To determine the relationship between Helicobacter pylori infection and skin disorders, sixty six patients who suffering from skin diseases include chronic urticarial (CU) and atopic dermatitis (AD) who attended at Dermatological Clinic/ Al-Numan Teaching Hospital from the beginning of October 2015 to the end of January 2016 with age (6-62) have been investigated and compared to twenty two samples of apparently healthy individuals were studied as control group. All the studied groups were subjected to measurement of antiHelicobacter pylori IgG antibodies by enzyme linked immuno sorbent assay (ELISA) and detection of 16S rRNA and CagA genes by using singleplex and multiplex PCR methods. The results of current study revealed that there was a highly significant elevation (P<0.01) in concentration of H. pylori IgG antibodies in sera of the CU and AD patients compared with control group, also the results revealed that there was a significant elevation (P<0.05) in concentration of H. pylori IgG antibodies in sera of the CU patients compared with control group, and significant elevation (P<0.05) in concentration of H. pylori IgG antibodies in sera of AD patients compared with control group. The results of present study indicated that 26(66.67%) patients out of 39 CU patients were positive for both of 16S rRNA and CagA genes, while 13(33.33%) patients out of 39 CU patients were negative for those genes. Also, the results revealed that 19(70.37%) patients out of 27 AD patients were positive for both of 16S rRNA and CagA genes, whereas only 8(29.62%) were negative for both those genes comparing with control group which showed 1(4.54%) individuals out of 22 apparently healthy individuals were positive for both 16S rRNA and CagA genes, the statistical analysis was highly significant (P<0.01).
Back ground: Visceral leishmaniasis is an endemic protozoan disease in Iraq. Recovery from this disease confers a solid and permanent immunity. Immunological assessment of our patients was carried out and the results showed a significant reduction in the percentage of CD3, CD56 and a significant increase in the percentage of CD19 in the peripheral blood lymphocyte of VL in comparison with control group.
Patients and methods: Indirect immunofluorescence technique analysis was performed to detect the percentage of CD3, CD19and CD56 positive lymphocytes.
Results: Our results in the patients groups showed decrease in the percentage of CD3, CD56 and increase in the percentage of CD19. Follow up of patients after
Rheumatoid arthritis and periodontitis use analogous effector destructive procedures, in that the inflammatory cells and pro-inflammatory cytokines that drive chronic bone erosion in RA and chronic periodontal destruction in Periodontitis are alike. Periodontitis (PD) has appeared as a hazard factor in a number of health situations as rheumatoid arthritis (RA). To determine the effect of anti-tumor necrosis factor alpha biological treatment (methotrexate and Enbrel or infliximab) on periodontal status of patients having rheumatoid arthritis with periodontitis in comparison to those having periodontitis without rheumatoid arthritis and control healthy subjects and to determine the serum levels of anti-cyclic citrullinated peptide (ACCP) in t
... Show MoreBackground: Renal disease results in significant disorder of hemostasis (bleeding diathesis or
hypercoagulable state).
Objectives: This study is to determine the changes in some hemostasis parameters in patients with
chronic renal failure and identify the effect of dialysis on these changes.
Patients and Methods: seventy five patients with end stage chronic renal failure were collected from
Baghdad hospital, a full detailed history and clinical examination were performed, 50 patients were on
maintenance weekly hemodialysis, and 25 patients were without dialysis.
Result: Bleeding time was significantly higher in patients with chronic renal failure who didn’t need
any type of dialysis, positive D-Dimer test. In so
Background: Epstein Barr Virus (EBV) infection has been implicated in pathogenesis of several types of carcinomas such as nasopharyngeal carcinoma, gastric cancer and bladder cancer and has recently been associated with breast cancer.
Objective: To evaluate the relations between Epstein Barr virus-encoded small RNA (EBER) and breast cancer.
Methods: Twenty two cases of breast cancer were retrieved from the Al-Kadhimiya Teaching Hospital in Baghdad. Clinical data were analyzed from the medical records and formalin fixed, paraffin embedded tumor tissue were examined by Chromogeneic in situ hybridization (ISH) technique for the detection of EBER.
Results: The expression of EBER in tissues patients with breast cancer in the present
plaque forming assay was used enumerate the number of plaque forming cells of anti-HBc in eight patintes with chronic hepatitis and eight health
Background: CHOP regimen was the standard treatment for patients with diffuse large and mixed cells Non-Hodgkin's lymphoma (NHL) even in comparison with second and third generation regimen. Recently Rituximab –CHOP is considered the standard treatment for aggressive B-cell NHL while CHOP (alone) is so for aggressive T-cell NHL, yet more than one study investigates another regimen which is VACOP-B and some showed its superiority over CHOP. Prior to the introduction of Rituximab, we used VACOP-B in the treatment of high &intermediate grade NHL in adult Iraqi patients as an alternative to CHOP.
Patients and Methods:We performed a prospective analysis of 20 adult patients who, between April 2000 and October2005, received VACOP-
Background: Early detection of subclinical left ventricular (LV) systolic dysfunction is crucial and could influence patients' prognosis by aiding the clinician to candidate patients for better management.
Objective: To detect early LV systolic dysfunction in asymptomatic patient with chronic aortic regurgitation by two dimensional speckle tracking echocardiography.
Methods: Sixty one asymptomatic patients with chronic aortic regurgitation, with no ischemic heart diseases (by coronary angiography) or conductive heart diseases, no diabetes mellitus, no hypertension, and no other valvular heart diseases (group 1) and fifty age and sex-matched healthy subjects (
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Chronic renal failure (CRF) is progressive irreversible destruction of kidney tissue by disease which, if not treated by dialysis or transplant, will result in patient's death. This study was carried out on 30 patients (17 male and 13 female) with chronic renal failure. The aim of this research was studied the changes in the level of total protein ,albumin, calcium ,ionized calcium, phosphorous , iron ,ALP, LDH ,CK and FFA in patients with CRF before and after hemodialysis .The obtained results have been compared with 30 healthy subjects as control group (18male and 12 female). The results showed that there was significant increase in the level of calcium ,ionized calcium, phosphorous ,iron ,ALP,LDH,CK and FFA ,while there was a signifi
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Background: Multiple myeloma is characterized by clonal expansion and accumulation of abnormal plasma cells in the bone marrow compartment. This study was conducted to determine the frequency and hematological presentation of multiple myeloma in Nanakaly Hospital in Erbil city.
patients and Methods: This descriptive retrospective study was carried out at Nanakaly Hospital over a period of six years from January 2007 to August 2012. A total of 109 patients who were diagnosed with multiple myeloma all were included to analyze the clinical and laboratory profiles. All patients were selected based on preset diagnostic criteria by the WHO.
Results: The study showed a male: female ratio of 1:1.1, the mean age of male patients was 57.8 ye
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Chronic kidney disease (CKD) is a permanent loss of kidney function which is diagnosed when the glomerular filtration rate (GFR) is under 60 ml\min\1.73m2 for more than three months. The present study was conducted at Kidney Transplant and Dialysis Center in the Medical City in Baghdad from October 2018 to April 2019. Sixty CKD patients with an age ranged of 40 to 65 years and 25 healthy subjects were involved in this study. Blood samples were collected to evaluate the levels of kidney function parameters and thyroid hormones. The levels of urea, creatinine and uric acid showed highly significant (p ≤ 0.01) increases in CKD patient in comparison with the control group, while the values of GFR and creatinine clearance showed highly
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