This study was designed to investigate the hypoglycemic and hypolipidemic activity of aqueous green tea (GT) extract in normal and alloxan-induced diabetic rats. Forty adult male albino rats weighing 180-200 g were divided into four groups of 10 rats each: The first group was served as control; the second group was treated with GT (250 mg/kg b.w); the third group was affected by inducing experimental diabetes by intraperitonial injection of alloxan (150 mg/kg b.w); and the fourth group was affected by inducing diabetes and treated with GT (250 mg/kg b.w). Level of blood glucose and lipid profile [total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and very low-density lipoprotein cholesterol (VLDL-C)] were evaluated at the ending of the experimental period which was designed for 4 weeks. The results revealed that blood glucose level was significantly (P < 0.05) less in the GT-treated group than in the control. Also, diabetic rats treated with GT showed a significant (P<0.05) reduction in blood glucose level when compared with diabetic group. Levels of TC, TG, LDL-C and VLDL-C were significantly (P < 0.05) lower while the level of HDL-C was significantly (P < 0.05) higher in the GT treated group than that in the control. There was a significant (P<0.05) increase in levels of TC, TG, LDL-C and VLDL-C and a significant (P<0.05) decrease in level of HDL-C in diabetic rats when compared to the control group. However, administration of GT extract restored the levels of serum lipids to normal values.
Background: The effect of garlic extracton fungal
growth and keratinolytic activity was studied in
Trichophytonmentagrophytes as one of the major
etiologic agents of human and animal dermatophytosis
in Baghdad and other parts of the World.
Objective: To investigated an alternative
antidermatophyte with minimum side effects which is
plant based and biodegradable natural product
Methods: Culture conditions for 30 isolates of T.
mentagrophytes isolated from human dermatophytosis
from both sexes with ages of 5-63 years in Central
Medical city for the period July 2009 to October 2009
were cultured on specific solid medium.
Results: The aqueous extract of garlic at various
concentrations inhibited the
Green synthesis of silver nanoparticles (AgNPs) using different plant parts has shown a great potential in medicinal and industrial applications. In this study, AgNPs were in vitro green synthesized using A. graecorum, and its antifungal and antitumoractivities were investigated. Scanning electron microscopy (SEM) image result indicated spherical shape of AgNPs with a size range of 22-36 nm indicated by using Image J program. The functional groups indicated by Fourier-transform infrared spectroscopy (FTIR) represented the groups involved in the reduction of silver ion into nanoparticles. Alhagi graecorum AgNPs inhibited MCF-7 breast cancer cell line growth in increased concentration depend manner, significant differences shown at
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This st4dy has been ccil'nd·ucted· to ·shed a1ight 00: the
tox:icologital ®d irmm.J,nological effects.of the insectiCide Diaziuon
on male albino mice.
In order to determine the dose whiCh should be ut\lized in he
chrqn:ic exposure study, the LD:so valubas established which rea.ched
58 mg l kg of b0dy weight . Various parameters were· utHizea in
- evaluatitig'the effects of tb:e.·ins.ecticide in fo.ut Weeks ami ig}1t weeks
..p,ost ora.l - e.xposure l'lsing the concentrations 5, lb- l.5 · mg I kg body
The study conducted to demonstrate the effect of copper nanoparticles (Cu-NPs) on the seminal vesicle and testosterone hormone of males' albino mice. Twenty mice were used and divided into four groups control group and three groups that orally administrated with 100 mg/kg Cu-NPs for 7, 14 and 21 days and each group have 5 animals. Then, the blood was withdrawn from the animals to measure the level of the hormone testosterone in the next day after all the dosages period and then the animal was sacrificed. Seminal vesicles isolated from each animal and measured weight then histological sections were prepared to observe the changes of seminal vesicles sections. Then the morphometric was carried out to the lining cells and their nucleus and
... Show MoreBackground: Hypothyroidism is a decrease in the production of the thyroid hormones and leads to gland dysfunction. Ashwagandha extract was used as an ayurvedic treatment and supposed to be as antihypothyroidism agent.
Objectives: to investigate the impact of ashwagandha (Ash) extract on propylthiouracil (PTU)-induced hypothyroidism in rats.
Subjects and Methods: The rats were divided into three groups, control group, PTU (hypothyroid) group (6mg/kg/day by oral route), PTU (6mg/kg/day by oral route) +Ash (50mg/kg/day by oral route) treated group. All treatment continued for
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The present study aimed to investigate the morphological description and histological structure of kidney in adult albino mice (Mus musculus), The anatomical study revealed that the kidney in albino mice is represented by bean-like shape, smooth with red to brown color, It is situated within the anterior half of abdominal cavity under the diaphragm on both sides of vertebral column. The kidney is covered by capsule of loose connective tissue with mean thickness of (9.6±0.5) micrometer. Histological examination revealed that albino mice kidney tissue differentiated into cortex and medulla, the cortex contains glomeruli with mean diameter of (50.5±1.9) micrometer densely distributed at the peripheral area of the cortex ,
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