Preferred Language
Articles
/
bijps-1188
Synthesis of Mutual Prodrugs of Secnidazole and Ciprofloxacin and study Their Physicochemical Properties
...Show More Authors

  Secnidazole was linked with ciprofloxacin as mutual prodrugs to get antibiotics with broader spectrum of activity, improved physicochemical properties and given by single dose to improve patient’s compliance. Furthermore, they provide structural modifications to overcome bacterial adaptation. The structures of the synthesized compounds were confirmed using FT-IR, mass spectrometry, elemental microanalysis (CHNO) and some physiochemical properties. This modification was led to an increase in Log P values for Mutual I (Log P 1.114) and Mutual II (Log P 1.97) compared with its values for Secnidazole (Log P -0.373) and ciprofloxacin (Log P -0.832). The solubility of prodrugs had been determined in different media, Mutual II showed 144-fold increase in aqueous solubility compared to ciprofloxacin. Taste evaluation by panel method showed palatable taste in prodrugs compared to the parent drugs. The synthesized compounds were screened for their antimicrobial activity against different bacterial strains which are, Staphylococcus aureus, Pseudomonas aeruginosa, E. coli and Klebsiella pneumonia. The prodrugs have revealed excellent antibacterial activities compared with the parent compounds. Chemical hydrolysis study at pH (1.2 and 7.4) has indicated that these compounds may pass unhydrolyzed through the stomach and produce enough stability to be absorbed from the intestine as indicated by t1/2 values.

Scopus Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Wed Jun 01 2022
Journal Name
Journal Of The College Of Languages
The Multifunctional Morphemes in Kurdish Language the Morpheme Le as an example
...Show More Authors

Kurdish language multifunctional morphemes indicate the different functional morphological, syntactical, and semantic tasks of the morphemes. The present study discusses the multifunctional task of the Morpheme Le in Kurdish Language. The Morpheme Le has marginally been included in other studies, yet up to the present times, there has not been a research inclusively dedicated to thoroughly discuss and clarify its multifunctional aspects. The present study is divided into two chapters: Chapter one discusses the theoretical aspect of chapter two that is entirely concerned with the practical aspect of the morpheme Le. The first part of chapter one sheds light on the morphological aspect of the morpheme while part two discusses

... Show More
Preview PDF
Crossref
Publication Date
Wed Sep 29 2021
Journal Name
College Of Islamic Sciences
The Juristic Rulings Concerning Those in Debts
...Show More Authors

Abstract:

This research aimed to shed light on the juristic rulings concerning those in debts. It adopted the inductive approach, the analytical approach and the comparative approach. It tackled the following issues: definition of Zakat, the channels of paying Zakat, definition of those in debts, types of those in debts, those in debts who are not entitled to take Zakat, their cases, spending money by those in debts if taken by those in debts and the poor, and when those in debts become rich before paying their debts, and the ruling on paying the debt of the dead indebted from the Zakat money.

The most important results of the research are as follows:

Muslim jurists

... Show More
View Publication Preview PDF
Publication Date
Sun Jul 09 2023
Journal Name
Journal Of Engineering
The sustainable urban development in Al_Kharkh historic center
...Show More Authors

The problems of urban historic centers are considered some of the subjects which are widely dealt with in urban studies since the middle of the 20th century. literature of urban development have raised it , beside the fact that large number of urban development projects of the historical centers in many cities of the world ,and emerged from the application of these new problems projects added their original urban problems , because these projects have dealt with the physical structures with the neglect of the social and economic sides, which are the base in sustainable development nResearch problem was elaborated as : The unclearly of knowledge of the potentials of the sustainable development in solving the urban problems of historic cen

... Show More
View Publication Preview PDF
Crossref (2)
Crossref
Publication Date
Sun Sep 25 2022
Journal Name
Modern Sport
استعمال تمرينات خاصة وفق جهاز verti max وتأثيرها في تطوير تحمل الخاص للذراع الرامية وانجاز رمي الرمح للاعبيين دون ال 16 سنة
...Show More Authors

تكمن أهمية البحث من الاستفادة من تمرينات الخاصة بمساعدة استعمال أي جهاز تدريبي مثل استعمال جهاز (Vertimax) فإِنَّ هذهِ التدريبات تساعد في تطوير التحمل الخاص وفقًا لما يتطور من قدرات بدنية باستعمال هذا الجهاز، ومن هنا برزت مشكلة البحث انه من المهم  للاعب ان يعمل على الروافع الجسم للحصول على اداء افضل في عملية الرمي والحصول على افضل انجاز لهذة الفعالية باستعمال جهاز تدريبي جديد حيث يسلط مقاومات متعددة في ان وا

... Show More
View Publication
Crossref
Publication Date
Tue Oct 20 2020
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Solving Nonlinear Second Order Delay Eigenvalue Problems by Least Square Method
...Show More Authors

     The aim of this paper is to study the nonlinear delay second order eigenvalue problems which consists of delay ordinary differential equations, in fact one of the expansion methods that is called the least square method which will be developed to solve this kind of problems.

View Publication Preview PDF
Crossref
Publication Date
Wed Mar 30 2022
Journal Name
College Of Islamic Sciences
أجـــــوبة الحافظ محمد البرزالي على سؤالات العز ابن الحاجب في الجرح والتعديل
...Show More Authors

ملخص البحث بالعربي

عنوان البحث : أجـــــوبة الحافظ محمد البرزالي على سؤالات العز ابن الحاجب في الجرح والتعديل

يهدف البحث : إلى جمع أجوبة الحافظ أبي عبدالله محمد البرزالي في الجرح والتعديل، ودراستها.

يتكون البحث من : مقدمة، وتمهيد، نص السؤالات، وخاتمة، وفهارس.

المقدمة : تسمية الموضوع، وسبب اختياره، وأهميته .

والتميهد : ترجمة مختصرة للحافظ أبي عبدالله البرزالي، والتعريف بأجوبة الحافظ الب

... Show More
View Publication Preview PDF
Crossref
Publication Date
Sun Feb 28 2021
Journal Name
Journal Of Economics And Administrative Sciences
Identifying the leading sector in the Iraqi economy through the interrelationships between sectors - applied research
...Show More Authors

 

   Analyzing the size of the interrelationships between the main economic sectors in the Iraqi economy is an important necessity to know the impact of each sector on other economic sectors on the basis of the interrelationships and reciprocity between them, and what these relationships have achieved in terms of enhancing development and increasing the gross domestic product. To achieve the objectives of the study, we relied on mathematical (quantitative) analysis using user-product tables. Issued by the Ministry of Planning / Central Bureau of Statistics and Research (Directorate of National Accounts) for the economic sectors that make up the Iraqi economy. The study conc

... Show More
View Publication Preview PDF
Crossref
Publication Date
Wed Mar 31 2021
Journal Name
لارك
السيد الرئيس والغرانيق
...Show More Authors

  نقدم في هذا البحث تحليل لعملين أدبيين من منظور الحركات الطليعية ثبتت آثارها لدى بعض الكتاب العرب و أمريكا اللاتينية في فترة سنوات العشرينات والألفين.  كانت الحياة الخاصة للكاتب ميغيل انخل استورياس تلهمه أنتاج أعمال أدبية، اذ شغل منصب دبلوماسي وحصل على جائزة نوبل غواتيمالاكا. ولد وتوفى في مدينة غواتيملاكا   (1974- 1899)   يوجد تحول واضح في عمله ذات الشهرة السيد الرئيس(1948) الذي يكسر المعتاد، لأجل مست

... Show More
View Publication
Crossref
Publication Date
Wed Apr 09 2025
Journal Name
Journal Of The Iraqi University
La imprescindibilidad de la Exégesis en la Traducción del Texto Coránico
...Show More Authors

In the process of translating Qur’anic texts, there is an urgent need for interpretations of the Qur’anic text due to the presence of many incomprehensible Qur’anic verses or words because of our distance from the standard Arabic, language in which the Holy Qur’an was revealed, and the introduction of the foreign words into our language, in addition to the fact that many Qur’anic words are no longer used. All this prompted the need for the interpretation of the Qur'anic text, Therefore, it is necessary for the translator to resort to the books of interpretation if he intends to translate the Qur’an

View Publication Preview PDF
Publication Date
Fri Sep 30 2022
Journal Name
College Of Islamic Sciences
Shariah ruling on advice
...Show More Authors

Abstract

Research title: The legal ruling of advice.

This research deals with the topic of advice, as the research included the following:

Preamble: I explained in it the meaning of advice in the Qur’an and Sunnah, and that what is meant by it is a good performance of the duty, then explaining its importance, importing it, and the difference between advice and what is similar to it, from enjoining good, denial, reproach and reprimand, backbiting and the will.

The first topic: It dealt with the ruling on advice, whether it is recommended or disliked, or forbidden, because what is meant by it is to give advice to others may be an obligation in kind, or it may be desirable or dislike

... Show More
View Publication Preview PDF