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Protective Effect of Daidzein on Ifosfamide-Induced Neurotoxicity Via Improving Some Selected Oxidative Stress Parameters in Male Rats
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  In this study, the possible protective effects of daidzein on ifosfamide-induced neurotoxicity in male rats were examined by the determination of changes in selected oxidant–antioxidant markers of male rats’ brain tissue.

Twenty-eight (28) apparently-healthy Wistar male rats weighing (120-150gm) allocated into 4 groups (n=7) were used in this study. Rats orally-administered 1% tween 20 dissolved in distilled water/Control (Group I); rats were orally-administered daidzein suspension (100mg/kg) for 7 days (Group II); rats intraperitoneally-injected with a single dose of ifosfamide (500 mg/kg) (Group III); rats orally-administered for 7 days with the daidzein (100mg/kg) before a single intraperitoneal dose of ifosfamide (500 mg/kg) at day 7 (Group IV). Twenty-four (24) hours after the end of treatment, determination of the malondialdehyde, reduced glutathione, and superoxide dismutase enzyme activity levels in the rats’ brain tissue homogenate were performed; in addition to the histopathological examination of the brain tissues sections. Results showed that the levels of malondialdehyde in brain tissue were significantly-increased (P<0.05) in (Group III/ifosfamide-only) rats compared to such level in the rats’ brain tissue of controls (Group I). Furthermore, the brain tissue level of the malondialdehyde was significantly-decreased (P<0.05) in rats of Group IV (orally-administered DZN prior to IFO) compared to such tissue level in rats of Group III. Moreover, the brain levels of each of the reduced glutathione and the superoxide dismutase enzyme activity were significantly-decreased (P<0.05) in (Group III) compared to each level in those of Group I. Additionally, the brain levels of each of the antioxidant parameters was significantly-increase (P<0.05) in Group IV rats compared to each of these tissue levels in rats of Group III.

As a results, daidzein has a protective effect against ifosfamide-induced neurotoxicity in rats via improving some selected oxidative stress parameters in male rats.

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Publication Date
Fri Mar 01 2013
Journal Name
Indian Journal Of Applied Research
Optical study of effect of thiourea on CdS thin films
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Abstract: This paper presents the results of the structural and optical analysis of CdS thin films prepared by Spray of Pyrolysis (SP) technique. The deposited CdS films were characterized using spectrophotometer and the effect of Sulfide on the structural properties of the films was investigated through the analysis of X-ray diffraction pattern (XRD). The growth of crystal became stronger and more oriented as seen in the X-ray diffraction pattern. The studying of X-ray diffraction showed that; all the films have the hexagonal structure with lattice constants a=b=4.1358 and c=6.7156A°, the crystallite size of the CdS thin films increases and strain (ε) as well as the dislocation density (δ) decreases. Also, the optical properties of the

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Publication Date
Wed Mar 01 2023
Journal Name
Journal Of Transportation Engineering
Effect of nanomaterials on the durability of hot mix asphalt
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Publication Date
Sun Apr 01 2007
Journal Name
Journal Of Engineering
Effect of Prestressing Force on Torsion Resistance of Concrete Beams
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Publication Date
Thu Feb 28 2019
Journal Name
Journal Of Engineering
Effect of Hydrated Lime on Moisture Susceptibility of Asphalt Mixtures
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Moisture induced damage can cause a progressive deterioration in the performance of asphalt pavement by the loss of adhesion between asphalt binder and aggregate surface and/or loss of cohesion within the binder in the presence of water. The objective of this paper is to improve the asphalt mixtures resistance to moisture by using hydrated lime as an anti-stripping additive. For this purpose, two types of asphalt binder were utilized; asphalt grades (40-50) and (60-70) with one type of aggregate of 19.0 mm aggregate nominal maximum size, and limestone dust as a mineral filler. Marshall method was adopted to find the optimum asphalt content. Essentially, two parameters were determined to evaluate the moisture susceptibili

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Publication Date
Wed Sep 27 2023
Journal Name
Journal Of Optics
Studying the responsivity and detectivity of GO/PSi/n-Si photo detector via drop casting technique
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Publication Date
Sun Jul 01 2018
Journal Name
Journal Of Global Pharma Technology
Synthesis, Characterization and Investigation Liquid Crystalline, Properties of 1, 2, 3-triazole Derivatives via Cycloaddition Reaction
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The new of compounds synthesized by sequence reactions starting from a reaction of 3-phenylenediamine or 4-phenylenediamine with chloroacetyl chloride to produce the compounds [I]a,b, then the compounds[I]a,b reacted with sodium azide to yield compounds[II]a,b that reacted 1,3-dipolarcycloaddition reaction with acrylic acid to give compounds [III]a,b these compounds reacted with methanol led to ester compounds[IV]a,b then reacted with hydrazine to give acid hydrazide [V]a,b . Finally compounds [V]a,b reacted with aromatic aldehydes to product shiff bases derivatives. The compounds characterized by mp. , IR, 1HNMR in addition to mass spectroscopy for some of them the liquid crystals properties were studied by using polarized optical microsco

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Publication Date
Wed Sep 27 2023
Journal Name
Journal Of Optics
Studying the responsivity and detectivity of GO/PSi/n-Si photo detector via drop casting technique
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Publication Date
Sun Mar 01 2009
Journal Name
Laser And Particle Beams
Surface morphology modifications of human teeth induced by a picosecond Nd:YAG laser operating at 532nm
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Publication Date
Sat Jan 01 2011
Journal Name
Iraqi Journal Of Physics
Calculation of Particle Emission Rates for Nucleon-Induced Reactions with non-Equidistance Spacing Model Dependence
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Nuclear emission rates for nucleon-induced reactions are theoretically calculated based on the one-component exciton model that uses state density with non-Equidistance Spacing Model (non-ESM). Fair comparison is made from different state density values that assumed various degrees of approximation formulae, beside the zeroth-order formula corresponding to the ESM. Calculations were made for 96Mo nucleus subjected to (N,N) reaction at Emax=50 MeV. The results showed that the non-ESM treatment for the state density will significantly improve the emission rates calculated for various exciton configurations. Three terms might suffice a proper calculation, but the results kept changing even for ten terms. However, five terms is found to give

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Publication Date
Tue Mar 31 2015
Journal Name
Al-khwarizmi Engineering Journal
Temperature Effect on Photovoltaic Modules Power Drop
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 Abstract

In order to determine what type of photovoltaic solar module could best be used in a thermoelectric photovoltaic power generation. Changing in powers due to higher temperatures (25oC, 35oC, and 45oC) have been done for three types of solar modules: monocrystalline , polycrystalline, and copper indium gallium (di) selenide (CIGS). The Prova 200 solar panel analyzer is used for the professional testing of three solar modules at different ambient temperatures; 25oC, 35oC, and 45oC and solar radiation range 100-1000 W/m2. Copper indium gallium (di) selenide module   has the lowest power drop (with the average percent

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