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Formulation and Evaluation of Ezetimibe Nanoparticles
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The aim of this study is to formulate and evaluate ezetimibe nanoparticles using solvent antisolvent technology. Ezetimibe is a practically water-insoluble drug which acts as a lipid lowering drug that selectively inhibits the intestinal absorption of cholesterol and related phytosterols. Ezetimibe prepared as nano particles in order to improve its solubility and dissolution rate.

Thirty formulas were prepared and different stabilizing agents were used with different concentrations such as poly vinyl pyrrolidone (PVPK-30), poly vinyl alcohol (PVA), hydroxy propyl methyl cellulose E5 (HPMC), and poloxamer. The ratios of drug to stabilizers used to prepare the nanoparticles were 1: 2, 1:3 and 1:4.

The prepared nanoparticles were evaluated for particle size, entrapment efficiency, dissolution study, Fourier transform infrared spectroscopy, differential scanning calorimetry, and atomic force microscopy. The percentage of drug entrapment efficiency of F1-F30 was ranged from 85% ± 1 to 98 % ± 1. On the other hand dissolution rate increasing as the particle surface area is increase due to reduction of particle size to the nano range.

The results showed that poly vinyl pyrrolidone (PVPK-30) was found to be the best stabilizer.

 Keywords: Ezetimibe, Nanoparticles, Particle Size, poly vinyl alcohol.

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Publication Date
Wed Jun 01 2022
Journal Name
V. International Scientific Congress Of Pure, Applied And Technological Sciences
Lightweight Image Compression Using Polynomial and Transform Coding
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Publication Date
Wed Jun 30 2021
Journal Name
Modern Sport
Leadership theories in management and psychologist educational filed
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All domains in this world built based on set of theories. Those theories have been responsible for interpretation of some phenomena and interlocking relationships around us. Commonly, theories are categorized by which aspect is believed. Also,can find a group of theories produced regardingto the leadership domain. This paper will be presented some of these theories like (Great Man Theory, Trait Theory, Behavioral Theories, Contingency Theories, Situational Theory, Transactional Theories, and Transformational Theories). where these theories considered the most popular and common in the field of leader and will be discussed by this work

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Publication Date
Fri Jan 01 2021
Journal Name
International Journal Of Agricultural And Statistical Sciences
STATISTICAL COMPUTATION AND APPLICATION WITH GENERALIZED POISSON DISTRIBUTION
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Scopus
Publication Date
Tue Jan 29 2019
Journal Name
Journal Of The College Of Education For Women
Personality Type and its Relationship with Withdrawal Observer
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The current research was aimed at the following:
1. Measurement of Personality Type Observer of the University students.
2. Identify the differences in Personality Type Observer among the University students according to variable of Sex (male / female). And according to variable of Specialization (scientific / literary)
3. Measurement of Withdrawal of the University students.
4. Identify the differences in Withdrawal among the University students according to variable of Sex (male / female). And according to variable of Specialization (scientific / literary).
5. Identify the relationship between Personality Type Observer and Withdrawal.
To achieve this aims of the research, the researchers set up the instrument is scale

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Publication Date
Tue Jan 01 2019
Journal Name
Open Access Journal Of Chemistry
Gas Storage and Separation in Metal Organic Frameworks
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Publication Date
Sat Jan 01 2011
Journal Name
Al- Mustansiriya J. Sci
Rationally Extending Modules and Strongly Quasi-Monoform Modules
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An R-module M is called rationally extending if each submodule of M is rational in a direct summand of M. In this paper we study this class of modules which is contained in the class of extending modules, Also we consider the class of strongly quasi-monoform modules, an R-module M is called strongly quasi-monoform if every nonzero proper submodule of M is quasi-invertible relative to some direct summand of M. Conditions are investigated to identify between these classes. Several properties are considered for such modules

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Publication Date
Tue Jul 15 2025
Journal Name
Journal Of Engineering
Aerodynamic Characteristics Comparison between Spiroid and Blended Winglets
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A numerical and experimentally investigation for two types of winglets (spiroid and blended), which are used to reduce the induced drag caused by the trailing vortices were presented and discussed in this work. The SOLIDWORK 2016 was used to model a rectangular wing geometry of NACA2415 cross-sectional airfoil with blended and spiroid airfoils (2415 and 0012). The steady, incompressible N.S equations with standard (

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Publication Date
Tue Jan 01 2013
Journal Name
Mathematical Theory And Modeling
Fibrewise Near Compact and Locally Near Compact Spaces
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In this paper we define and study new concepts of fibrewise topological spaces over B namely, fibrewise near compact and fibrewise locally near compact spaces, which are generalizations of well-known concepts near compact and locally near compact topological spaces. Moreover, we study relationships between fibrewise near compact (resp., fibrewise locally near compact) spaces and some fibrewise near separation axioms.

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Publication Date
Tue Jan 09 2024
Journal Name
Nigerian Journal Of Parasitology
Toxoplasmosis and Metabolic Disorders among Children with Autism.
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Publication Date
Tue Nov 30 2021
Journal Name
Journal Of The Indonesian Mathematical Society
e*-Hollow-Lifting and Cofinitely e*-Lifting Modules
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