Background: Bone mineral density (BMD) has been assessed using Dual-Energy X-ray absorptiometry (DEXA). This procedure is considered to be of vital importance in assessing the general condition of individuals concerning their skeletal mineralization. BMD is measured according to the results of the DEXA examination of the vertebral column and pelvis. Although diabetes mellitus (D.M.)is known to affect BMD, the information regarding this relationship is not currently particularly clear. Objective: This study concentrates on the point that the assessment of BMD for the vertebral column is insuffi-cient to give a realistic and correct picture of the mineralization of the remaining part of the skeleton. Besides, this study elicited a generalized view of the mineralization of the different body parts between genders and between the left and right sides of the body. The effect of DM I on BMD was evaluated well in this research. Method: This study involved 165 patients complaining of bone pain (85 male and 80 female), about half of whom suffered from diabetes, involving both genders. Further, 90 healthy volunteers had been studied and were considered to constitute the control group. All individuals (255) in this study were exposed to the study of their BMD via DEXA for all parts of the body. Results: The DEXA exam revealed highly statistically significant differences between the sides of the body in the same subject. In addition, there were significant differences in BMD between females and males and highly statistically significant differences between the control and patient groups with DM I. Finally, this study offered strong evidence that the BMD of the vertebral column and pelvis did not give an accurate picture of mineralization in the different parts of the body for a given subject. In conclusion, the DEXA scan for the whole body and each part separately shows promising results as alternative parameters of the DEXA scan for the spine or hip only for accurate diagnosis. Our results indicate that the BMD of the left and right sides for women was less than for men in all cases (average, osteoporosis, and DMI with osteoporosis) for the same sides and between their upper and lower limbs. Patients with DMI revealed significant reductions in BMD in comparison with other subjects who were not diabetic, even if they had osteoporosis. Keywords: DEXA scan, Osteoporosis, DMI, BMD
This study designed to examine association between-174G/C polymorphism of interleukin-6 gene and phosphate, calcium, vitamin D3, and parathyroid hormone levels in Iraqi patient with chronic kidney disease on maintenance hemodialysis. Seventy chronic renal failure patients (patients group) and 20 healthy subjects (control group) were genotyped for interleukin-6 polymorphism and genotyping was performed by conventional polymerase chain reaction-restriction fragment length polymorphism. No significant differences in phosphate levels were observed in patients and control with different interleukin-6 genotypes. Control had non-significant differences in calcium levels, while patients with GG and CG genotypes displayed significant e
... Show MoreIn this research, we study the dynamics of one parameter family of meromorphic functions . Furthermore, we describe the nature of fixed points of the functions in ,and we explain the numbers of real fixed points depending on the critical point . So, we develop some necessary conditions for the convergence of the sequence when .
Objective: Atorvastatin therapy is now recommended for reduction of cardiovascular risk in type 2 diabetic patients (T2DM), based on convincing evidence of reductions in mortality and vascular events in major clinical outcome trials. The aim is to evaluate the effects of atorvastatin on proinflammatory markers (TNF-α, IL-6), HbA1c andleptin in obese patients with type 2 diabetes. Methods: Sixty fivenewly diagnosed T2DM patients were randomly allocated into 2 groups; group I treated with metformin only; in group II atorvastatin was added with metformin. Twenty healthy subjects were enrolled as control group. While maintaining their usual eating habits, fasting blood samples were collected at baseline and after 12 weeks of treatment. Results
... Show MoreObjectives: Teenage pregnancy with gestational diabetes mellitus (GDM) offers a real challenge to the health system and needs a special care. We aimed to evaluate possible obstetrical and neonatal adverse events of different treatment protocols in adolescent GDM including lifestyle, metformin (MTF), and insulin. Methods: All teen pregnant women ≤ 19 years old visiting Baghdad Teaching Hospital throughout four years (from June 1, 2016 till May 31, 2020) diagnosed with GDM were included in this cohort study and followed-up closely throughout pregnancy and after delivery. Included adolescents were put on lifestyle alone during the first week of presentation. Adolescents who reached target glucose measurements were categorized i
... Show MoreBackground: to evaluate subcutaneous pancreatic transplantation in an experimentally induced diabetes mellitus in golden hamsters.
Methods - many indexes (histological /using two stains, histochemical /using three enzymes, morphometrical and biochemical /blood glucose level) were employed in this assessment. Alloxan was used as ß-cytotoxic therapy (to induce diabetes mellitus), and cyclophosphamide was employed as immunosuppressive agent.
Results - high rate of success of transplantation (clearly evident by microscopical features of viable endocrine and exocrine tissue of transplanted pancreas and great tissue vascularization, normal enzymatic activities and significant lowering of blood glucose level
Abstract: Recombinant human bone morphogenetic protein-2 (rhBMP-2) and platelet-rich fibrin (PRF) bioactive materials have been used to enhance healing and improve dental implant stability. This study aimed to compare the effect of rhBMP-2 and PRF bioactive materials on dental implant stability at different intervals and to evaluate the correlation of implant length and diameter with implant stability. Two bioactive materials were compared to evaluate their effect on dental implant stability. A total of 32 patients (102 dental implants) were divided into 3 groups: 24 dental implants with bone morphogenetic protein (BMP), 27 dental implants with PRF, and 51 dental implants without BMP or PRF (control group). Data were statistically analyzed
... Show MoreDiabetes is a disease caused by high sugar levels. Currently, diabetes is one of the most common diseases in the number of people with diabetes worldwide. The increase in diabetes is caused by the delay in establishing the diagnosis of the disease. Therefore, an initial action is needed as a solution that requires the most appropriate and accurate data mining to manage diabetes mellitus. The algorithms used are artificial neural network algorithms, namely Restricted Boltzmann Machine and Backpropagation. This research aims to compare the two algorithms to find which algorithm can produce high accuracy, and determine which algorithm is more accurate in detecting diabetes mellitus. Several stages were involved in this research, including d
... Show MoreBoth type 1 diabetes and type 2 diabetes have a genetic component, with over 60 chromosomal regions related to type 1 diabetes and over 200 connected with type 2 diabetes at significant genome-wide levels. Numerous single nucleotide polymorphisms in the RETN gene and genetic variables can account for up to 70% of the variations in circulating resistin levels. The RETN polymorphism has been linked in numerous studies to obesity, insulin sensitivity, type 2 diabetes, and cerebrovascular illness. Our objective is to compare this RETN gene 3ʹ-untranslated region polymorphism in type 1 diabetes and type 2 diabetes Iraqi patients. We choose 51 type 1 diabetes and 52 type 2 diabetes patients against 50 healthy subjects (control group) to investig
... Show MoreCorrelation of Serum levels of Chromium, Copper, and Manganese with the Glucose levels in Type 2 Diabetes Mellitus in Ira
Background: The metabolism of many trace elements such as chromium, copper, and manganese were reported to be altered in type 2 diabetes militates. This element may have specific roles in the pathogenesis and progress of this disease.
Objectives: To evaluate the serum levels of copper, chromium, and manganese in type 2 diabetic patients in Iraq.
Patients and Methods: This case-control study included 100 type 2 diabetic patients, 35-60 years old, with high BMI as cases, and 100 non-diabetic subjects as controls who were healthy
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