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Ameliorative Role of Nutraceutical Quercetin and its Derivatives Against Cognitive Impairment Process Induced by Lead Exposure in Drosophila melanogaster(Fruit Fly)

Cumulative lifetime lead (Pb) exposure has been associated with accelerated declines in cognition through the free radical generation and epigenetic effects. Several pieces of literature have identified a correlation between exposure to lead and neurodegenerative disorders. Harwich strain Drosophila melanogaster was exposed to lead acetate for two weeks, and changes in pulse transmission by acetylcholinesterase and systemic redox were evaluated. Besides, molecular docking studies of acetylcholinesterase against Quercetin and its most common derivatives contained in food have been performed. Pharmacokinetic studies on Quercetin and its derivatives have also been performed in silico toxicity. The data obtained showed alterations in antioxidant enzymes and molecules such as catalase, glutathione-S-transferase, and glutathione. Upregulation of acetylcholinesterase activity was observed after treatment with Quercetin. In molecular docking tests, Quercetin and its derivatives were found to bind to acetylcholinesterase's active and peripheral pockets. Pharmacokinetic studies demonstrate moderate solubility, high therapeutic index, excellent absorption potential, hepatoprotective and non-mutagenic properties. With other antioxidant molecules, Quercetin may also play a crucial role in avoiding the development of Alzheimer's and associated antioxidant disorders.

 

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Publication Date
Fri Nov 24 2023
Journal Name
Iraqi Journal Of Science
Influence of MHD for Newtonian Fluid and Heat Transfer in Microchannals between Two Parallel Plates Using HAM

The aim of this paper is the study of the influence magnetic field on steady state
flows and heat transfer in microchannels between two parallel plates.
It is found that the motion equations are controlled by many dimensionless
parameter, namely magnetic field parameter M Reynolds number Re, physical
quantity at wall W and Knudsen number Kn also found that the energy equations
are controlled by many dimensionless parameter, namely magnetic field parameter
M Reynolds number Re, physical quantity at wall W and Knudsen number Kn ,
Prinkman number Br and Peclet number Pe.
The equations which controlled this type of fluid flow are complicated, so finding
an analytical solution is not easy.
We obtained the velocit

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Publication Date
Tue Jul 01 2008
Journal Name
Bulletin Of The Iraq Natural History Museum (p-issn: 1017-8678 , E-issn: 2311-9799)
THE STUDY OF MINERALOGICAL AND MICROFACIES ANALYSIS SHIRANISH FORMATION WELL (KH-6) ANSAB AREA IN SOUTHERN IRAQ

The study of Shiranish Formation rocks in southern part of Iraq at Ansab area well (KH-6)
were carried out. The formation is tongued with tayarat formation, which bounded from top
and bottom, the upper tongue at thickness 49m. and tongued at depth (476-525m.) the lower
tongue at thickness 4m. tongued at (541-537m.).
The rocks of this formation were divided into three sedimentary microfacies:
1- Dolomitized formininferal Wackestone facies.
2- Dolomitized formininferal Mudstone facies.
3- Dolostone facies.
34 slides were investigated depending on mineralogical, compositional and biological
processes and compared diagenesis which reflect open marine shelf at lower part of formation
(F.Z.2) (S.M.F.8), but at the

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Publication Date
Sat Aug 01 2015
Journal Name
Euphrates Journal Of Agricultural Science
MEASURES OF SPECIFIC PRODUCTIVITY, ACTUAL TIME, APPEARANCE AND TILLAGE DEVIATION FOR TWO PLOWS MOSTLY USED IN IRAQ

Experiment was conducted in Baghdad, three factor were used in this research included Two types of Plows included moldboard and disk plows which represented the main plot, Three forward speeds of the tillage was the second factor included 1.85, 3.75 and 5.62 km / h which represented sup plot , and Three levels of Soil Moisture was third factor included 21, 18 and 14 % in all of Vertical and Lateral Plowing Deviation, Practical and specific productivity, actual time for plowing one donam and appearance (goodness) of Tillage represented by the number of clods > 10 cm in silt clay loam soil with depth 22 cm were studied. the experiment was used Split – split plot design under randomized complete block design with three replications and Le

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Publication Date
Sat Feb 02 2019
Journal Name
Journal Of The College Of Education For Women
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Publication Date
Mon May 22 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Direct and Inverse Inequalities for Jackson Polynomials of 2-Periodic Bounded Measurable Functions in Locally Clobal Norms

Convergence prop erties of Jackson polynomials have been considered by Zugmund
[1,ch.X] in (1959) and J.Szbados [2], (p =ï‚¥) while in (1983) V.A.Popov and J.Szabados [3]
(1 ï‚£p ï‚£ ï‚¥) have proved a direct inequality for Jackson polynomials in L
p-sp ace of 2-periodic bounded Riemann integrable functions (f R) in terms of some modulus of
continuity .
In 1991 S.K.Jassim proved direct and inverse inequality for Jackson polynomials in
locally global norms (L
,p) of 2-p eriodic bounded measurable functions (f L) in terms of
suitable Peetre K-functional [4].
Now the aim of our paper is to proved direct and inverse inequalities for Jackson
polynomials

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Publication Date
Sun Jul 02 2023
Journal Name
Iraqi Journal Of Science
RT PCR Detection and Propagation of Respiratory Syncytial Virus in Human Lung Carcinoma Cells (A549) cell line

In this study negative result of real-time reverse transcription-QPCR (RT-PCR) assay
tests of Influenza virus of nasal screetion and throat swap samples of Iraqi patients
hospitalized with signs and symptoms of an upper respiratory tract infection in Central
Republic Health Laboratory in Iraq were tested for Respiratory Syncytial Virus
infection by RT PCR .Positive samples was 4 out 0f 20 were used .Viral isolation was
done on a monolayer of 70-80% confluent Human Lung Carcinoma Cells (A549) cell
line and incubated at 33ºC for 4 days .Syncytia was observed in 3 positive samples.

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Publication Date
Sun Jan 30 2022
Journal Name
Iraqi Journal Of Science
The Effects of Zinc and Vitamin C Supplementation on the Glycemic Profile in Type 2 Diabetic Patients

     Diabetes mellitus (DM) is the most common endocrine disorder and one of the highly progressive diseases which is indicated by high blood sugar (hyperglycemia). The present study aims to study the effects of treatment with zinc and vitamin C on glycemic profile [fasting blood sugar (FBS), glycated haemoglobin (HbA1C), and insulin hormone level] in type 2 diabetic patients. The study included 56 diabetic patients [30 without foot ulcers (15 without zinc and vitamin C supplements, 15 with zinc and vitamin C supplements) and 26 with foot ulcers (15 without zinc and vitamin C supplements, 11 with zinc and vitamin C supplements)]. Also, 15 healthy persons were used as a control group. The patients were enrol

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Publication Date
Mon Jan 01 2018
Journal Name
Al–bahith Al–a'alami
The Interactive Relationship between the Formation Elements and their Implications in the Structure of the Television Image

The image of television dominates the cognitive and artistic motivations. It is the formulation of ideas and visions along with its documentary ability. It is the main element in television work as it is a story that is narrated in pictures. Therefore, attention to image building is a major point of gravity in the work structure as a whole. On the image is the element carrying all aesthetic and expressive values of news and information directly to the hints that work to stimulate and stir the imagination of the recipient to evoke mental images added to the visual images to deepen the meanings.
All visual arts carry elements and components that follow in a particular pattern to give special meanings and specific connotations. However,

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Publication Date
Thu Mar 30 2023
Journal Name
Iraqi Journal Of Science
Facies Architecture and Diagenetic Features Development of Albian-Early Turonian Succession in Luhais Oil field, Southern Iraq

Clastic-carbonate succession which including the Nahr Umr and Mauddud Formations are represented a part of Albian-Early Turonian Sequence (Wasi`a Group). The present study includes Petrography, microfacies analysis, depositional environment, digenetic development, and reservoir characterization for seven boreholes (Lu-2, Lu-4, Lu-5, Lu-8, Lu-13, Lu-14 and Lu-39) within Luhais Oil field South Iraq.
There are six type of carbonate microfacies were recognized in the Mauddud Formation:- Orbitolina - Milliolids wackestone to packstone Orbitolina wackestone to packstone, miliolids wackestone, Peloidal wackestone to packstone, Ooides to Peloids grainstone and bioclastic Wackestone - Packstone. These microfacies are represented three depositi

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Publication Date
Thu Jun 23 2022
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Flow Injection Spectrophotometric Technique for Determining of Genistein in Pure and Supplements Formulations Through Diazotization Coupling Reaction

Genistein (GEN) is The major isoflavone found in soybeans, has a number of cardiovascular health benefits, Postmenopausal syndrome and osteoporosis. A direct flow injection analysis method for estimation of (GEN) in pure and supplements formulation . This system is based on diazotization coupling reactions between procaine penciline (PR) and genistein in basic medium, they formed yellow dyes have maximum absorption at 416 nm. Calibration curve were constructed over different GEN concentrations, linearity for GEN was 10-100 µg.mL-1 and detection limits of 1.51 ?g/mL. In the FIA technique, all analytical factors were analyzed and optimized. The established method was successfully used to determine GEN in the formulations of its supplement

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