Objectives: Osteoporosis (OP) is a systemic skeletal disorder characterized with bone mass loss and microstructure, resulting in fragility fractures. Continued secretion of Osteopontin (OPN), osteonectin (ON), osteocalcin (OCN), Parathyroid hormone (PTH) and Ca+2 lead to bone remodeling disorders, followed by bone loss and osteoporosis (OP). The current study aims to investigate the biochemical proteins OPN, OCN, and ON in postmenopausal women with osteoporosis and determine whether we could use them as good indicators for OP diagnostics. Materials and Methods: Case- control study carried out between December 2022 and July 2023. OP disease was confirmed among 108 Iraqi postmenopausal women randomly selected from different Iraqi hospitals, Baghdad, Iraq. Their ages ranged between 45 and 70 years. According to DEXA scan results 70 samples were OP +ve results, while 40 samples were -ve (healthy control). Blood samples collected from all participants in order to assess the levels of Ca+2, PTH, OPN, OCN, and ON by employing the ELISA technique. Results: High significant increase (P≤0.01) detected in PTH, OPN, and OCN serum levels, whereas, a significant decrease in Ca+² and ON, in OP patients as a comparison to control group. Conclusion: OPN, OCN, and ON measurements are accessible, inexpensive, and easy to use and could be considered a good indicators for OP diagnostics; beside to a DEXA scan as a sensitive monitoring indicator for early detection of osteoporosis.
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Breast cancer is the commonest cause of cancer related death in women worldwide. Amplification or over-expression of the ERBB2 (HER/neu) gene occurs in approximately 15-30% of breast cancer cases and it is strongly associated with an increased disease recurrence and a poor prognosis. Determination of HER2/neu status is crucial in the treatment plan as that positive cases will respond to trastuzumab therapy. It has been used to test for HER2/neu by immunohistochemistry as a first step and then to study only the equivocal positive cases (score 2+) by in situ hybridization technique. The aim of our study is to compare between immunohistochemistry and silver in situ hybridization (SISH) in assessment of human epidermal growth factor (HER2/neu)
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Objective: To assess two kinds of extraction (aqueous and methanolic) for Calendula officials using flowers, leaves
and stems and studying their antibacterial activity against five different bacteria.
Methodology: Calendula officials were selected to carry out this study. Flowers, leaves and stems were collected from
local markets in Baghdad then dried in shade for 7 days and grinded to fine powder. Aqueous hot extracts for 2hr. at
(100c˚) and alcoholic extracts for 48 hrs at (80c˚) were performed using flowers, leaves and stems then studied
antibacterial effect against five different bacterial genuses by using well diffusion technique.
Results: This study showed that hot aqueous extracts for 2hr. to all parts of Cale
Abstract: The aim of this study was to evaluate the effect of bone density value in Hounsfield unit derived from cone beam computed tomography (CBCT), and implant dimensions in relation to implant stability parameters namely the resonance frequency analysis and the insertion torque (IT) value. It included 24 patients who received 42 dental implants (DI). The bone density of the planned implant site was preoperatively measured using cone beam computed tomography. The implant stability was measured using Osstell implant stability quotient (ISQ). The ISQ values were recorded immediately postoperatively and after 16 weeks. The IT value was categorized as 35 N/cm or > 35 N/cm. The mean (standard deviation) primary stability was 79.58 (5.27) ISQ,
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Wasit Governorate is characterized by industrials activities such as groups of asphalts and bricks factories, oil fields and thermal power plant, in addition to the agricultural activity that is widely separated, which leads to pollution of the surface soils with heavy metals. The main objective in this research is to assess heavy metals pollution and understand the distribution in the surface soils in the studied area. Twenty two surface soils samples were collected from 6 districts and 4 subdistricts within Wasit Governorate during April 2017. The results obtained showed that grain size analyzes are classified as sandy mud (sand 9.5%, silt 50.8 % and clays 39.8%). In the term of geochemic
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