern Applied Science
New Combined Technique for Fingerprint Image Enhancement
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This paper presents a combination of enhancement techniques for fingerprint images affected by different type of noise. These techniques were applied to improve image quality and come up with an acceptable image contrast. The proposed method included five different enhancement techniques: Normalization, Histogram Equalization, Binarization, Skeletonization and Fusion. The Normalization process standardized the pixel intensity which facilitated the processing of subsequent image enhancement stages. Subsequently, the Histogram Equalization technique increased the contrast of the images. Furthermore, the Binarization and Skeletonization techniques were implemented to differentiate between the ridge and valley structures and to obtain one

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Publication Date
Tue Aug 15 2023
Journal Name
Al-academy
The new aesthetic in contemporary world painting
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The research tagged: the new aesthetic in contemporary world painting. The research contained five chapters. The first chapter dealt with the research problem and its importance. It dealt with the concept of the new aesthetic as a concept concerned with the topics of the mind, i.e. the most comprehensive and diverse topics. The New Aesthetic is an aesthetic and stylistic structure whose taste, aesthetic, artistic and emotional contribute to its structure with awareness of the context. The aim of the research is to identify the new aesthetic in contemporary world painting. As for the objective limits of the research, the researcher was interested in studying the new aesthetic, especially in abstract expressionism, pop art, opera, and conc

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