HLA genes are associated with more than 100 diseases, including infectious diseases like HIV, and some cancers. Some autoimmune conditions, including diabetes and multiple sclerosis, are also linked to specific variations in the HLA. In MS, the immune system fails to distinguish between the body's tissues and foreign proteins resulting in it attacking myelin as if it were foreign. Several HLA genes have been found to influence the risk of developing MS. Some variants make an individual more likely to develop MS, whereas others may have a protective effect and decrease the risk. Although the precise genes involved in the development of multiple sclerosis are still not fully understood, research has identified one HLA gene that is more prevalent in women with MS and may be part of the explanation why more women than men get the condition.
The Relation between Human Leukocyte Antigen and Multiple Sclerosis
HLA
Multiple sclerosis
disease susceptibility
genetic factor.
Publication Date
Sat Oct 01 2016
Journal Name
Journal Of Theoretical And Applied Information Technology
Factors affecting global virtual teams’ performance in software projects
Today the trend is to perform software development work via distributed geographical area among team
individual or even as an organization. However
due to the global market and international presence of many companies
there is a need to implement a global virtual teams. The global virtual team members are gradually engaged in globalized business environments across space
time and organizational boundaries via information and communication technologies. A global virtual team relies on communication
collaboration
and information exchange are the most important criteria in global virtual teams’ operations. The purpose of this paper is to answer two research questions. The first research question is to identify the factors affecting global virtual teams’ performance. A systematic literature review was conducted to answer the first research question. The second research question is on what the rank of the factor affecting the global virtual teams’ performance according to their level of effect on global virtual teams’ performance. Online survey was conducted within 103 developers and IT managers from eight IT companies to answer the second research question. The Statistical Package for Social Science (SPSS 22) was used to analyze the collected data. In this study
we investigated factors that affect global virtual teams’ performance
factors considered include cultural differences
language problems
time-zone differences
team size
technical problems
lack of trust
lack of sufficient training
and ICT problems. Also the findings indicated that lack of sufficient training is the highest level of effect on global virtual teams’ performance. On the other hand
team size is the lowest level of effect on global virtual teams’ performance. © 2005 - 2016 JATIT & LLS. All rights reserved.
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