Chronic kidney Failure, a progressive disease, includes both medical and biochemical features that damage kidneys and decrease their abilities to work effectively, this disease is characterized by a chronic disorders to both the innate and adaptive immune systems, generate a complex and not fully understood immune dysfunction. In the present study, (30) men suffering from chronic kidney failure with age in range (40-55) year and (30) healthy men within the same range of age were enrolled in this study. The aim of this study is to highlight the role of immunological aspect (IL-35), hormonal aspects (PTH), some functional proteins and immunological electrolytes in sera of chronic kidney failure (CKF) patients. Biochemical parameters were determined in the sera of both patients and (healthy) control group. Patients enrolled in this study were newly diagnosed, they have not taken any treatment related to any chronic disease. Blood samples were collected and biochemical parameters were measured in Al- Karama teaching hospital in Baghdad (except IL-35 which was determined in the private Al-Ghazalia Laboratory) from April to November 2015. Results have reported that IL-35 level was highly significant increase in sera of chronic kidney failure patients (35.035± 0.025) pg/mL compared with healthy group (23.331±0.031) pg/mL. As well, PTH level was highly significant increased in patients group (235.032±3.841) pg/ml compared with healthy control group (49.96±0.308) pg/mL. Hemoglobin level was highly significant decreased ( 9.696±0.056) g/L in patients with control group (15.332±0.067) g/dL. Determination of IL-35, PTH, Ferritin and Other biochemical. Parameters in sera of Iraqi Men with chronic kidney failure Rasha Zuhair Jasim and Samira Muajed Yaseen 58 Vol: 13 No:2 , April 2017 DOI: http://dx.doi.org/10.24237/djps.1302.151B P-ISSN: 2222-8373 E-ISSN: 2518-9255 Also, ferritin level was highly significant decreased in chronic kidney failure patients (164.0.68±7.818) ng/mL compared with control group (313.56±1.874) ng/mL. Moreover, albumin level was highly significant decreased (3.00±0.020) g/dL in patients compared with control group (4.928±0.039)g/dL. Bicarbonate level was highly significant decreased (17.412±0.117) mmol/L in patients compared with control group (25.044±0.072) mmol/L, sodium level was non significantly increased in patients (138.65±0.288) meq/L compared with control group (135.84±0.144) meq/L, potassium level was highly significant increased in patients group (5.420±0.0186) meq/L compared with healthy control group (4.700±0.113)meq/L, calcium level was highly significant decreased in patients (7.464±0.054) mmol/L compared with control group (9.628±0.614) mmol/L, phosphate level was significantly increased in patients (4.891±0.016) mg/dL compared with control group (4.552±0.014) mg/dL. The present study concludes that IL-35 is a strong biochemical marker for Iraqi men with CKF. Moreover, this study indicated the positive relationship between (PTH, Na+ , K+ , PO4 2- ) and chronic kidney failure, and the negative relationship between (Ferritin, albumin, hemoglobin, HCO3 - ) and chronic kidney failure in Iraq.
Topological indices provide important insights into the structural characteristics of molecular graphs. The present investigation proposes and explores a creative graph on a finite group G, which is known as the RIG. This graph is designated as ΓRS G2(4) indicating a simple undirected graph containing elements of G. Two distinct ertices are regarded as nearly the same if and only if their sum yields a non-trivial involution element in G. RIGs have been discovered in various finite groups. We examine several facets of the RIG by altering the graph through the conjugacy classes of G. Furthermore, we investigate the topological indices as applications in graph theory applying the distance matrix of the G2(4) group.
The possible effects of COVID-19 vaccines on reproductive health and male fertility in particular have been discussed intensely by the scientific community and the public since their introduction during the pandemic. On news outlets and social media platforms, many claims have been raised regarding the deleterious effects of COVID-19 vaccines on sperm quality without scientific evidence. In response to this emerging conflict, we designed this study to evaluate and assess the effect of the Pfizer-BioNTech mRNA COVID-19 vaccine on male fertility represented by the semen analysis parameters.
In this work, we studied the effect of power variation on inductively coupled plasma parameters using numerical simulation. Different values were used for input power (750 W-1500 W), gas temperature 300K, gas pressure (0.02torr), 5 tourns of the copper coil and the plasma was produced at radio frequency (RF) 13.56 MHZ on the coil above the quartz chamber. For the previous purpose, a computer simulation in two dimensions axisymmetric, based on finite element method, was implemented for argon plasma. Based on the results we were able to obtain plasma with a higher density, which was represented by obtaining the plasma parameters (electron density, electric potential, total power, number density of argon ions, el
... Show MoreA method is developed for the determination of iron (III) in pharmaceutical preparations by coupling cloud point extraction (CPE) and UV-Vis spectrophotometry. The method is based on the reaction of Fe(III) with excess drug ciprofloxacin (CIPRO) in dilute H2SO4, forming a hydrophobic Fe(III)- CIPRO complex which can be extracted into a non-ionic surfactant Triton X-114, and iron ions are determined spectrophotometrically at absorption maximum of 437 nm. Several variables which impact on the extraction and determination of Fe (III) are optimized in order to maximize the extraction efficiency and improve the sensitivity of the method. The interferences study is also considered to check the accuracy of the procedure. The results hav
... Show MoreA chemometric method, partial least squares regression (PLS) was applied for the simultaneous determination of piroxicam (PIR), naproxen (NAP), diclofenac sodium (DIC), and mefenamic acid (MEF) in synthetic mixtures and commercial formulations. The proposed method is based on the use of spectrophotometric data coupled with PLS multivariate calibration. The Spectra of drugs were recorded at concentrations in the linear range of 1.0 - 10 μg mL-1 for NAP and from 1.0 - 20 μg mL-1 for PIR, DIC, and MEF. 34 sets of mixtures were used for calibration and 10 sets of mixtures were used for validation in the wavelength range of 200 to 400 nm with the wavelength interval λ = 1 nm in methanol. This method has been used successfully to quant
... Show MoreA simple, accurate, and cost-efficient UV-Visible spectrophotometric method has been developed for the determination of naphazoline nitrate (NPZ) in pure and pharmaceutical formulations. The suggested method was based on the nucleophilic substitution reaction of NPZ with 1,2-naphthoquinone-4-sulfonate sodium salt in alkaline medium at 80°C to form an orange/red-colored product of maximum absorption (λmax) at 483 nm. The stoichiometry of the reaction was determined via Job's method and limiting logarithmic method, and the mechanism of the reaction was postulated. Under the optimal conditions of the reaction, Beerʼs law was obeyed within the concentration range 0.5–50 μg/mL, the molar absorptivity value (ε) was 5766.5 L × mol–1 × c
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