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bijps-391
Preparation and Evaluation of Meloxicam Microsponges as Transdermal Delivery System

The aim of present study was to develop gel formulation of microsponges of poorly soluble drug meloxicam (MLX) in order to enhance the release and dissolution of MLX which is the limitation for preparation in topical forms. Also skin delivery is an alternative administration for MLX that can minimize gastrointestinal (GI) side effects and improve patient compliance. The microsponges of MLX were prepared by quasi-emulsion solvent diffusion method.  The effects of drug:polymer ratio, stirring time and Eudragit polymer type on the physical characteristics of microsponges were investigated and characterized for production yield, loading efficiency, particle size, surface morphology, and in vitro drug release from microsponges. The selected microsponge formula was incorporated into gel. The prepared microsponge gel was evaluated as visual inspection, pH, spreadability, viscosity, in addition to in vitro drug release. The results showed that the microsponge formula with Eudragit L100 polymer had optimum physical properties and enhanced the dissolution and release of MLX when compared with other formulas and pure drug. MLX microsponge carbopol gel produced a significant (p<0.05) improvement of the in vitro release than pure MLX gel. Hence quasi emulsion solvent diffusion method was a promising method to produce MLX microsponges with markedly enhanced dissolution rate.

 Keywords: Meloxicam, Microsponges, Gel.

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Publication Date
Mon Apr 01 2019
Journal Name
Plant Archives
Association between BTN1A1 gene polymorphism and some reproductive efficiency indicator and heat toleranceinholsteincows

This study was conducted in Al-Salam station for Dairy cattle/private sector, for the period from 1-11-2016 to 1-11-2017, to determine the association between BTN1A1 gene polymorphism and reproductive efficiency indicator and heat tolerance in 50 Holstein cows. The results of BTN1A1 gene analysis showed a highly significant Different (P<0.01) between genotypes of BTN1A1 gene’s genotypes AA, AB the percentage were 72.00, 28.00 % respectively. Results showed that services per conception and days open was significantly (P<0.05) affected by polymorphism of BTN1A1 gene and for cows with AA genotype, there was also a significant difference (P<0.05) between the genotypes of BTN1A1 gene for IgG concentration in calves blood who belong to mother

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Publication Date
Wed Nov 02 2022
Journal Name
Annals Of Forest Research
Publication Date
Wed Mar 30 2022
Journal Name
Iraqi Journal Of Science
Matter Density Distributions and Reaction Cross Sections for 8Li and 22N Exotic Nuclei

     The Harmonic Oscillator (HO) and Gaussian (GS) wave functions within the Binary Cluster Model (BCM) were employed to investigate neutron, proton and matter densities of the ground state as well as the elastic proton form factors of one neutron 8Li and 22N halo nuclei. The long tail is a property that is clearly shown in the neutron density. The existence of a long tail in the neutron densities of 8Li and 22N indicates that these nuclei have a neutron halo structure. Moreover, the matter rms radii and the reaction cross section  of these nuclei were calculated using the Glauber model.

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Publication Date
Sun May 01 2016
Journal Name
Iosr Journal Of Computer Engineering
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Publication Date
Wed Mar 30 2022
Journal Name
Iraqi Journal Of Science
Crawling and Mining the Dark Web: A Survey on Existing and New Approaches

    The last two decades have seen a marked increase in the illegal activities on the Dark Web. Prompt evolvement and use of sophisticated protocols make it difficult for security agencies to identify and investigate these activities by conventional methods. Moreover, tracing criminals and terrorists poses a great challenge keeping in mind that cybercrimes are no less serious than real life crimes. At the same time, computer security societies and law enforcement pay a great deal of attention on detecting and monitoring illegal sites on the Dark Web. Retrieval of relevant information is not an easy task because of vastness and ever-changing nature of the Dark Web; as a result, web crawlers play a vital role in achieving this task. The

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Publication Date
Tue Mar 01 2011
Journal Name
Journal Of Economics And Administrative Sciences
Developing and Sustaining a Multilevel Competitive Learning Organization – A Behavioral and Cognitive Approach

To maintain a sustained competitive position in the contemporary environment of  knowledge  economy,  organizations  as an open social systems must have an ability to learn and know  how to adapt to rapid changes  in a proper fashion so that organizational objectives will be achieved efficiently and effectively.  A multilevel approach is adopted proposing that organizational learning suffers from the lack of interest about the strategic competitive performance of the organization. This remains implicit almost in all models of organizational learning and there is little focus on how learning organizations achieve sustainable competitive advantage . A dynamic model that captures t

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Publication Date
Tue Sep 15 2020
Journal Name
Al-academy
Communication and Outreach and their Relation to Industrial Product Circulation: حنان غازي صالح

  With the increase of the huge developments that the world witnesses day after day, the contemporary designer tried to reveal his abilities in development and coping with transitions in all types of design discourses such as the functional and technical discourses, and the numerous means of communications included in these discourses and their influence over the recipient, because they carry perceptible, tangible or implicit vocabulary that influences the recipient's relation with the circulation of the industrial product through the effectiveness of numerous means of communication contained in the design products represented by the functional, formal, aesthetic, and technical communication. In order to highlight the importance of

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Publication Date
Fri Sep 02 2022
Journal Name
Journal Of Legal Sciences
Overlap and integration between the competent anti-corruption bodies and other regulatory bodies

The protection of public money and its surrounding with special provisions that guarantee that protection from every legal or material assault by the supervisory bodies competent to combat corruption are described as a criminal procedural protection aimed at prosecuting criminals in general crimes and government corruption crimes in particular, and working to recover funds and return them to the state treasury, These agencies operate in an integrated format, each other and in a coherent manner with each other, in order to achieve the purpose of their establishment and reach the basic goal, which is to eliminate corruption from the theoretical side Practical reality.

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Publication Date
Tue Dec 24 2019
Journal Name
Journal Of Legal Sciences
Economic Duress and its Effect to the Contract under English and Iraqi Law

English law, unlike many Anglo-Saxon laws, has adopted the doctrine of economic duress delayed. Under this doctrine, the contractor who has entered into a contract as a result of an unlawful pressure that threatens his financial or commercial interests may rescind the contract on the grounds that the contract was concluded under economic duress which make the contact voidable. More than forty years have passed since the adoption the economic duress doctrine in English law, however, there are still some issues remain controversial. Is the Lawful Act duress economic duress?

Iraqi Civil Law did not explicitly regulate the doctrine of economic duress. However, the Iraqi authors when explain the rules of duress under this law indicate

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Publication Date
Wed Feb 08 2023
Journal Name
Iraqi Journal Of Science
Hybrid Fuzzy Logic and Artificial Bee Colony Algorithm for Intrusion Detection and Classification

In recent years, with the growing size and the importance of computer networks, it is very necessary to provide adequate protection for users data from snooping through the use of one of the protection techniques: encryption, firewall and intrusion detection systems etc. Intrusion detection systems is considered one of the most important components in the computer networks that deal with Network security problems. In this research, we suggested the intrusion detection and classification system through merging Fuzzy logic and Artificial Bee Colony Algorithm. Fuzzy logic has been used to build a classifier which has the ability to distinguish between the behavior of the normal user and behavior of the intruder. The artificial bee colony al

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