Preferred Language
Articles
/
bijps-1794
An update on Nanoparticle Formulation Design of Piperine to Improve its Oral bioavailability: A Review
...Show More Authors

Piperine, a crystalline alkaloid compound isolated from Piper nigrum, piper longum, and other types of piper, has had many fabulous pharmacological advantages for preventing and treating some specific diseases, such as analgesic, anti-inflammatory, hepatoprotective, antimetastatic, antithyroid, immunomodulatory, antitumor, rheumatoid arthritis, osteoarthritis, Alzheimer's, and improving the bioavailability of other drugs. However, its potential for clinical use through oral usage is hindered by water solubility and poor bioavailability. The low level of oral bioavailability is caused by low solubility in water and is photosensitive, susceptible to isomerization by UV light, which causes piperine concentration to decrease. Many different formulation approaches have been applied to improve the poor oral bioavailability of piperine. There have been oral formulation strategies that have been successfully implemented in increasing the solubility and bioavailability of piperine within the body, such as the formulation of nanoparticles, nanosuspensions, salt formation, liposomes, complexation using polymers, micro/nano-emulsions, and solid dispersions. This review presents a summary of piperine biopharmaceuticals, new formulation design approaches to improve oral bioavailability of piperine, and several techniques and methods for conducting selective and sensitive analysis of piperine in biological fluids.

Scopus Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Sat Jun 15 2024
Journal Name
Journal Of Baghdad College Of Dentistry
Validity of digital interceptive orthodontic/therapeutic protocols post global pandemics: A review
...Show More Authors

Background: Aggressive global pandemics such as COVID-19 can disrupt societies tragically, imposing a suspension to almost every field throughout the world; the orthodontic treatment and follow-up is no exemption. Objectives: To provide practical recommendations about resuming treatment for orthodontic patients during the “Return-to-Practice” phase and emphasize the validity of certain digital interceptive measures post global pandemics to minify the risk of infection spread. Materials and Methods: Sources of information pertaining to orthodontic/therapeutic implications during the COVID-19 pandemic were searched using electronic databases including COVID-19 Open Research Dataset (CORD-19 2020), Google Scholar, Scopus, PubMed, M

... Show More
View Publication Preview PDF
Scopus (1)
Crossref (1)
Scopus Crossref
Publication Date
Thu Aug 21 2025
Journal Name
Journal Of Health And Biology
Distribution and Species Diversity of the Dove Genus Streptopelia: A Systematic Review
...Show More Authors

Some species, such as the Eurasian Collared-Dove (S. decaocto) are fast expanding around the planet, while others, such as the European Turtle-Dove (S. turtur), are experiencing precipitous population declines. Climate change, habitat loss, greater cultivated areas, and hunting pressure are the major threats to the diversity of Streptopelia. A few species require urgent conservation action. Priority for subsequent research should be to redress outstanding taxonomic uncertainties, ascertain the effect of climate change on distributions, and put in place conservation measures for declining taxa. We provide here a detailed review on how it is possible to understand the diversity of Streptopelia and how such an understanding can con

... Show More
View Publication
Crossref
Publication Date
Fri Jun 20 2025
Journal Name
Journal Of Kufa For Chemical Sciences
Studying Analytical Methods for Monitoring of Antibiotics in Environmental Waters, A review
...Show More Authors

In recent years, there has been a rise in interest in the study of antibiotic occurrence in the aquatic environment due to the negative consequences of prolonged exposure and the potential for bacterial antibiotic resistance. Most antibiotic residues from treated wastewater end up in the aquatic environment as they are not eliminated in facilities that treat wastewater. Antibiotics must be identified in influent and effluent wastewater using reliable analytical techniques for several reasons. Firstly, monitoring antibiotic presence in aquatic environments. Secondly, assessing environmental risks, computing wastewater treatment plant removal efficiencies, and estimating antibiotic consumption. Therefore, this work aims to provide an overview

... Show More
Preview PDF
Publication Date
Mon Feb 01 2021
Journal Name
Journal Of Engineering
The Synergic Effects of Mineral Admixtures in Ternary Blended Cement: A Review
...Show More Authors

In the last decades, using mineral admixture in concrete became very necessary to improve concrete properties and reduce CO2 emissions associated with the cement production process. Subsequently, more sustainable concrete can be obtained.  Ternary blended cement containing two different types of mineral admixture can achieve ambitious steps in this trend. In this research, the synergic effects of mineral admixtures in ternary blended cement and its effects on concrete fresh properties, strength, durability, and efficiency factors of mineral admixture in ternary blended cement, were reviewed. The main conclusion reached after reviewing many literature pieces is that the concrete with ternary blended cement

... Show More
View Publication Preview PDF
Crossref
Publication Date
Sat Jun 30 2012
Journal Name
Al-kindy College Medical Journal
Angiolymphoid Hyperplasia with Eosinophilia : a Case Report and Review of the Literature
...Show More Authors

A case of angiolymphoid hyperplasia with eosinophilia (ALH) is reported in a 42-year-old woman who developed multiple nodules behind the ear. Angiolymphoid hyperplasia with eosinophilia usually occurs on the head and neck of young adults and is more common in women than in men. Characteristic histologic features of ALH present in this case included proliferation of thick-walled blood vessels lined by prominent endothelial cells, infiltration of the interstitium by chronic inflammatory cells (mainly eosinophils), and presence of lymphoid follicles with germinal centers. The patient referred for surgeon for complete excision. in this context , cases previously described in the literature, and the differential diagnosis of ALH are discussed

... Show More
View Publication Preview PDF
Publication Date
Sat Feb 01 2025
Journal Name
Journal Of Chemical Reviews
Importance of Coordination Chemistry in Anticancer, Antimicrobial, and Antioxidant Therapy: A Review
...Show More Authors

Metals are vital cellular components chosen by nature to perform various critical metabolic activities in living beings. Metal complexes are keys in catalysis, material production, photochemistry, and biological systems. Many studies were conducted to determine their role in biological processes. Transition metal complexes are becoming more important as therapeutic compounds due to their role in inorganic chemistry. Recent advances in inorganic chemistry have created transition metal complexes with target organic ligands that may be therapeutic. Researchers interested in medical applications may find this study useful since it highlights the importance of metals and current developments in medicinal chemistry, such as new approaches to crea

... Show More
Publication Date
Tue Jun 14 2016
Journal Name
Applied Organometallic Chemistry
Synthesis and antioxidant activities of Schiff bases and their complexes: a review
...Show More Authors

Schiff bases, named after Hugo Schiff, are aldehyde- or ketone-like compounds in which the carbonyl group is replaced by imine or azomethine group. They are widely used for industrial purposes and also have a broad range of applications as antioxidants. An overview of antioxidant applications of Schiff bases and their complexes is discussed in this review. A brief history of the synthesis and reactivity of Schiff bases and their complexes is presented. Factors of antioxidants are illustrated and discussed. Copyright © 2016 John Wiley & Sons, Ltd.

View Publication Preview PDF
Scopus (234)
Crossref (225)
Scopus Clarivate Crossref
Publication Date
Mon Apr 01 2024
Journal Name
Al-kindy College Medical Journal
Radiological Modalities for the Assessment of Fetal Growth Restriction: A Comprehensive Review
...Show More Authors

Fetal growth restriction is a significant contributor to fetal morbidity and mortality. In addition, there are heightened maternal risks associated with surgical operations and their accompanying dangers. Monitoring fetal development is a crucial objective of prenatal care and effective methods for early diagnosis of Fetal growth restriction, allowing prompt management and timely intervention to improve the outcomes. Screening for Fetal growth restriction can be achieved via many modalities; it can be medical, biochemical, or radiological. Some recommended combining more than one for better outcomes. Currently, there is inconsistency about the best method of Fetal growth restriction screening.   In this review, a comprehensive

... Show More
Scopus (23)
Crossref (19)
Scopus Crossref
Publication Date
Wed Jan 14 2026
Journal Name
Cancers
Advances in the Pathophysiology and Management of Cancer Pain: A Scoping Review
...Show More Authors

Background/Objectives: Cancer pain affects 55–95% of patients with advanced malignancy, representing a complex syndrome involving nociceptive, neuropathic and nociplastic mechanisms. Despite therapeutic advances, two-thirds of patients with metastatic cancer experience inadequate pain control. This scoping review synthesizes recent advances in cancer pain pathophysiology and management, focusing on molecular and cellular mechanisms, emerging pharmacological, interventional and technological therapies and key evidence gaps to inform future precision-based pain management strategies. Methods: Following PRISMA-ScR methodology, we searched PubMed, Embase, Scopus, and Web of Science for studies published between January 2022 and Septem

... Show More
View Publication
Scopus (7)
Crossref (9)
Scopus Crossref
Publication Date
Wed Jul 15 2026
Journal Name
European Journal Of Dentistry
Airway-centric Orthodontics: A Narrative Review of Current Evidence and Clinical Implications
...Show More Authors
Abstract<p>Airway-centric orthodontics has been proposed as a conceptual framework that extends the traditional understanding of craniofacial development, functional disturbances, and orthodontic treatment outcomes beyond a purely dental perspective. This approach focuses on the potential interplay among upper airway characteristics, breathing patterns, and orofacial muscle function in influencing facial growth and occlusal relationships. This narrative review aims to outline the theoretical foundations of airway-centric orthodontics and to synthesize current evidence regarding the associations among upper airway characteristics, craniofacial morphology, and orthodontic interventions. A compr</p> ... Show More
View Publication Preview PDF
Scopus Crossref