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Design, Synthesis and Kinetic Study of Coumarin-Based Mutual Prodrug of 5-Fluorouracil and Dichloroacetic acid
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On the basis of known coumarin-based prodrug system, a novel coumarin-based mutual prodrug of 5-fluorouracil and dichloroacetic acid was designed, synthesized and evaluated as a promising oral chemotherapeutic agent basing on in vitro stability study in HCl buffer (pH 1.2) and in phosphate buffer (pH 7.4), as well as in vitro release study in human serum. The chemical structure of prodrug was confirmed by analyzing its FTIR, 1H NMR, 13C NMR and MS-ESI spectra. The results of in vitro kinetic study indicated that the prodrug was significantly stable in HCl and in phosphate buffers, and was hydrolyzed in human serum followed pseudo first order kinetics.

Keywords: Coumarin-based prodrug, 5-fluorouracil, Dichloroacetate, kinetics.

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Publication Date
Mon Mar 08 2021
Journal Name
Baghdad Science Journal
fabrication and study the characteristic of PbTelSi
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In this research has been the manufacture and study the properties of the solar cell type retail hybrid manner thermal evaporation emptiness were studying the properties of the cell at room temperature showed measurements stream circuit behavior linear cell manufacturers reached were calculated efficiency tool cell manufacturers, as well as the expense of workers filling the cell

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Publication Date
Fri Mar 31 2017
Journal Name
Journal Of Engineering
Cultivation of Chlorella Vulgaris Using Airlift Photobioreactor Sparged with 5%CO 2 -Air as a Biofixing Process
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The present paper addresses cultivation of Chlorella vulgaris microalgae using airlift photobioreactor that sparged with 5% CO 2 /air. The experimental data were compared with that obtained from bioreactor aerated with air and unsparged bioreactor. The results showed that the concentration of biomass is 0.36 g l -1  in sparged bioreactor with CO2/air, while, the concentration of biomass reached to 0.069 g l -1  in the unsparged bioreactor. They showed also that aerated  ioreactor.with CO2/air gives more biomass production even the bioreactor was aerated with air. This study proved that application of sparging system for  ultivation of Chlorella vulgaris microalgae using either CO2/air mixture or air has a significant

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Publication Date
Sat Jan 01 2022
Journal Name
Food Science And Technology
Study on herbicide residues in soybean processing based on UPLC-MS/MS detection
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Publication Date
Mon Mar 08 2021
Journal Name
Baghdad Science Journal
The role of sialic acid in the immune response of patients with acute leukemia Almufaawi the subject and is on treatment Alkamiawi this
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The focus of this research revolves around the importance level of sialic acid in the reasoning of cases, including tumors and then evaluate the patient's response to treatment and its impact on the immune response there are a lot of evidence showing that parts Alkrbu ???????? in peptides sugary and glycoproteins play an important role in Alfalitin life and responsiveness

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Publication Date
Thu Mar 30 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
The Relationship between Uric Acid Concentration and Some of Plasma Lipids in Patients with C. V. Disease in General Hospital of Al-Nasseriya
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         Cardiovascular disorders  are  refer to the class of diseases that involve the heart or blood vessels (arteries and veins). While the term technically refers to any disease that affects the cardiovascular system. Cholesterol is classified as a sterol (a contraction of steroid and

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Publication Date
Tue Feb 26 2019
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
Use the Style of the Activity Based Cost time Drivine (TDABC) and its Impact on the Untapped Resources: Empirical study in the General Company for Textile Industries - Wasit
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   The research aims to identify the importance of using the style of the cost on the basis of activity -oriented in time TDABC and its role in determining the cost of products more equitably and thus its impact on the policy of allocation of resources through the reverse of the changes that occur on an ongoing basis in the specification of the products and thus the change in the nature and type of operations . The research was conducted at the General Company for Textile Industries Wasit / knitting socks factory was based on research into the hypothesis main of that ( possible to calculate the cost of activities that cause the production through the time it takes to run these activities can then be re- distributed product cost

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Publication Date
Thu Apr 01 2010
Journal Name
Ibn Al-haitham Journal For Pure And Applied Science
The Invariant Moments Based With Wavelet Used To Decide the Authintication and Originality of Images
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Publication Date
Wed Nov 01 2017
Journal Name
Journal Of Engineering
Performance Evaluation of Sequencing Batch Reactor and Conventional Wastewater Treatment Plant based on Reliability assessment
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Baghdad city has been faced numerous issues related to freshwater environment deteriorations due to many reasons, mainly was the discharge of wastewater without adequate treatment. Al-Rustamiya Wastewater Treatment Plant (WWTP) have been constructed among many plants in Baghdad city to reduce the amount of wastewater discharged into natural environment and its subsequent adverse effects. This study was conducted to evaluate the performance of the plant which consist of a conventional activated sludge (CAS) and sequencing batch reactors (SBR) systems as secondary treatment units and its ability to meet Iraqi specifications. A reliability level determination and analysis also were conducted to find the plant's stability an

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Publication Date
Sat Dec 30 2023
Journal Name
Iraqi Journal Of Science
Automatic Segmentation and Identification of Abnormal Breast Region in Mammogram Images Based on Statistical Features
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Breast cancer is one of the most common malignant diseases among women;
Mammography is at present one of the available method for early detection of
abnormalities which is related to breast cancer. There are different lesions that are
breast cancer characteristic such as masses and calcifications which can be detected
trough this technique. This paper proposes a computer aided diagnostic system for
the extraction of features like masses and calcifications lesions in mammograms for
early detection of breast cancer. The proposed technique is based on a two-step
procedure: (a) unsupervised segmentation method includes two stages performed
using the minimum distance (MD) criterion, (b) feature extraction based on Gray

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Publication Date
Wed Feb 16 2022
Journal Name
Iraqi Journal Of Science
Efficient method to Recognition of Anemia Images based on Moment Invariants and Decision tree classifier
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Anemia is one of the common types of blood diseases, it lead to lack of number of RBCs (Red Blood Cell) and amount hemoglobin level in the blood is lower than normal.
In this paper a new algorithm is presented to recognize Anemia in digital images based on moment variant. The algorithm is accomplished using the following phases: preprocessing, segmentation, feature extraction and classification (using Decision Tree), the extracted features that are used for classification are Moment Invariant and Geometric Feature.
The Best obtained classification rates was 84% is obtained when using Moment Invariants features and 74 % is obtained when using Geometric Feature. Results indicate that the proposed algorithm is very effective in detect

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