Asthma is a chronic respiratory disorder of airways characterized by inflammation, hyperresponsiveness, inflammatory cell infiltration, mucous secretion, and remodelling. Ammi majus is medicinal plant belong to family of Apiaceous which has anti-inflammatory and antioxidant activities. This study designed to investigate of anti-asthmatic activity of alcoholic extract of Ammi majus in improvement of asthma. Forty-eight healthy female mice divided to six groups Group I: the negative control group (distal water only), Group II: Positive control group (ovalbumin group), Group III: Ammi majus (64 mg/kg/day) with sensitization, Group IV:Ammi majus (128 mg/kg/day) with sensitization, Group V: Ammi majus (64 mg/kg/day) without sensitization, Group VI: Ammi majus (128mg/kg/day) without sensitization. Mice were sacrificed by diethyl ether and blood samples were collected to prepare of serum samples that used in ELISA kits for measuring of parameter IL-4, IL-5, IL-33, & IgE. Levels of all parameters (IL-4, IL-5, IL-33, & IgE) for mice of treated groups with alcoholic extract of Ammi majus were highly significant reduced (p<0.05) in compared to ovalbumin group.in conclusion, our results demonstrated that alcoholic extract of Ammi majus has a potent anti asthmatic activity that improved ovalbumin-induced asthma.
The current study was conductedas a pot experiment to determine the effect of soil texture on biological nitrogen fixation (BNF) of six most efficient local isolates, specified, of Bradyrhizobium. Cowpea (Vignaunguiculata L.), as a legume host crop, was used as a host crop and 15N dilution analysis was used for accurate determination of the amount of N biologically fixed under experimental parameters specified. Soils used are clay loam, sandy clay loam and sandy loam. Biological Nitrogen Fixation (BNF), in different soil textural classes, was as in the following order: medium texture soil > heavy texture soil > light textured soil. Statistical analysis showed that there is a significant variation in BNF % among six Iraqi isolates in the th
... Show MoreFumonisin B1 is a toxic compound produced by Fusarium verticillioides. Liver and kidney are the major organs considered target to FB1 toxicity that is characterized by apoptotic, necrosis, and regeneration. Thirteen local isolates of F. verticillioides isolated form maize samples that collected from local markets and silos in Baghdad. Morphological identification are occurred and confirmed by PCR and their ability to produce FB1 was detected using ELISA techniques, Thirty six male albino mice were divided into six groups. Each group orally gavaged with different concentration of FB1. After 24hours, all treated mice were examined to determine the concentration which killed half of animals and was considered as LD50, the remaining groups w
... Show MoreFifteenth of Cronobacter sakazakii were obtained from previous studies isolates were (infant formula, spinal fluid and bloods). The newborn mice and number was 15 obtaining healthy newborn mice from the Iraqi Center for Cancer and Medical Genetics whose ages ranged between 10-17 days and their weights 8.5 ± 1.25 gm, were divided into 3 groups. The samples were cut and placed in formalin, then placed in stabilizer and concentrations of alcohol (70%, 80%, 90%,100%) to complete dehydration after they were leached with xylene, embedded the samples paraffin wax (58°C) and sectioning the with thickness (5) micrometer and stained with Haematoxylin and Eosin stain. The results of an increase in the weight of the brain organ for the mi
... Show MoreSerine Palmitoyltransferase SPT is the key enzyme in the de novo sphingolipids biosynthesis pathway in eukaryotes, including the intracellular parasite Leishmania. Previous studies showed that this enzyme SPT is expressed only in divided promastigote forms and it is non-essential in the amastigotes form of Leishmania major, which is known as the old world leishmaniasis. In this study we have studied the viability of new world lesihamniasis, Leishmania mexicana. Cytotoxicity test used to determine the effect of the SPT inhibitor myriocin which did not significantly affect the viability of the two forms of the in vitro cultures of the parasite p<0.05, procyclic promastigotes and amastigotes, in which cell viability for miltefosine trea
... Show MoreThis work aimed to prepare and study the characteristic feature of lead nanoparticles (PbNPS) and follow its effects on some physiological aspects in rats.PbNPS was prepared by laser ablation of pure lead mass with a pulse of 500 and 100 mJ of energy. The results indicated that the wavelength was approximately 196 and the concentration was reported at 53,8967 mg / L. AFM, as the average diameter has been estimated at 69.93 nm. EFSEM shows the spherical shape of the particle.The experimental animals (rats) were divided into two groups, with seven rats for each one. The first group was a control and the second group was injected with 1 milliliter of PbNPS (53.8673 mg/l) per day for 45 days. Bioaccumulated lead ( in liver, spleen kidney and
... Show MoreDiabetes is a chronic disease which has reached pandemic proportions in a lot of countries of the world. In spite of the remarkable development in therapeutics chemistry, the usage of customary drugs is still a common practice for the treatment of diabetes. The current study was designed to investigate the effects of pomegranate seed oil (PSO) on kidney functions in the experimentally-induced diabetes in male rabbits. Diabetes was experimentally introduced by the intraperitoneal injection of alloxan monohydrate (150mg/kg BW). After three days of alloxan injection, samples were taken for the determination of glucose concentration. Serum glucose concentration of 200mg/ml was considered as an indication of animal diabetes. The experimental
... Show MoreSol-gel method was use to prepare Ag-SiO2 nanoparticles. Crystal structure of the nanocomposite was investigated by means of X-ray diffraction patterns while the color intensity was evaluated by spectrophotometry. The morphology analysis using atomic force microscopy showed that the average grain sizes were in range (68.96-75.81 nm) for all samples. The characterization of Ag-SiO2 nanoparticles were investigated by using Scanning Electron Microscopy (SEM). Ag-SiO2 NPs are highly stable and have significant effect on both Gram positive and negative bacteria. Antibacterial properties of the nanocomposite were tested with the use of Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) bacteria. The results have shown antibacteri
... Show MoreThe study was aims to evaluate the antimicrobial acttvtty of petroleum ether extracts from leaves , seeds and root of Zygophyllum fabago , against several microorganisms including gram negative bacteria (Pseudomonas aeruginosa & Escherichia coli), gram positive bacteria (Staphylluwccus aureus & Bacillus subtilis), in addition to yeast (Candida albicans).
While the results of sensitivity of the microorganisms to words petroleum ether extracts showed different activity , petrolewn ether extract of seeds showed more antimicrobial
... Show MoreRifampicin (RF) considered a hepatotoxic drug. Is one of the first line successful drugs of management of tuberculosis. To reduce injury and protect liver from adverse effect of Rifampicin, this study was designed to investigate the activity of Nigella Sativa (NS) seeds powder aqueous suspension to hepato protection against Rifampicin.
For conducting this study,24 male albino rats were divided into four groups and all treated orally as follow; group І (control), received normal saline alone; group II, received RF (50mg/kg body weight/day); group III received NS it's called normal dose, (2g/kg body weight day); group IV RF (50mg/kg body weight) + NS (2g/kg body weight).Respectively for 28 days. Blood samples obtained for estimation of
Reservoir simulation models are utilized by oil and gas companies with a purpose to develop fields. Expansions and improvements in simulation software have lessened the time to develop a model. Simulating the reservoir aims to realize fluid flow, physical, and chemical procedures happening in a hydrocarbon reservoir adequately well for the reason of improving hydrocarbon recovery under various working stipulations. Grid-orientation effects are complicated problem in numerical reservoir simulation. These influences were coming when utilized of numerical utilization mechanism to conditions characterizing physically inconstant displacement procedure. These impacts happen in an assortment