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Study on the anti-microbial effect of Sinigrin against some pathogenic bacterial species

The increasing anti-bacterial drug resistance is one of the biggest challenges facing doctors around the globe, so finding alternative treatments is one of the ideal options to overcome this problem. The cruciferous family is one of the wealthiest plants worldwide because it contains the most important secondary metabolites, glucosinolates, known for their anti-microbial properties. The present study aimed to evaluate the anti-bacterial effect of glucosinolates (Sinigrin) against eight bacterial isolates (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Actinomyces, Proteus mirabilis and Streptococcus pneumoniae). The current study investigated six concentrations of pure Sinigrin (100, 300, 500, 700, 900, and 1100 µg/ml). The sensitivity of bacterial isolates to various antibiotics was tested by VITIK 2DensiCheck equipment. The anti-bacterial activity of Sinigrin was assessed using the agar diffusion method, and the microtiter plate method measured the minimal inhibitory concentration (MIC). The highest anti-bacterial effect of Sinigrin was observed against S. aureus, E. coli, and E. faecalis. The anti-bacterial activity started as lower as 100 µg/ml, while a moderate effect was seen against P. aeruginosa and K. pneumoniae at a concentration lower than 700 µg/ml. On the other hand, Sinigrin was not effective against Actinomyces, P. mirabilis, and S. pneumoniae. It can be concluded from the present study that Sinigrin has an anti-bacterial effect on some isolates of bacteria which suggests the possibility of using Sinigrin as alternative medicine in the future. Keywords: Anti-bacterial activity, Agar well diffusion, Glucosinolates, Minimum inhibition concentration and antibiotic susceptibility, Sinigrin.

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Publication Date
Thu Nov 01 2018
Journal Name
Iraqi National Journal Of Nursing Specialties
Testing Bromocriptine Dose Necessary For Suppression of Lactation in Rats: Morphological Study

Abstract: Objectives: The lowest dose of bromocriptine, necessary for suppression of lactation in rats, was estimated in this investigation. Methodology: Fifty healthy lactating rats were treated with different doses of bromocriptine. Cessation of lactation was assessed clinically and histologically. Results: Revealed that the lowest dose capable of lactation suppression is 4 mg bromocriptine / kg body wt. / day. It is very important to know the exact dose, which can suppress lactation in rats because these laboratory animals are commonly employed in experiments concerning this topic. Key words: Bromoci

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Publication Date
Sat Mar 18 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Preparation of Silver Nanoparticles by Sol - Gel Method and Study their Characteristics

 Powder of silver nanoparticles was prepared by Sol - Gel method successfully using silver nitrate , (AgNO3) gesture is added to sodium citrate (C6H5O7Na3) as a reducing agent and by using  Magnetic Stirrer to mix the solutions and heated then using centrifuge machine to separate the silver nanoparticles from solution .It is then dried in an oven at a temperature 40oC for 24 hours.     Structure characteristics was studied , the synthetic silver powder was prepared through the use of an (XRD). Results showed the composition of silver nanoparticles is a (fcc) and a constant lattice (4.086 ± 0.006 Ã…) by comparing it with standard tables (JCPDS) which is found perfectly matched to file with a number 04-0783, which

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Publication Date
Fri Jul 01 2022
Journal Name
Iraqi Journal Of Science
Study of Actual Jupiter Observation Days at UFRO Station During 2004 Year

In this Paper, There are attempts to compare the actual Observation Days in Decametric range (18-28 MHz), For Jupiter received by UFRO Earths’ station with the Prediction Observation Days that the Jupiter can be observed at Jupiter’s suitable location. The Jupiter’s Radio Observations actual data during year 2004, was taken from (Radio JOVE Data Archive website). The determination of the prediction days carried out by using the (Radio-Jupiter pro Jove Edition) software for Jupiter radio storms at UFRO station coordinates. Some Cases are considered according to Jupiter’s altitudes and Sun location at UFRO station Sky. The conclusion is, it could be found that there are (82) number of Predictions Observation Days, and It’s found

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Publication Date
Tue Nov 19 2024
Journal Name
Journal Of Baghdad College Of Dentistry
An in-vitro scan electron microscope comparative study of dentine-Biodentine interface

Background: Restoration of the gingival margin of Class II cavities with composite resin continues to be problematic, especially where no enamel exists for bonding to the gingival margin. The aim of study is to evaluate the marginal leakage at enamel and cementum margin of class II MOD cavities using amalgam restoration and modern composite restorations Filtek™ P90, Filtek™ Z250 XT (Nano Hybrid Universal Restorative) and SDR bulk fill with different restoratives techniques. Materials and method: Eighty sound maxillary first premolar teeth were collected and divided into two main groups, enamel group and cementum group (40 teeth) for each group. The enamel group was prepared with standardized Class II MOD cavity with gingival margin (1 m

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Publication Date
Sun Sep 30 2007
Journal Name
Iraqi Journal Of Chemical And Petroleum Engineering
Study of Catalysts Deactivation in Isomerization Process to Produce High Octane Gasoline

In this study  the isomerization of desulfuerized light Iraqi petroleum naphtha (Al-Dura Refinery) with boiling point range of 37 to 124 °C , 80.5 API specific gravity and 68.2 octane number has been investigated. Two types of catalysts were prepared (Pt/HX and Pt/SrX) by impregnation of 0.8 wt% Pt on l 3X-zeolite. The catalyst activity and selectivity toward isomerization, and catalyst deactivation were investigated.

The isomerization unit consisted of a vertical tubular stainless steel reactor of 2 cm internal diameter, 3 cm external diameter and 68 cm height. The operating pressure was atmospheric for all experimental runs.  The liquid flow of light­naphtha was 0.4 Uh, and the catalyst weight was 50 gm, H/

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Publication Date
Thu Mar 30 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Spectroscopic Study for Determination of Amoxicillin Using Cobalt(II) as Complexing Metal

         This study includes analytical methods for the determination of the drug amoxicillin trihydrate (Amox.) in some pharmaceutical preparations using Cobalt ion (Co(II)) as complexing metal. The best conditions for complexation were: the reaction time was 20 minutes, pH=1.5 and the best temperature of reaction was 70 ËšC. Benzyl alcohol was the best solvent for extraction the complex.

Keywords: Amoxicillin, Cobalt(II), Complex, Molar ratio.

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Publication Date
Sun Dec 04 2011
Journal Name
Baghdad Science Journal
Clinico – Hemato and Biochemical Study of Anemia in Cachectic Cattle in Baghdad

The study was carried out in order to evaluate clinically and laboratory cachectic animals suffering from anemia. Animal examined were 50 cow and calf. The study include clinical, hemato and biochemical test for accurate diagnosis of cachexia in cows and calves . Blood smears were conducted for detection of blood parasites , fecal examination for gastrointestinal parasites and Different parameters were applied for classification of cachexia , depending on bony projection specially ribs and pelvic and generalized muscular atrophy. However , The study revealed an incidence of cachexia and anemia of blood parasites was including Theileria, Anaplasma, gastrointestinal parasites, ten cases were shown foreign body syndrome while other tens wer

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Publication Date
Fri Apr 01 2016
Journal Name
Journal Of Engineering
Numerical Study of Heat Transfer Enhancement in Heat Exchanger Using AL2O3 Nanofluids

In this study, the flow and heat transfer characteristics of Al2O3-water nanofluids for a range of the Reynolds number of 3000, 4500, 6000 and 7500 with a range of volume concentration of 1%, 2%, 3% and 4% are studied numerically. The test rig consists of cold liquid loop, hot liquid loop and the test section which is counter flow double pipe heat exchanger with 1m length. The inner tube is made of smooth copper with diameter of 15mm. The outer tube is made of smooth copper with diameter of 50mm. The hot liquid flows through the outer tube and the cold liquid (or nanofluid) flow through the inner tube. The boundary condition of this study is thermally insulated the outer wall with uniform velocity a

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Publication Date
Fri Dec 01 2023
Journal Name
Al-khwarizmi Engineering Journal
Working Memory Classification Enhancement of EEG Activity in Dementia: A Comparative Study

The purpose of the current investigation is to distinguish between working memory ( ) in five patients with vascular dementia ( ), fifteen post-stroke patients with mild cognitive impairment ( ), and fifteen healthy control individuals ( ) based on background electroencephalography (EEG) activity. The elimination of EEG artifacts using wavelet (WT) pre-processing denoising is demonstrated in this study. In the current study, spectral entropy ( ), permutation entropy ( ), and approximation entropy ( ) were all explored. To improve the  classification using the k-nearest neighbors ( NN) classifier scheme, a comparative study of using fuzzy neighbourhood preserving analysis with -decomposition ( ) as a dimensionality reduction technique an

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Publication Date
Sun Apr 16 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Structure,Rietveld Refinement Study of BaCoxTixFe12-2xO19 ferrite Using Powder XRD Analysis

    BaCoxTixFe12-2xO19 (x=0.1, 0.5, 0.7, 0.9, 1.7) were prepared using powder technology technique . X-ray diffraction with diffractometer CuKα radiation analysis and Rietveld refinement of the samples were studied and showed a single phase of hexagonal structure with SP63/mmc space group . Lattice parameters, cell volume , crystallite size and x-ray density were determined .The hexagonal structure was represented by using PowderCell program showing the atomic positions of Co ,Ti, and Fe ions.
 

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