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The Correlation Between Hyperglycemia and Rheumatoid Factor in Type 2 Diabetic Patients in Al- Risafa Area, Baghdad
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Diabetes mellitus type 2 (T2DM) formerly called non-insulin dependent diabetes mellitus (NIDDM) or adult-onset diabetes is a common disease. Rheumatoid factor is a well-established test used in the diagnosis and follows the prognosis of rheumatoid arthritis (RA). Rheumatoid factor is sometimes found in serum of patients with other diseases including diabetes mellitus (DM), due to the presence of pro-inflammatory cytokines such as TNF- α which play an important role in chronic inflammatory and autoimmune diseases like rheumatoid arthritis (RA). The aim of the study is to investigate the associations between type 2 diabetes mellitus (T2DM) and rheumatoid arthritis (RA) in scope of rheumatoid factor (RF), hyperglycemia and body mass index (BMI), in patients with T2DM lived in Al-Risafa area -Baghdad. One hundred twenty five (125) type 2 diabetes mellitus (T2DM) patients were selected from the out patients department of the Specialized Center for Endocrinology and Diabetes, Baghdad; in addition to (70) apparently healthy non diabetic, non arthritic subjects as control, during the period from Sep. - Dec./2010. The ages of both patients and control subjects were within (35-75) years. This study focus to search for the correlation between T2DM and RF "qualitative and quantitative" in relation to body mass index (BMI) and gender. Out of 125 DM-patients (73 female and 52 male), 44 (35.2 %) showed positive RF when compared with healthy controls (N=3, 4.3%). [P value =0.01 is significant] with female dominance (N=28, 63.6%) in compared to males (N=16, 36.4 %), when these diabetics with RF positive were titered for RF (8, 16, 32 and 64 IU/ml), the following results were obtained. The highest percentage of titer observed with 34.1% in those with RF titer 64 IU/ ml [P value = 0.01] when compared with healthy control.  18.2 % had RF titer of 8 IU/ ml, 20.4 % had RF titer of 16 IU/ ml, 27.3 % had RF titer of 32 IU/ ml and 34.1 % had RF titer of 64 IU/ ml. The highest percentage among the overweight, DM patients (38.9 %) have a mean titer 64 IU/ml, a percentage decrease respectively as below: 38.9 % had RF titer of 64 IU/ ml, 27.8% had RF titer of 32 IU/ ml, 16.6 % had RF titer 16 IU / ml and 16.6% had RF titer 8 IU/ ml. The highest number and percentage of DM with RF positive (N=17, 38.6 %) were located among higher age (50-59), (60-69) & (70 -79) year groups (N=17, 38.6%), (N=13, 29.5%) & (N=8, 18.2%) respectively, [P- Value < 0.01] when compared to the corresponding controls. The effect of fasting plasma glucose level of type 2 DM in patients who have RF positive titer, is found that > 7.2 mmol/l glucose in plasma contribute the highest titer (N=28, 63.6 %), in comparison with group of plasma glucose levels < 7.2 mmol/l patients (N=16, 36.4%). with a highly significant difference, P-value = 0.006.Smokers diabetic patients with RF positive (N=27, 61.4%) dominate over non- smokers with RF positive (N=17, 38.6%). The results of this study indicate that there is a reasonable increased frequency of positive rheumatoid factor (RF) in type 2 diabetic patients. Poor glycemic control is associated with higher RF titer in positive cases. The titer of T2DM smoker patients is associated with positive RF values that exceed the titer of the non- smoker RF positive patients. Thus, smoking might not be correlated significantly to DM, but may contribute to its complications.

Key words: T2DM, RF, BMI, Smoking.

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Publication Date
Mon Mar 01 2021
Journal Name
Desalination And Water Treatment
Extraction model to remove antibiotics from aqueous solution by emulsion and Pickering emulsion liquid membrane
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Publication Date
Fri Mar 01 2024
Journal Name
Baghdad Science Journal
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Tue Nov 01 2022
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Tue Jun 01 2021
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Mesoporous Silica Nanoparticles as a System for Ciprofloxacin Drug Delivery; Kinetic of Adsorption and Releasing
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Mesoporous silica (MPS) nanoparticle was prepared as carriers for drug delivery systems by sol–gel method from sodium silicate as inexpensive precursor of silica and Cocamidopropyl betaine (CABP) as template. The silica particles were characterized by SEM, TEM, AFM, XRD, and N2adsorption–desorption isotherms. The results show that the MPS particle in the nanorange (40-80 nm ) with average diameter equal to 62.15 nm has  rods particle morphology, specific surface area is 1096.122 m2/g, pore volume 0.900 cm3/g, with average pore diameter 2.902 nm, which can serve as efficient carriers for drugs. The adsorption kinetic of Ciprofloxacin (CIP) drug was studied and the data were analyzed and found to match well with

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Publication Date
Mon Mar 11 2019
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A Spectral, Optical, Microscopic Study, Synthesis and Characterization of PVC Films Containing Schiff Base Complexes
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In this work, synthesis of conducting polymeric films namely, PVC thin films was carried out containing Schiff base (L) with Cu2+, Cr3+, Ni2+, Co2+, in addition to inspecting the possibilities of measuring energy gap values of PVC-L-M with variety metal ions. These new polymeric films (PVC-L-M) were characterized by FTIR spectrophotometry, energy gap and surface morphology. The optical data recorded that the band gap values are influenced by the type of metals. All modified films have a red shift in optical properties in the ultraviolet region. The PVC-L-Co(II) was the lowest value of the optical band gap, 3.1 eV.

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Publication Date
Wed Dec 30 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Preparation, Characterization and Ex vivo Permeability Study of Transdermal Apixaban O/W Nanoemulsion Based Gel
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This study designed to prepare ultrafine apixaban (APX) o/w nanoemulsion (NE) based gel with droplet size below 50 nm as a good method for transdermal APX delivery without using permeation enhancer, alternatively, the formulation components itself act as permeation enhancer. APX, a potent oral anticoagulant drug that selectively and directly inhibit coagulation factor Xa, was selected as a good candidate for transdermal delivery as it displays poor water solubility (0.028 mg/mL) and low bioavailability (50%). APX-NE gel was prepared using triacetin, triton-x-100 and carbitol as oil phase, surfactant and cosurfactant respectively, while Carbopol 940 used as a gelling agent. Ex vivo permeation of APX-NE gel through human stratum c

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Wed Feb 06 2019
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Fri May 05 2023
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Publication Date
Sat May 30 2020
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Neuroquantology
Synthesis and Study NiO Charactrization of Extract from Green Tea Plant Prepared by Chemical Method
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