Braces in straight bridge systems improve the lateral-torsional buckling resistance of the girders by reducing the unbraced length, while in horizontally curved and skew bridges, the braces are primary structural elements for controlling deformations by engaging adjacent girders to act as a system to resist the potentially large forces and torques caused by the curved or skewed geometry of the bridge. The cross-frames are usually designed as torsional braces, which increase the overall strength and stiffness of the individual girders by creating a girder system that translates and rotates as a unit along the bracing lines. However, when they transmit the truck’s live load forces, they can produce fatigue cracks at their connections to the girders. This paper investigates the effect of using different details of cross-frames to girder connections and their impacts on girder stresses and twists. Field testing data of skewed steel girders bridge under various load passes of a weighed load vehicle incorporated with a validated 3D full-scale finite element model are presented in this study. Two types of connections are investigated, bent plate and pipe stiffener. The two connection responses are then compared to determine their impact on controlling the twist of girder cross-sections adjacent to cross-frames and also to mitigate the stresses induced due to live loads. The results show that the use of a pipe stiffener can reduce the twist of the girder’s cross-section adjacent to the cross-frames up to 22% in some locations. In terms of stress ranges, the pipe stiffener tends to reduce the stress range by 6% and 4% for the cross-frames located in the abutment and pier skew support regions respectively.
Background: Acute myeloid leukemia (AML) is an adult leukemia characterized by rapid proliferation of undifferentiated myeloid precursors, leading to bone marrow (BM) failure and impaired erythropoiesis. The p53 tumor suppressor protein regulates cell division and inhibits tumor development by preventing cell proliferation of altered or damaged DNA. It orchestrates various cellular reactions, including cell cycle arrest, DNA repair, and antioxidant properties. Objectives: To investigate the relationship of P53 serum level with hematological findings, remission, and survival status in de novo AML patients. Methods: This is a cross-sectional study that enrolled 63 newly diagnosed de novo AML patients, and 15 sex- and age-matched healt
... Show MoreRespiratory syncytial virus (RSV) is an important cause of respiratory infection among children and infants globally. The first line of the immune response against this virus is neutrophils, macrophages, and innate lymphoid cells. Antigen‑presenting cells such as dendritic cells which present the viral antigen to T lymphocytes that mediate viral clearance by T cytotoxic cells and initiate systemic lymphopenia. Humoral immunity will also be stimulated through B‑cell‑stimulating factors derived from epithelial cells of the respiratory tract that play an important factor in antibody production and induction memory to reinfection through IgG and IgA protective antibodies that are useful in vaccine production.
Alternative distribution to estimate the Dose – Response model in bioassay excrement
This research concern to study five different distribution (Probit , Logistic, Arc sine , extreme value , One hit ), to estimate dose –response model by using m.l.e and probit method This is done by determining different weights in each distribution in addition find all particular statistics for vital model .
The current study introduces a novel technique to handle electrochemical localized corrosion in certain limited regions rather than applying comprehensive cathodic protection (CP) treatment. An impressed current cathodic protection cell (ICCPC) was fabricated and firmly installed on the middle of a steel structure surface to deter localized corrosion in fixed or mobile steel structures. The designed ICCPC comprises three essential parts: an anode, a cathode, and an artificial electrolyte. The latter was developed to mimic the function of the natural electrolyte in CP. A proportional-integrated-derivative (PID) controller was designed to stabilize this potential below the ICCPC at a cathodic potential of −850 mV, which is crucial for prote
... Show MoreThe purpose of this study is designate quenching and tempering heat treatment by using Taguchi technique to determine optimal factors of heat treatment (austenitizing temperature, percentage of nanoparticles, type of base media, nanoparticles type and soaking time) for increasing hardness, wear rate and impact energy properties of 420 martensitic stainless steel. An (L18) orthogonal array was chosen for the design of experiment. The optimum process parameters were determined by using signal-to-noise ratio (larger is better) criterion for hardness and impact energy while (Smaller is better) criterion was for the wear rate. The importance levels of process parameters that effect on hardness, wear rate and impact energy propertie
... Show MoreThe aim of this study was to evaluate tensile properties of low and medium carbon ferrite -martensite dual phase steel, and the effect cryogenic treatment at liquid nitrogen temperature (-196 ºC) on its properties. Low carbon steel (C12D) and medium carbon steels (C32D & C42D) were used in this work. For each steel grade, five groups of specimens were prepared according to the type of heat treatment. The first group was normalized, the second group was normalized and subsequently subjected to cryogenic treatment then tempered at (200 ºC) for one hour, the third group was quenched from intercritical annealing temperature of (760 ºC) to obtain dual phase (DP) steel, the fourth and fifth groups were both quenched from (760 ºC), but
... Show MoreThis research is an attempt to unveil the cover and unveil a matter that has become mysterious to those who came after Sibweh of the grammar scholars; It took place as a result of the work of the scribes.
This study focused on determining the markers of Macrophage migration inhibitor (MIF), as well as the N-telopeptides of type I bone collagen (NTX), and some other parameters (alkaline phosphatase (ALP), vitamin D (Vit D), calcium (Ca), phosphorus (P), and magnesium (Mg), and their correlation with other parameters in osteoporosis. One hundred ten subjects were involved in the current study. There were two groups of patients: group I (30) women with severe osteoporosis and group II (30) women with mild osteoporosis. For comparison, 50 apparently healthy individuals were included as a control. Serum levels of MIF, and NTX were significantly higher in groups I and II as compared to the control group, which indicate that these two parameters
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