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Assessment <b></b>of Serum P53 Protein Level in Adult Patients with Acute Myeloid Leukemia in Correlation with Response to Treatment

Background: Acute myeloid leukemia (AML) is an adult leukemia characterized by rapid proliferation of undifferentiated myeloid precursors, leading to bone marrow (BM) failure and impaired erythropoiesis. The p53 tumor suppressor protein regulates cell division and inhibits tumor development by preventing cell proliferation of altered or damaged DNA. It orchestrates various cellular reactions, including cell cycle arrest, DNA repair, and antioxidant properties. Objectives: To investigate the relationship of P53 serum level with hematological findings, remission, and survival status in de novo AML patients. Methods: This is a cross-sectional study that enrolled 63 newly diagnosed de novo AML patients, and 15 sex- and age-matched healthy persons as a control group. Serum P53 levels were assessed using the enzyme-linked immunosorbent assay (ELISA) technique before initiating induction chemotherapy. The study was performed between November 2022 and May 2023 at the Hematology and Bone Marrow Transplant Center of the Medical City Complex in Baghdad. Results: There were significantly lower P53 serum levels in AML patients before starting chemotherapy compared to the control group. However, no substantial difference in P53 levels was identified between AML patients achieving complete remission and those exhibiting no response, nor between alive and deceased individuals. Furthermore, there was a positive yet statistically non-significant correlation between serum P53 levels and age, and no significant relationship between P53 levels and sex or various hematological parameters. Conclusion: P53 levels are low in AML patients. They are not associated with remission status or survival after six months and are not correlated with hematological values.

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Publication Date
Wed Dec 14 2016
Journal Name
Journal Of Baghdad College Of Dentistry
Immunohistochemical Expression of Endocan in Ameloblastoma

Background: Ameloblastoma is the most common clinically significant odontogenic tumor, known for its locally invasive potential and frequent recurrences unless treated radically. Endocan is a soluble proteoglycan which is reported to have prognostic implications in multiple human diseases and tumors. This study aims to describe the expression of endocan in ameloblastoma. Materials and methods: With immunoperoxidase method; tissue sections of formalin fixed- paraffin embedded blocks for ameloblastomas were stained with monoclonal antibodies to endocan, the localization of the endocan expression was examined and the resulting scores of the tissue sections were analyzed according to age, sex, site and tumor subtype. Results: endocan was found

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Publication Date
Wed Jan 01 2014
Journal Name
Journal Of The College Of Languages (jcl)
The Use of Idioms in Advertisements

The power of advertising is immense. Producers of commercial goods and services routinely pour vast sums into promoting their wares through the advertising media, knowing  that a successful campaign can win them vital market share , and that failure to advertise effectively can have devastating results . The function of advertising is promotional ; to draw our  attention. In order  to achieve this function it must reach its target  audience , then capture that audience with a message that is both attractive and memorable.

         From a linguistic point of view, the language of advertising must be informative, instructive , distinctive and persuasive . It must employ&nb

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Publication Date
Fri Mar 17 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Complex of Lascoux in Partition (3,3,2)

In this paper, the complex of Lascoux in the case of partition (3,3,2) has been studied by using diagrams ,divided power of the place polarization ) (k ij ,Capelli identites and the idea of mapping Cone .

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Publication Date
Thu Aug 03 2023
Journal Name
Hind
Diversity of Freshwater Fishes in Iraq

Many studies have focused on identifying and classifying freshwater fishes in Iraq, concerned with describing, organizing, and drawing up a list of freshwater fishes in Iraq or the Tigris and Euphrates rivers. Within the most recent updates at the beginning of 2023, 53 native freshwater and 20 exotic (alien or introduced) fish species are recorded and described. This study reviewed the database of morphology and molecular studies of freshwater fish in Iraq and reported species while surveying the fish fauna at different water bodies of the country from 2010 to the beginning of 2023. In conclusion, 29 species (about 40.3%) of all 72 fish species in Iraq still need to be available information on their molecular data.

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Publication Date
Wed Jan 04 2023
Journal Name
College Of Islamic Sciences
Regulations of changes in Sharia policy

Regulations of changes in Sharia policy

Variables include jurisprudential rulings that may be subject to change, alteration and interpretation, depending on the mujtahid’s view of the ruling, or changing it and switching to another view, and the variables are the crucial issues that befell the nation of Islam. It was not neglected by Islamic legislation, but rather the setting of controls that took into account in every incident the norms, interests and purposes.

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Publication Date
Sun Sep 02 2012
Journal Name
Baghdad Science Journal
Occurrence of Pneumococcal Meningitis in Iraq

This study focuses on the relative frequency of Streptococcus pneumoniae in children with culture-proven bacterial meningitis. The epidemiology has been investigated with clinical and laboratory findings in The Central Public Health Laboratory, Iraq from April to September, 2010. From (138) samples , (55) cases (39.85 %) were diagnosed by physician as bacterial meningitis, (23) cases (16.66 %) as viral menginitis , (18) cases (13.04 %) as different medical cases (e.g febrile convulsion , meningoencephalitis , epilepsy …etc) and (42) cases (30.43 %) as unidentified medical cases. For bacterial meningitis S.pneumoniae was isolated from (10) cases (18.18 %) only. The median age for bacterial meningitis was (130.75) month and the predomina

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Publication Date
Sun May 12 2019
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Prevalence of Fibromyalgia in Infertile Women

Background: Fibromyalgia is a functional disorder of growing importance characterized by chronic widespread musculoskeletal pain. It frequently affects women of child bearing age. Infertility is failure to achieve pregnancy within a 12 month period for sexually active individuals under 35 years of age and failure to conceive within a 6 months period for those over 35 years, which can have a major psychosocial impact on the affected person’s life.

Objectives: To estimate the prevalence of fibromyalgia among a sample of infertile women; and to study its relationship with age, length of marriage, duration and type of infertility.

Patients and Methods: A cross-sectional stu

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Publication Date
Sun Apr 24 2022
Journal Name
Journal Of The Faculty Of Medicine Baghdad
use of dietary supplement in Iraq

Background: Dietary supplementation is a common strategy to achieve a specific health status or performance benefit. The aim of this study was to describe the use of dietary supplement in Iraqi genders.

Patients and Methods:  several questions on dietary supplement use were asked as a part of single performed on 112 female and 247 women aged 35–74 years in 2021 .n = 359) ,reported the frequency and prevalence of supplement use by sex and type of supplement .

Results: the mean percentage of dietary supplement use varied among female and men. Use was higher in women than in men. Vitamins, minerals were the predominant types of supplements reported, but the

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Publication Date
Sun Apr 01 2007
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Causes of Vomiting in Hospitalized Children

Background: vomiting is a very common symptom of disease in childhood, it occurs both in gastrointestinal and non-gastrointestinal diseases.
Objectives: Our aim of the study was to find out the causes of vomiting in different age group, the improper management of vomiting in daily practice and to emphasis on the usefulness of imaging study in the diagnosis.
Methods: A prospective study was carried out on patients presented with vomiting admitted to Children Welfare Teaching Hospital from the first of Dec. 2001 to the end of April 2002 .The age ranged between early neonatal periods to 12 years of age.
Reults: A total of 100 child were included in this study,(65) male (35) female male to female ratio 

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Publication Date
Tue Dec 24 2019
Journal Name
Journal Of Legal Sciences
Interest in the criminalzation of smoking

Smoking is one of the biggest pests in societies and is one of the main threats to human health as the problem goes beyond the smoker and the non smoker around it and is transmitted through the air and produces what is known as passive smoking.

Scientific studies and medical research confirm that at least 90% of patients with oral, pharyngeal, laryngeal, and other cancers are among smokers. It is known that the risk of these cancers among smokers increases as the amount of smoking increases. That the incidence of these malignant tumors among smokers rises between 6 to 10 times the incidence in non-smokers, Recent scientific research has proved beyond doubt that tobacco contains precursors, active carcinogens, activated cancer cel

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