Background: The study's objective was to estimate the effects of radiation on testosterone-related hormones and blood components in prostate cancer patients. N Materials and Method: This study aims to investigate the effects of radiation on 20 male prostate cancer patients at the Middle Euphrates Oncology Centre. Blood samples were collected before and after radiation treatment, with a total dose of 60- 70 Gy, The blood parameters were analyzed. The hospital laboratory conducted the blood analysis using an analyzer (Diagon D-cell5D) to test blood components before and after radiation. Hormonal examinations included testosterone levels, using the VIDASR 30 for Multiparametric immunoassay system Results: The study assessed the socio-demography of prostate cancer male patients, revealing that the majority were aged 69.55 t 10.76 years, with a weight of 75.3 t 10.84 Kg and height of 170.50 t 8.70 cm. The stage of cancer was assessed, with 25% of patients being IV and IIV, followed by II, IB, and V. Only one patient was at stage III. The Gleason Score (GS) was used to classify patients, with 40% being given a score of 7, followed by 6, 8, and 9 equally (20%). Total Prostate-specific Antigen (PSA) had a mean value of 12.87 t 2.78. Hematological analysis showed a significant decrease in random blood sugar levels, white blood cells, lymphocytes platelets, and hemoglobin levels after radiotherapy. Testosterone levels also declined after radiotherapy fractions. However, kidney functions like urea and creatinine levels increased after pelvic irradiation Conclusion: The study found that radiation treatment for prostate cancer significantly impacted blood components and hormones associated with testosterone. It led to reduced levels of random blood sugar, white blood cells, lymphocytes, platelets, haemoglobin, and testosterone. Additionally, high-energy therapeutic x-rays increased_ levels of urea and creatinine, indicating the need for strict monitoring and management of adverse effects.
Objective : Multiple sclerosis (MS) is a common neurological disease deeply linked with the immune-inflammatory disorders whereas the term (multiple) mostly refers to the multi-focal zones of Inflammation caused by lymphocytes and macrophages infiltration besides oligodendrocytes death. Accordingly , the dysfunctional immune system able to damage myelin ( a pivotal component of the central nervous system ) which responsible for communication among neurons. The aim of the present study is to innovate a biochemical relationship between MS and thyroid hormones (THs) by highlighting immunological responses and also to examine the action of Interferon beta (IFNβ) drug on thyroid hormone (THs) and thyroid stimulation hormone (TSH). Materials and
... Show MoreBreast cancer is the commonest cancer affecting women worldwide. Different studies have dealt with the etiological factors of that cancer aiming to find a way for early diagnosis and satisfactory therapy. The present study clarified the relationship between genetic polymorphisms of BRCA1 & BRCA2 genes and some etiological risk factors among breast cancer patients in Iraq. This investigation was carried out on 25 patients (all were females) who were diagnosed as breast cancer patients attended AL-Kadhemya Teaching Hospital in Baghdad and 10 apparently healthy women were used as a control, all women (patients and control) aged above 40 years. The Wizard Promega kit was used for DNA isolation from breast patients and normal individuals. B
... Show MoreNon-thermal plasma(Dielectric barrier discharge) has many uses including living tissue sterilization, inactivation of the bacteria, excimer formation, angiogenesis, and surface treatment. This research aim is to use cold plasma as a tool to search the effect of the dielectric barrier discharge system at room temperature on human sperm motility and DNA integrity. This work was performed on 60 human semen samples suffering from low motility; each sample was prepared by centrifugation method, then each semen sample was divided into two sections, the first section is before significant exposure to the plasma system (DBD) and the second section is after treatment with the DBD system at ambient temperature. Before and after exposure to non-the
... Show MoreThe dependence of the cross-section of the coherent and incoherent radiation peaks in the X-ray absorption experiment of different energies (20-800 Kev) was investigated. Cross-sectional dependence on the atomic number Z was included from the published data for (8) elements, ranging from carbon to silver (C-Ag). The proportional constant K was obtained between (σc/σi), with the atomic number Z from (6-47). The results show that the value of K exponentially changes with energy.
This study assesses the delay of mastectomy "time from the first consultation of a doctor to the time of mastectomy" and its relationship with the stage of the disease among Iraqi women with breast cancer. A study was carried out on (113) women who were referred to the Outpatient Clinic of the Oncology Teaching Hospital and the Iraqi National Cancer Research Center, University of Baghdad, for the period from 2012 to 2016.Patients' age range between (40-49) years comprised (60.2%) of cases, and showed advanced tumor stage (62.96%)of stage III. It was found that infiltrating ductal carcinoma was the most common type of breast cancer that found in (77%) of cases.
Mostly there was no delay of mastectomy for more than one month delay
... Show MoreChemiluminescenc (CL), light emitted during chemical reaction, is one of the accurate methods used to detect directly oxygen free radicals. In this study, luminol was used as CL detector, to detect the concentration of free radicals formed in whole blood exposed to high power microwave pulses. The changes in the intensity of CL signal gives a clear relation between the concentration of free radicals formed by radiation in blood and changes in blood properties such as hemolysis of blood cells. This is done by measuring the electrical sytoplsimic electrical properties, the results are substituted in Maxwell-Wagner equation, to obtain electrical conductivity of cytoplasm, which is 18.3 ms/cm, while at suspension med
... Show MoreNew chelating ligand derived from triazole and its complexes with metal ions Rhodium, Platinum and Gold were synthesized. Through a copper (I)-catalyzed click reaction, the ligand produced 1,3-dipolar cycloaddition between 2,6-bis((prop-2-yn-1-yloxy) methyl) pyridine and 1-azidododecane. All structures of these new compounds were rigorously characterized in the solid state using spectroscopic techniques like: 1HNMR, 13CNMR, Uv-Vis, FTIR, metal and elemental analyses, magnetic susceptibility and conductivity measurements at room temperature, it was found that the ligand acts as a penta and tetradentate chelate through N3O2, N2O2, and the geometry of the new complex
... Show MoreNew chelating ligand derived from triazole and its complexes with metal ions Rhodium, Platinum and Gold were synthesized. Through a copper (I)-catalyzed click reaction, the ligand produced 1,3-dipolar cycloaddition between 2,6-bis((prop-2-yn-1-yloxy) methyl) pyridine and 1-azidododecane. All structures of these new compounds were rigorously characterized in the solid state using spectroscopic techniques like: 1HNMR, 13CNMR, Uv-Vis, FTIR, metal and elemental analyses, magnetic susceptibility and conductivity measurements at room temperature, it was found that the ligand acts as a penta and tetradentate chelate through N3O2, N2O2, and the geometry of the new complexes are identified as octahedral for (Rh & Pt) complexes a
... Show MoreThe effect of 0.66 µeV gamma radiation on the structural and optical properties of the CdTe thin films prepared by thermal evaporation at thickness 350nm, The samples were irradiated with time (50 h and 79h) at room temperature. The absorption spectra for all the samples were recorded using UV-VIS spectrometer in order to calculate the energy gap, refractive index and others parameter . The optical energy gap was found decrease from (1.9 to 1.67) eV.
The effects of solar radiation pressure at several satellite (near Earth orbit satellite, low Earth orbit satellite, medium Earth orbit satellite and high Earth orbit satellite ) have been investigated. Computer simulation of the equation of motion with perturbations using step-by-step integration (Cowell's method) designed by matlab a 7.4 where using Jacobian matrix method to increase the accuracy of result.