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Controlled Release Floating Matrix Tablet of Captopril
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The present study was done to prepare a gastroretentive floating tablet of captopril (CAP) which is an angiotensin converting enzyme inhibitor (ACE-inhibitor) used in the treatment of hypertension and heart failure. CAP is mainly absorbed from the proximal intestine and to a lesser extent from the stomach, also CAP stability decreases as the pH raised above 1.2 and this makes it a suitable candidate for floating dosage form.Effervescent floating tablets of CAP were prepared in order to prolong the gastric residence time and increase the bioavailability of the drug. The floating tablets of CAP were prepared by direct compression and wet granulation technique, using the polymer hydroxypropylmethylcellulose (HPMC) as the primary retarding polymer together with carboxymethylcellulose(CMC) ,ethyl cellulose(EC) and pectin as a secondary release modifying polymers in different ratios of (1:1, 3:1 and 9:1). Different formulation parameters were studied such as type of diluents, amount of effervescent agent, methods of preparation and their effects on buoyancy and the in vitro drug release profile as well as their physical characteristics. The wet granulation method shows a good flow and compressibility characteristics and a better dose uniformity in comparison with direct compression technique. Pectin together with HPMC in the ratio of 1:1 was found to meet the requirement for a good matrix formation and floating characteristics and the drug release was sufficiently sustained for 12 h with floating time >24h and floating lag time of 2 min. Kinetic modeling of the release data for the selected formula showed that the mechanism of drug release pattern follows anomalous or non –fickian diffusion.

Key words: Captopril, floating, matrix tablet, pectin.

 

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Publication Date
Wed May 03 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Security of Iris Recognition and Voice Recognition Techniques
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  Recently, biometric technologies are used widely due to their improved security that decreases cases of deception and theft. The biometric technologies use physical features and characters in the identification of individuals. The most common biometric technologies are: Iris, voice, fingerprint, handwriting and hand print. In this paper, two biometric recognition technologies are analyzed and compared, which are the iris and sound recognition techniques. The iris recognition technique recognizes persons by analyzing the main patterns in the iris structure, while the sound recognition technique identifies individuals depending on their unique voice characteristics or as called voice print. The comparison results show that the resul

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Publication Date
Thu Aug 17 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Application of Kass' Snake in Medical Images Segmentation
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A   snake   is   an   energy-minimizing   spline   guided   by   external

constraint forces and influenced by image forces that pull it toward features such as lines and edges. Snakes are active contour models: they lock onto nearby edges, localizing them accurately. Snakes provide a unified account of a number of visual problems, including detection of edges, lines, and motion tracking. We have used snakes successfully for segmentation, in  which  user-imposed  constraint forces guide the snake near features of interest (anatomical structures). Magnetic Resonance Image (MRI) data set and Ultrasound images are used for our experiments.

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Publication Date
Wed Apr 26 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Synthesis And Characterization Of Some 1,3,4 - Thiadiazole Derivatives
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  A series of N- benzoyl  - 2 – alkyl -1- ( 2- thio – 1,3,4- thiadiazole -5- yl ) , have been synthesized from DL- α– amino acids , The methyl and sulfon thio ethers of these compounds were also prepared , representative samples of the prepared compounds were characterized from their IR- spectrum and elemental analysis .
 

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Publication Date
Mon Jul 31 2017
Journal Name
Journal Of Engineering
Production of Biofuels from Selected Cellulosic Waste materials
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Publication Date
Tue Apr 01 2008
Journal Name
Journal Of The Faculty Of Medicine Baghdad
immunomodulation of echinococcosis with estrogen progesterone and HCGL
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Background: Echinococcosis is a zoonotic disease with high incidence.

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Publication Date
Fri Jan 10 2020
Journal Name
Journal Of Legal Sciences
The impact of sex change on status matters
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When a person responds to the temptation of Satan and changes his sex from male to female or vice versa, it will be terrible, He is neither male nor female; Because this change will be apparent only and will not affect the person,

This change if it occurs has implications impaction Bor personal status issues.

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Publication Date
Wed Apr 01 2015
Journal Name
Journal Of Engineering
Software Implementation of Binary BCH Decoder Using Microcontroller
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In this paper a decoder of binary BCH code is implemented using a PIC microcontroller for code length n=127 bits with multiple error correction capability, the results are presented for correcting errors up to 13 errors. The Berkelam-Massey decoding algorithm was chosen for its efficiency. The microcontroller PIC18f45k22 was chosen for the implementation and programmed using assembly language to achieve highest performance. This makes the BCH decoder implementable as a low cost module that can be used as a part of larger systems. The performance evaluation is presented in terms of total number of instructions and the bit rate.

 

 

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Publication Date
Sat Sep 30 2017
Journal Name
College Of Islamic Sciences
The small provisions of his upbringing and manners
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Praise be to Allah, Lord of the Worlds, and peace and blessings be upon our master Muhammad and his good and pure family. At the end of this research, we summarize some of the most important findings of our research, namely:
Raising a child properly from childhood leads to integrity in the life of the individual society, and if the young raised bad education, this education will affect itself and society negatively, so on parents and government institutions in any country to take care of children, and Islamic countries Specifically to give the child great attention; he is raised on the Koran and watered from its fountains, and armed with a weapon of morality from a young age, and to understand the biography of Mustafa (peace be upon h

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Publication Date
Tue Mar 26 2019
Journal Name
Iraqi Journal Of Science
Biosynthesis of Iron Oxide Nanoparticles Using Escherichia coli
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This study proposed to synthesize iron oxide by biological method nanoparticles. The E.coli is used to reduce Ferric chloride salt into iron particles. The formation of iron oxide nanoparticle was initially monitored by visual observation and then characterized with the help of various characterization techniques such as Uv-vis spectroscopy, (AFM) and (FTIR) analysis, which revealed that the biosynthesized iron oxide nanoparticles were spherical within size 27.7 nm. Optimization of iron oxide nanoparticle biosynthesis by E.coli was performed for parameters (temperature and pH) and the results revealed that temperature 37°C and pH 5 were the optimum conditions for iron oxide nanoparticales biosynthesis by E.coli.<

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Publication Date
Wed Mar 10 2021
Journal Name
Baghdad Science Journal
Family preference for the presence of cortical yellow
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The population density of the insect on Alorat and fruits located in the lower part of the tree more than the middle part of the plant and insect in one place and demonstrates that there is a nest there were conducted laboratory and field studies on citrus Hsasahanwaa and the Alvdaúaa distribution of cortical insect yellow ....

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