This study aimed to evaluate the anticancer activity and cell division arresting by dandelion methanolic extract on breast cancer cell line MCF-7 cancer cell line. For achieving this goal, cytotoxicity assay (MTT assay), multipara system assay: High Content Screening (HCS) which include (viable cell count VCC; membrane permeability MP; cellular mitochondrial permeability CMP; nuclear intensity NI and cytochrome C releasing ), reactive oxygen species detection and cell cycle phases division were tested. The results of this study showed the ability of the plant to reduce cancer cell viability in a dose-dependant manner within IC50 (141.0) in comparison to IC50 of (334.4) on the

: Partial purification of phosphoenolpyruvate carboxykinase (PEPCK) from type 2 diabetic patients sera take place using some purification steps such as participation with ammonium sulphate (55-80%) and filtered through dialysis, then ion exchange chromatography by DEAE sepharose anion column, gel filtration chromatography by sephadex G-100 column. In ion exchange step, there are four peak are obtained, the highest enzyme activity obtained by (0.4 M Nacl) with purification fold (2.18), yield (44.3) of enzyme and specific activity (13.5) mg/ng, which obtained a single peak by gel filtration chromatography, the degree of purification (5.34) fold, yield of enzyme (20%) with specific activity (33.109mg/ng). The purified enzyme had an optimum tem

The purpose of this research is to synthesize a new mixed ligand Schiff base complexes of Co(II),Ni(II),Cu(II), Zn(II), Cd(II), and Hg(II),which are formulated from the Schiff base (L) that resulted from orthophathalaldehyde (2-PA) with 4-chloroaniline(4-NA). Diagnosis of prepared Ligand and its complexes is done by spectral methods as 1H–NMR, mass spectrometer, FTIR, UV-Vis, molar conductance, elemental microanalyses, atomic absoption and magnetic susceptibility. The analytical studyofall new complexes has shown octahedral geometries. Organic performance study of ligand Schiff base and its complexes reveals different activities agansit four types of bactria; two gram (+) and two gram (-) .

   This research includes the application of non-parametric methods in estimating the conditional survival function represented in a method (Turnbull) and (Generalization Turnbull's) using data for Interval censored of breast cancer and two types of treatment, Chemotherapy and radiation therapy and age is continuous variable, The algorithm of estimators was applied through using (MATLAB) and then the use average Mean Square Error (MSE) as amusement  to the estimates and the results showed (generalization of Turnbull's) In estimating the conditional survival function and for both treatments ,The estimated survival of the patients does not show very large differences

Pt (IV) complexes were synthesized from 4-Aminoantipyrine (4-AAP) as a primary ligand, and sodium pyrophosphate as a secondary ligand using metal: ligand in (1:1) mole ratio with molecular formula [Pt (4-AAP)Cl4],[Pt (4-AAP)(Pyph)Cl2]. These complexes were characterized by elemental microanalysis (C.H.N), (A.A), [I.R, (U.V–Vis), mass spectroscopy], along with molar conductivity, chloride contents and melting point measurements. The ligands (4-AAP) and (Pyph) gave octahedral geometry with Pt (IV) rapid, simple, sensitive and validated spectrophotometric method has been described for the determination of platinum (IV) using 4-aminoantipyrine. The complex product was quantitatively measured at 385nm and the reaction conditions were studie

In this paper some chalcones (C1-C8) are prepared based on the reaction of one mole of substituted acetophenone with one mole of substituted benzaldehydes in the presence of (40%) sodium hydroxide as a base. Pyrazolines (P1–P8) are prepared from the reaction of chalcones (C1-C8) with hydrazine hydrate. Isoxazoline (I1-I8) is prepared from the reaction of chalcones (C1-C8) with hydroxyl amine hydrochloride in the presence of (10%) sodium hydroxide as a base. These compounds are characterized by using various physical and spectral methods. The compounds are screened for their in vitro antibacterial activity using gram-positive bacteria and gram-negative bacteria. Several derivatives of pyrazolines and isoxazolines are produced well to moder