BACKGROUND: COVID-19 is resulted from severe acute respiratory syndrome coronavirus 2, which initiated in China in December 2019. Parasites are efficient immune modulators because their ability to stimulate an immune response in infected persons. AIM: This study aims to detect if there is a probable relationship between intestinal parasitic infections and COVID-19. METHODS: Ninety patients consulted at Al-Kindy Teaching Hospital (Al-Shifa center) from October 2020 till April 2021, confirmed infection with COVID-19 by PCR. Stool examination was done for detecting intestinal parasites. RESULTS: From 90 patients, males were 63 (70%), with median age 32 years, while females were 27 (30%), with age 24–44 years. Asymptomatic patients were 8.1 (9%), patients with moderate symptoms 22.5 (25%) cases, while the rest were 59.4 (66%) cases who required enter to the intensive care unit, with symptoms including cough (80%), dyspnea (74%), fever (56%), headache (43%), chest pain (37%), sore throat (35%), myalgia (32%), diarrhea (27%), and hemoptysis (3%). CONCLUSION: There is inverse relationship between parasitic infection and COVID-19 infections, and it is significant to understand the action between parasites and microbiome, also its function in COVID-19 pathogenicity.
