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Assessment of systemic oxidative stress and antioxidants in Iraqi women with newly diagnosed and tamoxifen-treated breast cancer

Breast cancer (BC) is one of the most frequently observed malignancy in females worldwide. Today, tamoxifen (TAM) is considered as the highly effective therapy for treatment of breast tumors. Oxidative stress has implicated strongly in the pathophysiology of malignancies. This study aimed to investigate the changes in the levels of oxidants and antioxidants in patients with newly diagnosed and TAM-treated BC. Sixty newly diagnosed and 60 TAM-treated women with BC and 50 healthy volunteers were included in this study. Parameters including total oxidant capacity (TOC), total antioxidant capacity (TAC), and catalase (CAT) activity were determined before and after treatment with TAM. The serum levels of TOC and oxidative stress index (OSI) were elevated significantly (P<0.001) in newly diagnosed BC patients compared with control, while the level of TAC and CAT activity were observed to be statistically declined (P<0.001). Furthermore, the BC patients on TAM treatment have shown highly significant levels of serum TOC (P<0.05) and TAC (P<0.001) with a significant reduction (P<0.001) in CAT activity compared with control. In TAM-treated patients compared with newly diagnosed BC patients, the TOC level was decreased, the TAC level was increased, the OSI level was decreased and the CAT activity was decreased. The results indicate a strong and aggressive association between oxidative stress and the first onset of BC, as well as the tendency of TAM drug to improve the levels of TOC, TAC, and OSI in BC patients, but it had a reduction influence on CAT activity.

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Publication Date
Thu Nov 29 2018
Journal Name
Iraqi Journal Of Science
Application of WDR Technique with different Wavelet Codecs for Image Compression

     Storing and transferring the images data are raised in recent years due to requisiteness of transmission bandwidth for considerable storage capacity. Data compression method is proposed and applied in an attempt to convert data files into smaller files. The proposed and applied method is based on the Wavelet Difference Reduction (WDR) as considered the most efficient image coding method in recent years. Compression are done for three different Wavelet based Image techniques using WDR process. These techniques are implemented with different types of wavelet codecs. These are Daub2+2,2 Integer Wavelet transform, Daub5/3 integer to integer wavelet transform, and Daub9/7 Wavelet transform with level four. The used mu

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Publication Date
Sat Feb 26 2022
Journal Name
Iraqi Journal Of Science
Bifurcation Diagram of W(u_j;τ)-Function with (p,q)-Parameters

      This study aims to classify the critical points of functions with 4 variables and 8 parameters, we found the caustic for the certain function with the spreading of the critical points. Finally, as an application, we found the bifurcation solutions for the equation of sixth order with boundary conditions using the Lyapunov-Schmidt method in the variational case.

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Publication Date
Wed May 25 2022
Journal Name
Iraqi Journal Of Science
On Controllability of Impulsive Fractional Integro-differential Nonlocal System with State

      This paper is concerned with the controllability of a nonlinear impulsive fractional integro-differential nonlocal control system with state-dependent delay in a Banach space. At first, we introduce a mild solution for the control system by using fractional calculus and probability density function. Under sufficient conditions, the results are obtained by means of semigroup theory and the Krasnoselskii fixed point theorem. Finally, an example is given to illustrate the main results.

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Publication Date
Mon Oct 01 2018
Journal Name
Journal Of Economics And Administrative Sciences
For Sake of The Economic Reform - With some indication for Iraq

The imbalances and economic problems which it face the countries, it is a result of international economic developments or changes or global crises such as deterioration in trade, sharp changes in oil prices, increasing global indebtedness, sharp changes in foreign exchange rates and other changes, all that, they affect the economic features of any country. and These influences vary from one country to another according to the rigidity of its economy and its potential in maneuvering with economic plans and actions that would reduce the impact or avoidance with minimal damage. Therefore, the countries  that  suffer from accumulated economic problems as a result of mismanagement and poor planning or suffe

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Publication Date
Sun Mar 26 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
The Spectrophotometric Determination of Olanzapine via Coupling with Diazotized p-Nitroaniline

A new spectrophotometric method has been developed for the assay of olanzapine (OLN.) in pure and dosage forms. The method is based on the diazocoupling of (OLN.) with diazotized p-nitroaniline in alkaline medium to form a stable brown colored water-soluble azo dye with a maximum absorption at 405 nm.  The variables that affect the completion of reaction have been carefully optimized. Beer’s law is obeyed over the concentration range of (0.5-45.0 μg.mL-1) with a molar absorptivity of 1.5777×104 L.mol-1.cm-1.  The limit of detection was  0.3148  Î¼g.mL-1 and  Sandell’s  sensitivity value was 0.0198 μg.cm-2. The propose

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Publication Date
Tue Nov 19 2024
Journal Name
Journal Of Baghdad College Of Dentistry
Surface area measurements of upper dental cast with different final impressionss

Background : surface area anatomy is a proportional point to the retention of complete denture, in past there was no quantitative method to evaluate the surface area, nowadays the size and shape of maxillary arch is measured by different electronically and mathematical devices. A study was therefore, undertaken to measure surface area of upper dental cast that was taken by different final impressions. Materials and methods: twenty patients were examined. All of them had a healthy palate with no singe of injury, trauma, or deformity. Casts were taken by three different final impressions; zinc oxide, additional silicon, and poly ether. And two different devices were used; the computerized one and the Aluminum foil measure. Age, se

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Publication Date
Mon Jun 05 2023
Journal Name
Journal Of Engineering
Compressive Behavior of Fiber Reinforced Concrete Columns Rehabilitated with CFRP Warps

Over the last few years, there has been a worldwide increase in the use of composite materials for rehabilitation of deficient reinforced concrete structures. One important application of this technology is the use of Carbon Fiber Reinforced Polymer (CFRP) jacket to provide external confinement of reinforced concrete columns. Square concrete column specimens 100×100×1000 mm with concrete
compressive strength of about 30 and 50 MPa, steel fiber volume fraction 0%, 0.5%, 0.75%, and percentage of longitudinal reinforcement 2.01%, 3.14% and 4.52% were tested until failure in previous research. In this research seven tested columns were repaired and rehabilitated using one layer of CFRP flexible wraps and tested to determine their ultim

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Publication Date
Fri Jun 24 2022
Journal Name
Iraqi Journal Of Science
Comparison of Various Gradient Types for Biological Image with Morphological Operations

Biological image edge detection preserving the important structural properties in an image. Detecting accurate edges are very important for analyzing the basic properties associated with a biological image. Gradient operator plays very important role in edge detection. In this paper the images had been using are color biological images taken from microbiology laboratory at the biological department college of science Al-MustansiriyhUniversity and the effect of gradient operation have applied on around 10 different biological color images but view only two. In our proposed approach comparative of various gradient of biological image include (gradient of image, gradient of image using first order derivative edge detection (Soble,Prewitt,Ro

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Publication Date
Thu Nov 29 2018
Journal Name
Iraqi Journal Of Science
Application of WDR Technique with different Wavelet Codecs for Image Compression

FG Mohammed, HM Al-Dabbas, Iraqi journal of science, 2018 - Cited by 6

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Publication Date
Wed Dec 30 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Docking Study of Naringin Binding with COVID-19 Main Protease Enzyme

The Coronavirus Disease (COVID-19) has recently emerged as a human pathogen caused by SARS-CoV-2 virus was first reported from Wuhan, China, on 31 December 2019. Upon study, it has been used molecular docking to binding affinity between COVID-19 protease enzyme and flavonoids with evaluations based on docking scores calculated by AutoDock Vina. Results showed that naringin suppressed COVID-19 protease, as it has the highest binding value than other flavonoids including quercetin, hesperetin, garcina and naringenin. An important finding in this study is that naringin with neighboring poly hydroxyl groups can serve as inhibitors of COVID-19 protease bind to the S pocket of protein, it is shown that residues His163, Glu166, Asn142, His41and

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