Preferred Language
Articles
/
bijps-1741
Lipid -Lowering Effect of Polysaccharide (Pectin) of Viscum album L. Plant in Rats
...Show More Authors

Disturbances of lipid metabolism is a predisposing factor of cardiovascular diseases, which are accompanied by high mortality rates of the population - ischemic heart disease and ischemic stroke. Plant polysaccharides can be promising remedies for correction of lipid imbalance.

In this regard, the aim of the study was to assess the hypolipidemic activity of polysaccharides isolated from the leaves of mistletoe.

The test-object was the leaves of the white mistletoe (Viscum album L.) growing on the apple (Malus domestica Borkh.), and the pear (Pyrus communis L.). Polysaccharides (water-soluble polysaccharides and pectin substances) were quantitatively determined by the gravimetric method followed by reprecipitation from ethanol. The qualitative composition was evaluated by thin layer chromatography. Functional groups in polysaccharides were determined by titrimetric method. The hypolipidemic activity of the obtained polysaccharides was determined under oral administration at a dose of 100 mg / kg in Wistar rats by the change of the concentration of total cholesterol, triglycerides, LDL and HDL cholesterol. The change of the content of cholesteryl ester transfer protein and Niemann-Pick C1-Like1 protein was also determined.

As a result, it was found that among the polysaccharides in the leaves of mistletoe, pectin substances are predominate, which belong to the group of low-esterified pectins. A significant content of free carboxyl groups in pectins from the leaves of mistletoe was also found. The study of hypolipidemic activity showed that, among the polysaccharides of mistletoe leaves, pectin substances exert a more pronounced effect on lipid metabolism, the use of which reduced the content of triglycerides, total cholesterol and LDL cholesterol with an increase in LDL cholesterol in rats, probably due to a decrease in the activity of cholesteryl ester transfer protein and Niemann-Pick C1-Like1 protein. At the same time, at the level of the trend, mistletoe pectins showed a higher level of activity than analogous compounds obtained from the leaves of host-plants. It should be noted that the severity of the pharmacological effect of mistletoe pectins did not depend on the host-plants.

Thus, based on the obtained results, it can be assumed that pectins obtained from the mistletoe leaves can be a potentially effective and safety hypolipidemic agent.

Scopus Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Fri May 01 2020
Journal Name
European Journal Of General Dentistry
Effect of plant-extract disinfectant solutions on the specific properties of reinforced maxillofacial silicone elastomers with nanofiller and intrinsic pigment
...Show More Authors
Abstract<p> Objective This study aimed to evaluate the effects of disinfectant solutions, namely, the alcoholic extract of Salvadora persica L. (A1 = 10% and A2 = 15%) and chlorhexidine digluconate (A3 = 2%), on the tear strength and hardness of room temperature vulcanizing (RTV) VST50F and heat temperature vulcanizing (HTV) Cosmesil M511 silicone elastomers before and after reinforcement with nanofillers (TiO2) and intrinsic pigment. Materials and Methods: A total of 320 specimens were prepared, with 160 specimens each for RTV and HTV silicone. Forty specimens were evaluated before disinfection and divided into two equal groups, namely, control (without additive) and experimental (with ad</p> ... Show More
View Publication
Scopus (4)
Crossref (7)
Scopus Crossref
Publication Date
Thu Dec 29 2016
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Effect of Water Extracts of SomeMedicinal Plants OnGermination Percentage and Development of Plumule and Radicle Growth Anethum graveolens L.
...Show More Authors

 An experiment was conducted at the laboratories of College of Agriculture – Kerbala University during 2016. The aim of this study was to the effect of water extracts of medicinal plants germination percentage and development of plumule and radicle growth .The completely randomized design with three replicates was usedin each experiment consisted of water extracts (T1= Distilled water),(T2= Eruca sativa Eruca sativa L),(T3= Fenugreek ﺍﻟﺤﻠﺒﺔTrigonella foenum - graecum L),(T4= Sweet FennelFoeniculum vulgare.Mill),(T5=Borage Anchusa strigosa Lab),(T6=Dill Anethum graveolens L) ,(T7=Black cuminNigella Sativa L),(T8=Cumin Cuminumcyminum L),(T9=  CorianderCoriandrum sativum L. ). Results of Lab.

... Show More
View Publication Preview PDF
Publication Date
Sun Mar 07 2010
Journal Name
Baghdad Science Journal
The Effect of Aqueous and Alcoholic Extracts of Punica granatum L. Pericarp on Hemolysin Production of several Bacterial species
...Show More Authors

Four local hemolysin producer bacterial isolates were selected, tow of them gram negative bacteria (Escherichia coli ,Pseudomonas aeruginosa ) and the other two were gram positive bacteria (Staphylococcus aureus , Bacillus cereus ). Minimum inhibitory concentration of the aqueous and alcoholic extracts of Punica granatum L. pericarp were determined towards the four bacterial isolates ,results obtaind showed that MICs of the aqueous extract were 200 mg/ml for E .coli and P. aeruginosa isolates while were 5 mg/ml and 2 mg/ml for B. cereus, S. aureus , respectively The MICs for the ethanolic extract were 50 mg/ml , 20 mg/ml ,1 mg/ml ,0.5 mg/ml for E. coli ,P. aeruginosa ,B. cereus ,S. aureus , respectively. The effect of Sub-MICs o

... Show More
View Publication Preview PDF
Crossref
Publication Date
Tue Jan 01 2013
Journal Name
Scientific Journal Of King Faisal University
Effect of supplementing male guinea fowls diet with different levels of L - carnitine on the characteristics of their semen
...Show More Authors

Carnitine is a regulatory amino acid, necessary for the metabolism of long-chain fatty acids in the ß - oxidation, and it is important in the organization of the work of the blood brain barrier, and is very important in the treatment of infertility and sexual apathy. This study was conducted at the Poultry Farm of the Department of Animal Resource, College of Agriculture, University of Baghdad during the period from 15/2/2011 to 1/8/2011. The aim of this study was to investigate the effect of dietary supplementation with different levels of L - carnitin e on semen characteristics of guinea fowl male. A total of 24 guinea fowl male, 30 weeks of old were used in this study. Birds were randomly distributed into 4 groups (C0, C100, C200, C300)

... Show More
Scopus (3)
Scopus
Publication Date
Thu May 15 2025
Journal Name
Journal Of Animal Health And Production
Functional and Histological Study of Liver in Adult Rats Treated with Different Doses of Melatonin
...Show More Authors

his study aimed to evaluate the effects of different doses of melatonin on liver function in adult rats. Eighteen Wistar adult albino rats (Rattus norvegicus), approximately 13–16 weeks old and weighing 230 ± 10 g, were randomly divided into three groups (n=6 per group) and treated orally for 30 days as follows: Group A1 received 10 mg/kg body weight (B.W) of melatonin; Group A2 received 20 mg/kg B.W of melatonin; and the control group (Group A) received distilled water. At the end of the treatment period, blood samples were collected via cardiac puncture, and serum was separated for biochemical analysis. Parameters assessed included oxidative stress markers (malondialdehyde (MDA), reduced glutathione (GSH)) and liver enzymes (aspa

... Show More
View Publication Preview PDF
Crossref
Publication Date
Tue Oct 29 2024
Journal Name
Journal Of Advanced Pharmacy Education And Research
Evaluating the effects of different doses of fimasartan on methotrexate-induced renal inflammation in rats
...Show More Authors

The nephrotoxicity induced by methotrexate is a severe condition that greatly affects its therapeutic potential and has a significant inflammatory component. Fimasartan is an angiotensin receptor blocker that offers organ-protective effects and may be useful in mitigating renal injury. The present study explored the anti-inflammatory potential of two doses of fimasartan against methotrexate-mediated nephrotoxicity. Albino rats were intraperitoneally administered a single methotrexate (20 mg/kg). Intraperitoneal treatment with fimasartan (5 or 10 mg/kg/day) was initiated on day two after methotrexate injection and continued for seven consecutive days. Methotrexate significantly increased serum urea, creatinine, and NGAL concentrations. It al

... Show More
View Publication Preview PDF
Scopus Crossref
Publication Date
Thu Oct 17 2024
Journal Name
Veterinary World
Characterization of food color additives and evaluation of their acute toxicity in Wistar albino rats
...Show More Authors

Background and Aim: The use of food dyes can cause certain diseases, such as anemia and indigestion, along with other disorders, tumors, and even cancer. Therefore, this study aimed to determine the chemical nature and toxicity of some commercial dyes locally used in processed foods compared with standard food dyes. Materials and Methods: Three types of standard and commercial food color additives (Sunset Yellow, Tartrazine, and Carmoisine) were extensively examined. The chemical structures and functional groups of the dyes were evaluated by Fourier-transform infrared (FTIR) spectroscopy. The melting temperatures of the dyes were also determined by chemical thermal analysis. The acute toxicity test to evaluate the standard and commercial

... Show More
View Publication Preview PDF
Scopus Clarivate Crossref
Publication Date
Tue Jan 01 2019
Journal Name
Veterinary World
Bacterial isolation from internal organs of rats (Rattus rattus) captured in Baghdad city of Iraq
...Show More Authors

Aim: Rats are accused in disseminating many zoonotic diseases. This study aimed to isolate and identify bacteria from internal organs of rats captured in Baghdad City, Iraq. Materials and Methods: A total of 120 black rats (R. rattus) were trapped from different areas in Baghdad city. Rats were kept in individual plastic cages for 3 h before euthanizing. Deep pharyngeal swab, intestinal content, urine, and pieces of the liver and spleen, lung, kidney, and brain were obtained aseptically. The specimens were inoculated into peptone water and incubated at 37°C for 24 h for enrichment. A loopful of each specimen was then subcultured onto MacConkey Agar, Blood Agar, and Mannitol Salt Agar. CHROMagar O157 H7 and CHROMagar Listeria were u

... Show More
View Publication Preview PDF
Publication Date
Tue Jun 28 2011
Journal Name
Iraqi Journal Of Pharmacy
Effects of different concentrations of aqueous green tea extract against methotrexate-induced nephrotoxicity in rats
...Show More Authors

View Publication
Crossref
Publication Date
Sun Jan 01 2023
Journal Name
Pakistan Journal Of Botany
Efficiency of plant extracts on Aspergillus growth and aflatoxin B1 production in Zea mays
...Show More Authors

The detection of fungi contaminating maize grain and the effect of four plant extracts Azadirachta indica, Eucalyptus globulus Glycyrrhiza glabra and Zingiber officinale on the growth of A. flavus and its ability to produce AflatoxinB1. The results showed that the incidence of Aspergillus spp., was 52.75% of the isolated fungi, of which 29.50% was due to Aspergillus flavus, followed by Penicillium spp., with an incidence of 21.06%, and then Fusarium spp., with a rate of 18.13%. The percentage of toxin-producing A. flavus isolates reached 70.8% out of 24 isolates. The results showed the effect of alcoholic plant extracts at a concentration of 10 mg/ml on the fungal growth activity of A. flavus, the alcoholic extract of neem leaves was superi

... Show More
View Publication Preview PDF
Scopus (9)
Crossref (2)
Scopus Crossref