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Possible Cardiac Adverse Effects Induced by Therapeutic Doses of Ciprofloxacin in Juvenile Rats
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Ciprofloxacin is widely used in treating adults infected with Gram-negative bacteria. It is contraindicated in children, growing adolescents and during pregnancy due to joint toxicity. Its toxicity concerning other organs needs to be clarified. Thus, this study was designed to study the possible cardiac damage induced by two selected doses of ciprofloxacin in juvenile rats.Eighteenth healthy juvenile rats (4 weeks old and their weight 30 ± 2 gm) were utilized in this study and divided into three groups. Group-I control; group II and group III, respectively injected IP with 25 mg/kg and 50 mg/kg ciprofloxacin every 12 hours for one week. Serum enzymes activities alanine aminotransferase (ALT), aspartate aminotransferase  (AST), creatin kinase -muscle brain isoform (CK-MB), and lactate dehydrogenase (LDH) were assessed. Histological examination of heart tissues was also performed. The results of this study showed that, ALT, AST and CK-MB enzymes were significantly elevated only in group III compared to control. LDH enzyme was elevated in both group II and III. Concerning histological examination of the heart's gross sections, the results obtained from this work demonstrated the degeneration and necrosis in the hearts of group II and III juvenile rats compared to control animals. In conclusion, our results showed that the selected therapeutic doses of ciprofloxacin utilized in this study caused cardiac damage in juvenile rats.

Key words: Fluoroquinolones, cardiac adverse effects, juvenile rat .

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Publication Date
Sun Dec 15 2019
Journal Name
Journal Of Baghdad College Of Dentistry
The Effects of Nano Alumina On Mechanical Properties of Room Temperature Vulcanized Maxillofacial Silicone (Pilot Study)
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Background: Facial disfigurement can be the result of a congenital anomaly, trauma or tumor surgery, in many cases the prosthetic rehabilitation is indicated. Maxillofacial prosthetic materials should have desirable and ideal physical, aesthetic, and biological properties and those properties should be kept for long period of time in order to reach patient acceptance. Silicone elastomer are the most commonly used material for facial restoration because of its favorable properties mechanically and physically as the biocompatibility and good elasticity. Aim of this study: This study aimed to evaluate the effect of addition of Aluminum oxide (Al2O3) Nano fillers in different concentrations on tear strength and hardness of VST 50F room tempe

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Publication Date
Sun Jul 30 2023
Journal Name
Iraqi Journal Of Science
A Mathematical Modelling of a Plant-Herbivore Community with Additional Effects of Food on the Environment
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     By taking into account various food components in the ecosystem, the research intends to develop a set of difference equations to simulate a plant-herbivore interaction of Holling Type II. We determine the local stability of the equilibrium points for the scenarios of extinction, semi-extinction (extinction for one species), and coexistence using the Linearized Stability Theorem. For a suitable Lyapunov function, we investigate theoretical findings to determine the global stability of the coexisting equilibrium point. It is clear that the system exhibits both Flip and Neimark-Sacker bifurcation under particular circumstances using the central manifold theorem and the bifurcation theory. Numerical simulations are

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Publication Date
Fri Nov 22 2019
Journal Name
Chalcogenide Letters
CONCENTRATION EFFECTS ON ELECTRONIC AND SPECTROSCOPIC PROPERTIES OF ZnCdS WURTZOIDS: A DENSITY FUNCTIONAL THEORY STUDY
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Publication Date
Wed May 13 2009
Journal Name
Journal Of Planner And Development
Urban creep on the green areas and its environmental effects on the city of Baghdad
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he planning process is generally aimed at developing the city and making it meet the needs of different citizens. The green areas constitute one of the basic needs of the city and with the rapid and unusual growth in the size of cities, especially in the third world countries, which is often embodied in capitals. Which was achieved as a result of many reasons, including political, economic and social and even enshrined through some of the decisions that were issued and the city of Baghdad, but a clear example of these cities. The city and the environment are inseparable terms. The city is where people spend their lives and their daily experiences, and the environment is the center in w

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Publication Date
Tue Jun 01 2021
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Relationships of Osmolality and Oxidative Stress with Semen Quality and Their Effects on Male Fertility
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The objective of this study was to investigate and find the relationships between human semen osmolality and oxidative stress with semen quality. Semen analysis was determined to evaluate semen quality and fertility. The concentration of semen malondialdehyde (MDA) was measured to assess oxidative stress. For this purpose, one hundred seventy healthy adult males were used in this study. The study was conducted from September 2018 to November 2019 in the Infertility care and in vitro fertilization center (IVF) and the Biology department of the College of Science at Salahaddin University in Erbil city. A significant positive correlation was observed between the total sperm motility, grade activity, and sperm motility index with semen osmol

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Publication Date
Tue Jan 01 2019
Journal Name
Progress In Industrial Ecology, An International Journal
The effects of copper additives on the glass transition temperature and hardness for epoxy resin
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Publication Date
Sat Jul 31 2021
Journal Name
Iraqi Journal Of Science
Computer Simulation for the Effects of Optical Aberrations on Solar Images Using Karhunen-Loeve polynomials
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     Numerical simulations were carried out to evaluate the effects of different aberrations modes on the performance of optical system, when observing and imaging the solar surface. Karhunen-Loeve aberrations modes were simulated as a wave front error in the aperture function of the optical system. To identify and apply the appropriate rectification that removes or reduces various types of aberration, their attribute must be firstly determined and quantitatively described. Wave aberration function is well suitable for this purpose because it fully characterizes the progressive effect of the optical system on the wave front passing through the aperture. The Karhunen-Loeve polynomials for circular aperture were used to

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Publication Date
Sun Jan 30 2022
Journal Name
Iraqi Journal Of Science
Biochemical Tests as an Indicator for the Effects of Electrical Generator Exhausts on Human Health
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       Diesel generators are used in various locations throughout Baghdad city, central Iraq, when the public electricity  power is in outage. The main purpose of the current research is to investigate possible changes in certain biochemical parameters in the blood of operators of diesel generators in different locations Baghdad city, at both Rusafa and Karkh sides. The workers were divided according to the number of working years.

       Serum urea, creatinine, alkaline phosphatase (AlP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), albumin, total serum bilirubin (TSB), and glomerular filtration rate (GFR) were analyzed in samples from forty wo

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Publication Date
Tue Jan 25 2022
Journal Name
Iraqi Journal Of Science
Estimation the best areas of Sun duration hours in Iraq by applying IDW type of interpolation techniques by using GIS program
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In this paper solar radiation was studied over the Iraqi countary land. The best sun duration hours regions (maximum hours) in Iraq were estimated detected by using Geographic information system (GIS Ver. 9.2) program to apply the (Inverse distance weighting) IDW exact interpolation technique depending on the measured data of metrological stations were distributed on the land areas of Iraq. The total area of the best regions was calculated .Excel 2007 program is used in calculation, graphics and comparison the results.

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Publication Date
Sat Oct 30 2021
Journal Name
Iraqi Journal Of Science
Theoretical Investigation of the Effects of some Geometrical Parameters on the Performance of Wire-Plate Electrostatic Precipitator
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     Some geometric parameters affecting the performance of a wire-plate electrostatic precipitator (ESP) are investigated theoretically. A numerical model was built to investigate the influence of the discharge wire size, wire separation, collector plates spacing, and roughness factor on the ESP performance. The results show that thinner wires emit higher current than larger ones at the same applied voltage, which would be suitable for low voltage power supply to generate the desired current density at the collecting electrodes. The results also show that, as the discharge electrodes get closer, the corona gets suppressed, resulting in a diminished corona current flow. On the other hand, as the distance between elect

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