Preferred Language
Articles
/
Xxe4jJIBVTCNdQwCCbbp
SYNTHESIS OF NEW PROPRANOLOL DERIVATIVES AS POSSIBLE PRODRUGS
...Show More Authors

Propranolol is a nonselective-adrenergic blocker used in the treatment of hypertension, cardiac arrhythmias, and angina pectoris. A significant problem in propranolol therapy is that it undergoes extensive presystemic metabolism after oral administration leading to reduced bioavailability. In this study, two new propranolol derivatives have been designed, synthesized and characterized. These compounds were formed by acylation of propranolol followed by nucleophilic substitution reaction of acylated propranolol, these derivatives were analyzed for IR, CHN, melting points, and evaluated for their lipophilic properties compared with propranolol. The lower partition coefficient of these two derivatives revealed that the prodrug approach may be an effective means of avoiding first- pass metabolism.

Publication Date
Tue Mar 28 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Formulation of Azithromycin Suspension as an Oral Dosage Form
...Show More Authors

Azithromycin is the drug of choice in the treatment of several bacterial infections, most often those causing middle ear infection, bronchitis, pneumonia, typhoid and sinusitis. It’s also effective against certain urinary tract infections and venereal diseases. This study was carried out to prepare an acceptable suspension either as dry physical mixture powder or granules to be reconstituted, through studying the effect of various type and concentration of suspending agent (xanthan gum, hydroxypropyl methylcellulose (HPMC), either alone or in combination) on the release profile of the drug. The best prepared suspension formulas (H& III) were selected depending on the dissolution profile of each formulas and then compared with

... Show More
View Publication Preview PDF
Crossref (1)
Crossref
Publication Date
Tue Jun 15 2021
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Formulation and Characterization of Felodipine as an Oral Nanoemulsions
...Show More Authors

            Felodipine is a calcium-channel blocker with low aqueous solubility and bioavailability. Lipid dosage forms are attractive delivery systems for such hydrophobic drug molecules. Nanoemulsion (NE) is one of the popular methods that has been used to solve the dispersibility problems of many drugs. Felodipine was formulated as a NE utilizing oleic acid as an oil phase, tween 80 and tween 60 as surfactants and ethanol as a co-surfactant. Eight formulas were prepared, and different tests were performed to ensure the stability of the NEs, such as particle size, polydispersity index, zeta potential, dilution test, drug content, viscosity and in-vitro drug release. Result

... Show More
View Publication Preview PDF
Scopus (14)
Crossref (5)
Scopus Crossref
Publication Date
Thu Apr 01 2021
Journal Name
Iop Conference Series: Earth And Environmental Science
Disadvantages of using Nano-particles as fertilizers in Iraq
...Show More Authors
Abstract<p>The agriculture around the world faced many difficulties and the important was to reduce inputs of chemical fertilizers and pesticides and increase the total yield specially with the continuous grow of populations numbers at the world expected to reach more than 9 billion by 2050. In other hand there are other problems which make the challenges bigger such as wars, biotic and abiotic stress, and diseases. The scientists tried to find solutions by using Nano-fertilization which consider a modern way to quickly grow up the yield and decrease use the chemicals. The use of nanotechnology may be destructive on human and the environment due to fast accumulation in the tissues of alive bodie</p> ... Show More
View Publication
Scopus (8)
Crossref (6)
Scopus Crossref
Publication Date
Fri Jan 01 2021
Journal Name
Water Pollution And Management Practices
Existence of Antibiotics in Wastewater as a Pollution Indicator
...Show More Authors

View Publication
Scopus (2)
Crossref (3)
Scopus Crossref
Publication Date
Thu Jun 25 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Formulation and Evaluation of Iornoxicam as Dissolving Microneedle Patch
...Show More Authors

The objective of the study was to develop microneedle (MN) patch, with suitable properties to ensure the delivery of a therapeutic level of lornoxicam (LXM) in a period suitable to replace parenteral administration in patients, especially those who fear needles. The used polymers were cold water-soluble polyvinyl alcohol (PVA) and polyvinylpyrrolidone (PVP) of low molecular weight with PEG 400 as plasticizer and Tween 80 (to enhance the release) using micro molding technique. Patches were studied for needle morphology, drug content, axial fracture force measurement and drug release while the optimized formulas were further subjected to pH measurement, folding endurance, ex vivo permeation study, histopathology study, stability study and

... Show More
View Publication Preview PDF
Scopus (9)
Crossref (3)
Scopus Crossref
Publication Date
Fri Aug 09 2024
Journal Name
Theory And Practice In Language Studies
Fallacy as a Strategy of Argumentation in Political Debates
...Show More Authors

This study aims to study argumentation in political debates by figuring out the logical fallacies employed in the debates of Clinton and Trump, the presidential nominees of the 2016 elections, and Biden and Trump, the leading contenders in the 2020 United States presidential election. The study attempts to answer the questions: (1) What relevance fallacies are adopted in the debate between Trump and Clinton? (2) What rhetorical devices are used to influence the audience and gain voters besides fallacies in the debates selected? The study analyses two texts from two arguments using Damer's (2009) taxonomy of relevance fallacy and rhetorical devices based on Perrine’s (1969) model of communication and interpersonal rhetoric to answe

... Show More
View Publication Preview PDF
Scopus Crossref
Publication Date
Thu Mar 01 2012
Journal Name
International Journal Of Innovative Computing, Information And Control
ITTP: A new transport protocol for VoIP applications
...Show More Authors

View Publication
Scopus (14)
Scopus
Publication Date
Wed Dec 31 2014
Journal Name
Iraqi Journal For Computers And Informatics
Gate Control System for New Iraqi License Plate
...Show More Authors

This paper presents an approach to license plate localization and recognition. A proposed method is designed to control the opening of door gate based on the recognition of the license plates number in Iraq. In general the system consists of four stages; Image capturing, License plate cropping, character segmentation and character recognition. In the first stage, the vehicle photo is taken from standard camera placed on the door gate with a specific distance from the front of vehicle to be processed by our system. Then, the detection method searches for the matching of the license plate in the image with a standard plate. The segmentation stage is performed by is using edge detection. Then character recognition, done by comparing with templ

... Show More
View Publication Preview PDF
Crossref (1)
Crossref
Publication Date
Fri Mar 19 2021
Journal Name
Periodicals Of Engineering And Natural Sciences (pen)
New cost control techniques in mega construction projects
...Show More Authors

View Publication
Scopus (3)
Crossref (1)
Scopus Crossref
Publication Date
Sun Nov 12 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
New Taxa For Trachomitum Woodson (Apocynaceae) in Iraq
...Show More Authors

The present study includes a morphological investigation to

the plant specimens of the genus Trachomitum which assembling by one species in Iraq it is T  venetum (L.) Woodson. The specimens in

the Iraqi herbaria and that which is collected for the first time from new locations. After a detail  and specific investigation for all the

characteristic features, and according to the obvious variations between different parts of the plants we can identify the specimens of the   species  .T venetum   into  three  subspecies  which  are  subsp. armenum, subsp. scabrum and subsp. sarmatiense .

... Show More
View Publication Preview PDF