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Publication Date
Mon Jul 19 2021
Journal Name
Surgical Neurology International
Volume
12
DOI
10.25259/SNI_230_2021
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Efficacy of Gamma Knife radiosurgery in the management of pituitary prolactinoma
B.M.F.
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Background:

Gamma Knife radiosurgery (GKR) has been widely used in the management of a variety of intracranial tumors, including pituitary adenomas. Pituitary prolactinoma (Prs) is one of the most common types of these adenomas.

Methods:

This prospective study included 50 patients with pituitary Prs over a period from June 2017 to June 2018 at the Neurosciences Hospital, Baghdad/Iraq. The GKR procedure was performed using the Leksell Gamma Knife® Perfexion™, 192 beams of Cobalt 60 radiation were delivered through the intact skull to the pituitary Prs.

 Results:

There is a significant female predominance 32 (72%). The results after 6 months of GKR showed significant improvement regarding the size of adenoma, prolactin hormone level, contrast enhancement on MRI, and medical treatment.

 Conclusion:

The study showed that the GKR is a safe and effective modality of treatment in the management of pituitary Prs.
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