Objectives of this project were to study the effect of 60% crude alcoholic extract of the seeds of cyperus esculentuson induced endometritis in the mice . The plant of cyperus esculentuswas extracted by preparing Alcoholic extract 60% . One hundred microliters of saline containing Escherichia coli (104cfu) was used to induce endometritis, by a single intracervicallyinjection, and endometritis developed after 2 days from injection. The mice were divided into five groups, The first group were treated with alcoholic extract of cyperus esculentusextract 150mg/kg body weight, the second group was treated with a daily 3mg per kg body weight of gentamicin given intra peritoneal,The third group was treated by 75mg/kg of cyperus esculentusextract and 1.5mg/kg of gentamicin, The fourth group was treated by distilled water given orally by stomach tube, treatment of mice in these groups continued for 14 days while the the fifth group was (negativecontrol group). The results of the packed cell volume (P.C.V.)%, hemoglobin (Hb)g/dL of mice in alcoholic extract group(T1)after 7 days of treatment showed significant improvement as compared with mice in induction group (T4) andafter 14 days of showed no significant increase (P≤ 0.05)as compared with mice in control group (T5). While in gentamicin(T2) treated group after 7 and 14 days of treatment showed significant decrease (P≤ 0.05) as compared with mice in (T4) and (T5) , furthermore the mice in alcoholic extract and gentamicin treated group(T3) after 7 and 14 days showed significant decrease as compared with (T5) in addition showed significant increase (P≤ 0.05) as compared (T2). Total white blood cell count and all differential white blood cell of alcoholic extract group(T1)after 7 days of treatment showed significant improvement as compared with (T4) and after 14 days of treatment showed no significant increase (P≤ 0.05)as compared with (T5). While the (T2)after 7 and 14 days of treatment showed significant decrease (P≤ 0.05) as compared with (T4) and (T5) while the eosinophil percentage showed significant increase (P≤ 0.05) as compared with mice in (T5). While (T3)after 7 days showed no significant important as compared with control group, but after 14 days of treatment showed significant decrease as compared with control group, in addition showed significant increase (P≤ 0.05) as compared with mice in (T2). the results of fertility index shown in alcoholic extract treated group (T1) and alcoholic extract and gentamicin treated group (T3) was increased as compared gentamicin treated group (T2). The results of body weight and uterine weight showed significant increase (P≤ 0.05) in alcoholic extract treated group as compared with control group and mice in gentamicin group.After 7 and 14days of induction with E.coli intrauterine infection revealed presence of inflammatory cellswithin the endometrial glands and surrounding glands, glandular epithelium is degenerating and the lumen contains cellular debris) , while the groups that treated with both extract and gentamicinshowed cellular debris within the glandular endometrium. group treated with the extract for 14days noticed cellular debris within the glandular endometrium and few inflammatory cells around the endometrial glands. Thegroup treated with Gentamicin for 14days of inductionshowed also degenerating of glandular epithelium and aggregates of inflammatory cells surrounding degenerating glands and presence of hemosiderin around glands, the control group showed normal uterine tissue
Hands have consistently been an important vehicle in the transmission of disease (1). Thus, thorough hand-washing remains the single most important factor in preventing infection specially in hospitals and labs.Twenty-nine non-clinical volunteers (do not work or come in contact with a clinical or hospital setting) that lacked visible skin injuries, eczema or apparent skin disease were used, those subjects were all tested by a material of each of the three used in the study weekly and laboratory tests were done pre- and post washing.All three material were effective , Eugenol extract as effective as the bar and lotion soap. And this was confirmed statistically.Eugenol has a great antibacterial action even in small concentration and t
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Background: The beneficial gut bacterium E. coli can cause blood poisoning, diarrhoea, and other gastrointestinal and systemic disorders. Objective: This study amid to examines the antibiofilm activity of Laurus nobilis leaves extract on E. coli isolates and compares pre- and post-treatment gene expression of fimA and papC genes. Subjects and Methods: Ten isolates of E. coli were obtained from the Genetic Engineering and Biotechnology Institute, University of Baghdad, which was previously collected from Baghdad city hospitals and diagnosed by chemical tests, the diagnosis was confirmed using VITEK-2 System. The preparation of the aqueous and methanolic Laurus nobilis leaves extracts was done by using the maceration method and Soxhlet appara
... Show MoreAbstract: Background: Tribuls terrestris increases levels of various hormones in steroid family including testosterone, DEHA, and estrogen and for this reason improves sport performance, fertility in men and women, sexual function in men and women. There is, at present, lack of scientific confirmation of these supposed benefits. Therefore, this study aims to investigate the possible effect(s) of Tribuls terrestris on the mouse ovarian morphology and function, alone and in combination with other ovulation modulator agent (clomiphene citrate). Materials & Methods: A total of 49 sexually mature healthy Norway albino female mice were used in this study; 25 for pilot study and 24 for the experimental study. Experimental animals were divided
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Resin-modified glass ionomer cement tends to shrink due to polymerization of the resin component. Additionally, they are more prone to syneresis and imbibition during the setting process. This
Myelosuppression is a serious disease that is related to the malfunction of blood cells production that leads to cytopenia which is the most serious hematologic toxicity of cancer chemotherapies including cyclophosphamide, which is a strong oxazaphosphorine [a nitrogen mustard alkylating agent] that can be used alone or combined with other chemotherapeutic agents for the treatment of different malignant diseases. It induces severe bone marrow suppression by damaging hematopoietic stem cells through the generation of oxidative stress. Fisetin is a hydrophobic polyphenolic compound with a wide range of pharmacological properties such as antioxidant, anti-inflammatory, antimicrobial, osteoprotective, antidiabetic, and anti-carcinogenic activit
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Myelosuppression is a serious disease that is related to the malfunction of blood cells production that leads to cytopenia which is the most serious hematologic toxicity of cancer chemotherapies including cyclophosphamide, which is a strong oxazaphosphorine [a nitrogen mustard alkylating agent] that can be used alone or combined with other chemotherapeutic agents for the treatment of different malignant diseases. It induces severe bone marrow suppression by damaging hematopoietic stem cells through the generation of oxidative stress. Fisetin is a hydrophobic polyphenolic compound with a wide range of pharmacological properties such as antioxidant, anti-inflammatory, antimicrobial, osteoprotective, antidiabetic, and anti-carcinogenic
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Abstract: Fluoroquinolones drugs are an important class of wide
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