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Effect of Thyroid Hormone Abnormalities on Hemoglobin A1c in Hemodialysis Patients Taking Erythropoietin

Abstract Background Hemoglobin A1c (HbA1c) is a widely used test for glycemic control. It is done for chronic kidney disease (CKD) patients. Renal disease is accompanied by thyroid abnormalities, which affect HbA1c, especially in those taking erythropoiesis-stimulating agents (ESAs). We aimed to find the effect of thyroid dysfunction on HbA1c in hemodialysis patients taking ESAs and those who do not. Materials and Method Fifty six patients were included in this study, which was done between September 2017 and June 2018, in Baghdad Teaching Hospital. Thyroid stimulating hormone, free T3, free T4 and HbA1c measurements were done. The patients were divided into 2 groups; those who took ESAs and those who did not, then they were subdivided into those with hypothyroidism and hyperthyroidism according to the Body mass index (BMI). Results Comparing HbA1c levels in hemodialysis patients taking ESAs and those who did not, showed no significant difference (5.79 ± 1.91 vs. 6.19 ± 1.64, P=0.09). The difference was also not significant in both hypothyroid and hyperthyroid patients in both high and low BMI patients. The only significant difference in HbA1c was between hyperthyroid and hypothyroid patients in those not taking ESAs, and having low BMI (4.97 ± 1.36 and 7.51 ± 0.87 respectively, P=0.02). Conclusion There is no significant influence of thyroid hormone changes on HbA1c levels in hemodialysis patients taking and not taking ESAs. Keywords Hemoglobin A1c, Chronic kidney disease, Thyroid dysfunction, Hemodialysis, Erythropoiesisstimulating agents.

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Publication Date
Sun Oct 02 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
The impact of inflammation on Resistin, Insulin and Troponin I in Acute Myocardial Infarction patients

Background: Myocardial Infarction (MI) is most commonly due to occlusion (blockage) of a coronary artery following the rupture of a vulnerable atherosclerotic plaque. It has been suggested that the adipose tissue may play an important role in mediating this chronic inflammatory process. Inflammatory responses are involved in the initiation and progression of atherosclerotic plaques. Resistin is a cysteine-rich polypeptide that is expressed at relatively lower levels in human adipocytes but higher levels in macrophages. Insulin is an important hormone as it regulates the level of glucose, in the blood. This protein is formed in specialized cells of the pancreas called beta islet cells.
Subjects and Methods:The study included 50 patient

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Publication Date
Thu Dec 31 2009
Journal Name
The Iraqi Journal Of Veterinary Medicine
Possible beneficial effects of amlodipine, lisinopril, and their Combination on lipid profile in hypertensive patients

It is well known that monotherapy does not provide therapeutic response in all hypertensive. Somepatients show an excellent response, while in others there is a poor response. Combinationantihypertensive therapy is administered when blood pressure is inadequately controlled bymonotherapy to achieve a balanced and additive antihypertensive effect with minimum adverse effects.Both angiotensin converting enzyme (ACE) inhibitors and dihydropyridine type of calcium antagonistsare well established and widely used in monotherapy. An understanding of differences in themechanism of action of these agents allows a logical approach for the use of these agents as acombination therapy. This study was designed to evaluate the possible beneficial

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Publication Date
Fri Dec 30 2011
Journal Name
Al-kindy College Medical Journal
Sensorineural Deafness Among Patients with Chronic Renal Failure in Al-kindi Teaching Hospital

Background: Patients with chronic kidney
disease have different grades of sensorineural
deafness .
Objective: To study the incidence of
sensorineural hearing loss and possible contributing
factors in patients with chronic kidney disease.
Methods: A total of 100 patients with chronic
kidney disease were studied. All of them were
males. 92 of them were on regular haemodialysis
programme. Only 8 patients were on conservative
management the age range of the study patients was
18-40 year patients were divided into three groups
according to age. All patients were assessed
clinically and were evaluated by audiometry , and
analysis was made on bone conduction threshold
.The mean follow up period was 2

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Publication Date
Mon Oct 01 2012
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Hepatitis C Virus among Iraqi Patients on Renal Dialysis, Some Immunological Profiles

Back ground: Chronic hepatitis C (HCV) is the most common chronic liver disease at present, and HCV infection is found with variable prevalence in dialysis populations in different parts of the world.
Objective: The aim of this study was to determine the concentration of sialic acid and immunoglobulins level in the sera of patients with chronic renal failure whom infected with Hepatitis C virus, and the effect of hemodialysis on them.
Patients&Methods: Regarding to this aim, total sialic acid levels (TSA) and immunoglobulins level were studied on the blood samples of 20 patients with chronic renal failure + Hepatitis C virus (positive group) and 20 patients with chronic renal failure (negative group) and 20 healthy volunteers.

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Publication Date
Sat Jun 15 2019
Journal Name
Journal Of Baghdad College Of Dentistry
Taste Detection Thresholds in Relation to Salivary and Serum Zinc in Patients on Simvastatin Treatment

Background: Hyperlipidemia is an elevated fat (lipids), mostly cholesterol and triglycerides, in the blood. These lipids usually bind to proteins to remain circulated so-called lipoprotein. Aims of the study: To determine taste detection threshold and estimate the trace elements (zinc) in serum and saliva of those patients and compare all of these with healthy control subjects. Methods: Eighty subjects were incorporated in this study, thy were divided into two groups: forty patients on simvastatin treatment age between (35-60) years, and forty healthy control of age range between (35-60) years. Saliva was collected by non-stimulated technique within 10 minutes. Serum was obtained from each subject. Zinc was estimated in serum and saliva

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Publication Date
Thu Nov 01 2018
Journal Name
Iraqi National Journal Of Nursing Specialties
Impact of functional disability on lifestyle for patients with arthritis


A descriptive study, which was using an assessment approach, was conducted for the
determination of the impact of rheumatoid arthritis and osteoarthritis patient’s functional disability
upon their life style. The study was carried out at the Rheumatology and outpatients clinics of ALKarama
Teaching Hospital, Baghdad Teaching Hospital AL-Kindey Teaching Hospital and Specialized
surgeries Teaching Hospital for the period of October 15th 2003 through May 13th 2004 in Baghdad
City. A purposive (non-probability) sample of (245) arthritis patients which was comprised (111)
rheumatoid arthritis patients and (134) osteoarthritis patients, was selected out of the early stated
settings. The questionnaire was comprised of

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Publication Date
Mon Aug 26 2019
Journal Name
Iraqi Journal Of Science
Study on lung infections of patients with cancer under chemotherapy

The aim of this study is to assess the prevalence of lung infections among a group of hospitalized cancer patients who received chemotherapy as well as to describe a population of these patients. The clinical data and demographic information were collected from the archived files of  in-patients  referred to  hematology center  / Baghdad Teaching Hospital / Medical City , ministry of health, Iraq  during the period  of  2018.

    This study was carried out on 250 patients with different types of cancer ,they were mostly of age group (40 - 49)  59 / 250 (23.6)% , (14-19) 49 /250 (19.6%) and (60-69) 41/ 250(16.4%) . The patients had two major types of hematological malignancies

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Publication Date
Mon May 15 2023
Journal Name
Iraqi Journal Of Science
Study of Some Serological Tests on Patients with Visceral Leishmaniasis

This study aimed to measure the alterations in serum zinc (Zn) and acute phase
proteins ( C-reactive protein and Ceruloplasmin) concentrations in patients with
visceral leishmaniasis (VL). A total of 62 individuals were enrolled in this study :
52 individuals were infected with visceral leishmaniasis and 10 individuals as
healthy control. Serum zinc levels were significantly (p<0.05) decreased in patient
group(76.25 ± 4.59 μg/dl ) when compared with healthy control (103.75 ± 3.77
μg/dl ) . C-reactive protein , as a mediator of innate immunity, removed damaged
cells by activating the classical complement pathway revealed elevated levels in
patients (4.36± 0.23mg/l ) when compared with the healthy control (2

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Publication Date
Mon Aug 30 2021
Journal Name
Al-kindy College Medical Journal
Psychosocial Impact of Childhood Cancer on Patients and their Families

Background: The presence of cancer has a profound psychological impact on the quality of life of patients and their families, on family and social relationships, and on role functioning.

Aim of the study: Assess the impact of childhood cancer on patients and their families.

Subjects and methods: A Prospective questionnaire-based study, for 151 patients, had malignancy identified by tumor registry of Children Welfare Teaching Hospital. The information was taken from the parent(s) in the presence of the patient who sometimes answered some questions during the interview.

Result: There was an interview with 151 families of children with cancer in t

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Publication Date
Sun Jan 01 2017
Journal Name
Journal Of Global Pharma Technology
Bacteriological and enzymatical study on rheumatoid arthritis patients

The current study included the collection of 175 samples (blood-urea) of patients suffering from rheumatism, collected from Baghdad Teaching Hospital (Educational Laboratory), Al-Kindy Teaching Hospital, Al-Imamian Al-Kadhimya in Medical City in Baghdad at different duration between 2016/10/1-2017/2/1. The bacterial growth results showed that 80% of urea samples positive for bacterial culture, while the rate of samples did not show any bacterial grow this 20%. The isolation subjugates to morphological, microscopically and biochemical tests, as also diagnosis by Api system. The most frequent bacterial pathogenic is E. coli which appeared highly rate (41.97)% followed by E. cloacae (21.25)%, P. aeruginosa (12.5)%, Salmonella (10)% and the pro

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