Schiff Bases and Their Metal Complexes Derived from Ortho-phthalaldehyde: A review
Trimethoprim
Amino acids
Schiff base
Bioactivity
Metal complexes
Trimethoprim derivative Schiff bases are versatile ligands synthesized with carbonyl groups from the condensation of primary amines (amino acids). Because of their broad range of biological activity, these compounds are very important in the medical and pharmaceutical fields. Biological activities such as antibacterial, antifungal and antitumor activity are often seen. Transition metal complexes derived from biological activity Schiff base ligands have been commonly used.
