BACKGROUND: CRC is one of the most common cancers in the world. K-ras is proto-oncogene with GTPase activity that is lost when the gene is mutated. Analysis of K-ras mutational status is very important for CRC treatment, being the most important predictors of resistance to targeted therapy. OBJECTIVE: This study aims to determine the frequency and spectrum of K-ras mutation among Iraqi patients with sporadic CRC. PATIENTS, MATERIALS AND METHODS: This study enrolled 35 cases with sporadic CRC; their clinicopathological parameters were analyzed. The FFPE blocks were used for DNA extraction; PCR amplification of K-ras gene and hybridization of allele-specific oligoprobes were performed. The assay covers 29 mutations in the K-ras gene (codons 1

The research seeks to identify the dimensions of creative thinking and its impact on the re-engineering of hotel service operations by analyzing the correlation and impact between research variables as well as comparing the research sample The importance of the research comes from the need to motivate managers the importance of creative thinking among workers in the researched hotels because it is an essential part in the re-engineering of hotel services. To achieve this a questionnaire was designed containing (33) items that include the independent research variables (creative thinking) and the accredited (re-engineering the hotel service) and distributed to a sample of (50) individuals represented by (Commissioner Director, Dep

Basket ball game is one of the collective game that practiced widely with continuous developing .Through it has four chase .it required from it’s the player to have number of physical capable. One of these is endurance of strength in order to perform defense and attack duties. The problem is declining the level of this capable that hands inverting to defence and attack performance. The aim of research is to know the effect of using various exercises in developing endurance of strength and effect in developing two skills. dragging of defense and movement of defender player. The two researchers proposed that there are differences that have statistic function between post-test and pre-test for two experimental and control groups. The experim

يعود اهتمام العالم بالبيئة الى التدهور والتغيرات المستمرة جراء الاستغلال البشري الخاطئ لها من خلال رمي المخلفات وبأنواع مختلفة اذ ان البيئة المائية تتعرض يوميا الى الاف الاطنان من المخلفات المختلفة التي أدت الى تلوثها وتزداد هذه الملوثات يوما بعد يوم ومما يؤدي الى الاضرار في البيئة المائية ،و تعد الأنهار المصدر الأساسي للحياة الطبيعية ولكون نهر الفرات احد اهم المصادر المائية وتعتمد عليه العديد من الف

إننا نتحدث عن عناصر السرعة مهمة وهي السرعة الانتقالية للأطراف السفلى والسرعة الحركية للذراع المسلحة والسرعة الحركية للطعن وسرعة رد الفعل وسرعة الاستجابة في أداء واحد او ما يسمى بالسرعة التفاعلية؛ لذا هدفت الدراسة الى اعداد تدريبات خاصة تتميز بتمازج أنواع السرعة التي تحتاجها رياضة المبارزة في أداء واحد ومن ثم معرفة تأثير تلك التدريبات في تطوير بعض الجمل الحركية في سلاح الشيش وقد استعمل المنهج التجريبي