Type 1 diabetes (T1D) is an autoimmune disease with chronic nature resulting from a combination of both factors genetic and environmental. The genetic contributors of T1D among Iraqis are unexplored enough. The study aimed to shed a light on the contribution between genetic variation of interleukin2 (IL2) gene to T1D as a risk influencer in a sample of Iraqi patients. The association between IL2−330 polymorphism (rs2069762) was investigated in 322 Iraqis (78 T1D patients and 244 volunteers as controls). Genotyping for the haplotypes using polymerase chain reaction test – specific sequence primer (PCR-SSP) for (GG, GT, and TT) genotypes corresponding to (G and T) alleles were performed. A significant association revealed a decreased freq

Baghdad:

Background : It is quite accepted that interleukins (IL) in general play a crucial role in response to injuy , infection and on cogenic trans formation , among there are IL-6 and ILJO.
Aim of this study is to find out the possible role of IL_ and IL, 10 in colo rectaI carcima in Iraqi patients.
Subjects and Methods: forty patients with colorectal cancer (CRC) composed with 30 healthy controls were enrolled in this study. Serum conc. Of IL-6 and IL -lOwere estimated in both groups using ELIZA technique.
Results: Serem levels of IL-6 and IL-10 were significantly increased (P<0.001) in compassion with control group.
Conclusion: these cytokins could be used as a markers for tumor progression .

Summary:
Background: The incidence of cancer of the cervix is comparatively low in Iraq, as in most other Islamic countries. Pre invasive lesions of the uterine cervix can be detected by Pap smears in their preclinical course, a fact which documents the significant role of cervical cytology in gynecological practice.
Objective: To emphasize the role of cervical cytopathology (Pap smears) in the detection and follow up of various cervical lesions that may predispose to cervical carcinoma with special emphasis on Cervical Intraepithelial Neoplastic (CIN) conditions or dysplasias.
Patients and Methods: This retrospective study M’as performed on 1500 women aged 20 years and above who attended the private clinical laboratory of th

Background: Multiple Sclerosis disease is a demyelination process which interferes with the neuronal signal transmission, thus leading to different cognitive and physical dysfunctions like optic neuritis, motor, sensory and coordination problems. Recently many researches have been directed toward studying the relation between some genes and multiple sclerosis. Among the important genes to be studied in multiple sclerosis is the forkhead box P3 gene expression.
Objectives: The aims of the present work were to study the expression of forkhead box P3 gene by real time polymerase chain reaction, and to perform chromosomal analysis on the multiple sclerosis patients peripheral blood lymphocytes.
Patients and methods: A case-control stud

Cholesteryl ester transfer protein gene contains some single nucleotide polymorphisms, which have been associated with serum high-density lipoprotein concentration and other lipoproteins. This study is done for determining of cholesteryl ester transfer protein polymorphism and evaluate its effect on serum lipid profile concentrations in some hyperlipidemic patients compared with healthy subjects in Salah Al-din governorate-Iraq. Blood samples were taken from (90) patients suffering from hyperlipidemia, and (70) samples that were apparently healthy controls.  Serum lipid concentrations were measured by enzymatic assays. The polymorphism was genotyped using polymerase chain reaction restriction fragment length polymorphism analysis.&n

Background: Temperatures and seasons have been suggested as environmental factors that influence fecundity in mammals. It has been reported that there is a link between human fertility and seasonal changes.

Objectives: The aim of the study was to assess whether the seassonal changes in tempreture, humidity, light intensity and light duration do influence fecundity and reproduction in the study group of Iraqi women who were from Baghdad.

Patients and Methods:This study was conducted on 1638 randomly selected womenn who were from Baghdad city and were normaly delivered at Al- Elwiyah Maternity Teaching Hospital during 2014. A detailed questionnaire form was filled through d

This study aimed to compare lysyl oxidase-1 level in diabetic patients with and without renal dysfunction, that LOX-1 may be an indicator for the early stage of diabetic nephropathy (DN). In addition to finding it is a relationship with kidney functions in Iraqi diabetic patients with and without renal dysfunction. Blood was obtained from 25 healthy individuals as a control group (G1), 25 diabetic patients with renal dysfunction, and 25 diabetic patients without renal dysfunction. Age range 40-60 years for all subjects. BMI (25-27) Kg/m2 . The serum was used for the analysis of LOX-1, FBG, urea, creatinine and uric acid. Whole blood is used for the determination of HbA1C. Results of FBG and HbA1C revealed a significant increase in G2 and G

Background: - This study was carried out to investigate the ability of Streptococcus bovis to colonise colorectal cancer.
Patients and Methods: - A total of 106 outpatients were subjected for colonscopy. Carcinoma biopsies from patients with colorectal cancer tissue from patient with polyps and normal mucosa stool and blood from all patient and controls were cultured and identified for S.bovis.
Results: - The histopatholgical findings confirmed that 38 patients had colorectal carninoma, 27 patients with benign polyps and 41 with normal colonic mucosa. The faecal carriage rate of S.bovis was 15(39.5%) in patient with colorected cancer, 5(18.5%) in patients with polyp and 7(17.1%) in control.
Conclusion: -