In present days, drug resistance is a major emerging problem in the healthcare sector. Novel antibiotics are in considerable need because present effective treatments have repeatedly failed. Antimicrobial peptides are the biologically active secondary metabolites produced by a variety of microorganisms like bacteria, fungi, and algae, which possess surface activity reduction activity along with this they are having antimicrobial, antifungal, and antioxidant antibiofilm activity. Antimicrobial peptides include a wide variety of bioactive compounds such as Bacteriocins, glycolipids, lipopeptides, polysaccharide-protein complexes, phospholipids, fatty acids, and neutral lipids. Bioactive peptides derived from various natural sources like bacteria, fungi, and algae in higher eucaryotic animals offer novel possibilities to identify potential lead compounds for treating a variety of diseases. The antimicrobial activity, various properties, mechanisms, and applications of AMPs are the focus of this systematic study.
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This review covers recent progress in the synthesis of curcumin and the bioactivity of semisynthetic and synthetic analogs of curcumin. The review also shows how curcumin is a useful intermediate for the synthesis of more complex organic molecules; historical perspective; the process of preparing the metal complexes and characterization the produced complexes using various spectral and other techniques; shows the importance of curcumin and its derivatives for their potential applications in medical devices and broad-spectrum of medical application such as antibiotic ointment, alternative therapeutics, antifungal, and antibacterial activities
MT Suhail, SA Hussein, MN Abdulhussein, WQ Abdaullateef, M khairallah Aid…, Migration Letters, 2024
In this review, previous studies on the synthesis and characterization of the metal Complexes with paracetamol by elemental analysis, thermal analysis, (IR, NMR and UV-Vis (spectroscopy and conductivity. In reviewing these studies, the authors found that paracetamol can be coordinated through the pair of electrons on the hydroxyl O-atom, carbonyl O-atom, and N-atom of the amide group. If the paracetamol was a monodentate ligand, it will be coordinated by one of the following atoms O-hydroxyl, O-carbonyl or N-amide. But if the paracetamol was bidentate, it is coordinated by atoms (O-carbonyl and N-amide), (O-hydroxyl and N-amide) or (O-carbonyl and O-hydroxyl). The authors also found that free paracetamol and its complexes have antimicrobial
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This review explores the Knowledge Discovery Database (KDD) approach, which supports the bioinformatics domain to progress efficiently, and illustrate their relationship with data mining. Thus, it is important to extract advantages of Data Mining (DM) strategy management such as effectively stressing its role in cost control, which is the principle of competitive intelligence, and the role of it in information management. As well as, its ability to discover hidden knowledge. However, there are many challenges such as inaccurate, hand-written data, and analyzing a large amount of variant information for extracting useful knowledge by using DM strategies. These strategies are successfully applied in several applications as data wa
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Abstract
Back ground: Renal cell carcinoma is an uncommon condition that develops during pregnancy. Due to a lack of conventional norms and a dearth of literature, its management is a serious issue.
Case presentation: We will discuss a case study of a twenty-year-old female girl who is pregnant G1 P1 A0, has had five missing periods (20 weeks gestation), and has frank hematuria due to a massive, incidentally detected renal cell carcinoma. We also go through the current guidelines for treating kidney malignancies during pregnancy, as well as the imaging studies that are now available.
Conclusion: Although the best time for surgery is debatable, a mult
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