Chronic kidney Failure, a progressive disease, includes both medical and biochemical features that damage kidneys and decrease their abilities to work effectively, this disease is characterized by a chronic disorders to both the innate and adaptive immune systems, generate a complex and not fully understood immune dysfunction. In the present study, (30) men suffering from chronic kidney failure with age in range (40-55) year and (30) healthy men within the same range of age were enrolled in this study. The aim of this study is to highlight the role of immunological aspect (IL-35), hormonal aspects (PTH), some functional proteins and immunological electrolytes in sera of chronic kidney failure (CKF) patients. Biochemical parameters were determined in the sera of both patients and (healthy) control group. Patients enrolled in this study were newly diagnosed, they have not taken any treatment related to any chronic disease. Blood samples were collected and biochemical parameters were measured in Al- Karama teaching hospital in Baghdad (except IL-35 which was determined in the private Al-Ghazalia Laboratory) from April to November 2015. Results have reported that IL-35 level was highly significant increase in sera of chronic kidney failure patients (35.035± 0.025) pg/mL compared with healthy group (23.331±0.031) pg/mL. As well, PTH level was highly significant increased in patients group (235.032±3.841) pg/ml compared with healthy control group (49.96±0.308) pg/mL. Hemoglobin level was highly significant decreased ( 9.696±0.056) g/L in patients with control group (15.332±0.067) g/dL. Determination of IL-35, PTH, Ferritin and Other biochemical. Parameters in sera of Iraqi Men with chronic kidney failure Rasha Zuhair Jasim and Samira Muajed Yaseen 58 Vol: 13 No:2 , April 2017 DOI: http://dx.doi.org/10.24237/djps.1302.151B P-ISSN: 2222-8373 E-ISSN: 2518-9255 Also, ferritin level was highly significant decreased in chronic kidney failure patients (164.0.68±7.818) ng/mL compared with control group (313.56±1.874) ng/mL. Moreover, albumin level was highly significant decreased (3.00±0.020) g/dL in patients compared with control group (4.928±0.039)g/dL. Bicarbonate level was highly significant decreased (17.412±0.117) mmol/L in patients compared with control group (25.044±0.072) mmol/L, sodium level was non significantly increased in patients (138.65±0.288) meq/L compared with control group (135.84±0.144) meq/L, potassium level was highly significant increased in patients group (5.420±0.0186) meq/L compared with healthy control group (4.700±0.113)meq/L, calcium level was highly significant decreased in patients (7.464±0.054) mmol/L compared with control group (9.628±0.614) mmol/L, phosphate level was significantly increased in patients (4.891±0.016) mg/dL compared with control group (4.552±0.014) mg/dL. The present study concludes that IL-35 is a strong biochemical marker for Iraqi men with CKF. Moreover, this study indicated the positive relationship between (PTH, Na+ , K+ , PO4 2- ) and chronic kidney failure, and the negative relationship between (Ferritin, albumin, hemoglobin, HCO3 - ) and chronic kidney failure in Iraq.
In this paper, turbidimetric and reversed-phase ultra-fast liquid chromatography (UFLC) methods were described for the quantitative determination of ephedrine hydrochloride in pharmaceutical injections form. The first method is based on measuring the turbidimetric values for the formed yellowish white precipitate in suspension status in order to determine the ephedrine hydrochloride concentration. The suspended substance is formed as a result of the reaction of ephedrine hydrochloride with phosphomolybdic acid which was used as a reagent. The physical and chemical characteristics of the complex were investigated. The calibration graphs of ephedrine were established by turbidity method. While the second method (UFLC) was conducted using the
... Show MoreDespite the antiplaque effect of mouth-rinsing with a combination composed of miswak (Salvadora persica L.) and green tea (Camellia sinensis var. assamica) extracts, no data are available regarding its effect on gingival tissue at the molecular level. This pilot study aimed to assess the effect of oral rinsing with this combination on gingival crevicular fluid (GCF) flow and IL-1β levels. Ten subjects rinsed with either the combination, 0.12% chlorhexidine gluconate (CHX) or distilled water without toothbrushing for 4 days after receiving baseline polishing. GCF IL-1β concentration, influx, resting volume and plaque quantity were measured at baseline and after 4 days for each intervention. No significant differences in GCF flow or
... Show MoreBased on the diazotization-coupling reaction, a new, simple, and sensitive spectrophotometric method for determining of a trace amount of (BPF) is presented in this paper. Diazotized metoclopramide reagent react with bisphenol F produces an orange azo-compound with a maximum absorbance at 461 nm in alkaline solution. The experimental parameters were optimized such as type of alkaline medium, concentration of NaOH, diazotized metoclopramide amount, order additions, reaction time, temperature, and effect of organic solvents to achieve the optimal performance for the proposed method. The absorbance increased linearly with increasing bisphenol F concentration in the range of 0.5-10 μg mL-1 under ideal conditions, with a correlati
... Show MoreThis study included the determination of mercury level in twelve samples of skin whitening cream available in local market in Baghdad by atomic absorption spectrophotometer ,all the samples analyzed was contained a detectable amount of mercury. The lowest concentration of mercury in the sample C (Top Shirley) was 0.482 μg/g, and the higher concentration was 29.54 μg/g in the sample J (Norseen) .It was also noted that the samples H (whitening speckle removing day cream) and K (whitening speckle removing night cream) did not mention in the label significance the name of the country of origin and date of the validity of the product.
Hashimoto Thyroiditis (HT) is the most common autoimmune thyroid disease and the commonest cause ofhypothyroidism. C-reactive protein (CRP) is synthesized in hepatocyte in response to autoimmune disorders;strongly induced by IL-6. This study aimed to estimate serum IL-6 and CRP levels in autoimmune and non-autoimmune hypothyroidism. The present study included 60 Iraqi female hypothyroid patients divided to 30autoimmune and 30 non-autoimmune, with age ranged between 24-50 years and 30 healthy controls withage ranged between 27-52 years. Serum samples were collected from study groups. The levels of thyroidhormones (TSH, T4 and T3) were determined by using automated Chemiluminescence Immunoassay (CLIA)analysis system. Detection the levels of t
... Show MoreThe human kidney is one of the most important organs in the human body; it performs many functions
and has a great impact on the work of the rest of the organs. Among the most important possible treatments is
dialysis, which works as an external artificial kidney, and several studies have worked to enhance the
mechanism of dialysate flow and improve the permeability of its membrane. This study introduces a new
numerical model based on previous research discussing the variations in the concentrations of sodium,
potassium, and urea in the extracellular area in the blood during hemodialysis. We simulated the differential
equations related to mass transfer diffusion and we developed the model in MATLAB Simu
Fibromyalgia (FM) is a common, debilitating, and chronic pain syndrome. The women are more likely to have more tender points on examination than are their male counterparts. Iraqi study showed that FM occur in 1.5% among adolescents of Iraqi population. In compare to normal healthy women, present study was revealed that Iraqi women with FM have significant elevation of calcium (p = 0.003) with significant reduction of magnesium (p = 0.001), whereas the inorganic phosphorous was not differs (p = 0.31). In conclusion, magnesium and calcium would play a crucial role in etiopathogenesis of fibromyalgia.
Key words: calcium, magnesium, phosphorous, Fibromyalgia.
Acute myeloid leukemia is a malignant disease results from mutation in a multipotent haemopoietic stemcell. The study aimed to investigate NPM1 and FLT3-ITD mutations in Iraqi patients with AML and correlateresults with other clinical and laboratory findings. Fifty-eight AML patients, admitted to Baghdad TeachingHospital from October 2019 till March 2020 in addition to 25 normal controls, were included in the study.A detailed history, laboratory investigations including FLT3-ITD and NPM1 mutations were collected fromand analyzed. FLT3-ITD was detected in 17.24% of patients, NPM1 mutation in 10.34%. Most of thepatients are presented with pallor. FLT3-ITD mutation had a higher blast cell count (74%) while NPM1mutation had higher WBCs
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