Objective: Zerumbone (ZER) is a well-known natural compound that has been reported to have anti-cancer effect. Thus, this study investigated the ZER potential to inhibit Thymidine Phosphorylase (TP) and the ability to trigger Reactive oxygen species (ROS)-mediated cytotoxicity in non-small cell lung cancer, NCI-H460, cell line. Material and Method: The antiangiogenic activity for ZER was evaluated by using the thymidine phosphorylase inhibitory test. Reactive oxygen species (ROS) production was determined via DCFDA dye by using flow cytometry. Result and Discussion: ZER was found to be potent TP inhibitory with the IC50 value of 50.3± 0.31 μg/ml or 230±1.42 µM. NCI-H460 cells upon treatment with ZER produced sign

Objective: Zerumbone (ZER) is a well-known natural compound that has been reported to have anti-cancer effect. Thus, this study investigated the ZER potential to inhibit Thymidine Phosphorylase (TP) and the ability to trigger Reactive oxygen species (ROS)-mediated cytotoxicity in non-small cell lung cancer, NCI-H460, cell line. Material and Method: The antiangiogenic activity for ZER was evaluated by using the thymidine phosphorylase inhibitory test. Reactive oxygen species (ROS) production was determined via DCFDA dye by using flow cytometry. Result and Discussion: ZER was found to be potent TP inhibitory with the IC50 value of 50.3± 0.31 μg/ml or 230±1.42 µM. NCI-H460 cells upon treatment with ZER produced sign

  The experimentes were carried out by using a nutrient solution in the green house of Biology Dept , college of Education (Ibn Al- Haitham , University of Baghdad .) during 2001 -2002 growing season in order to determine the effect of sodium ion, by using four concentrations: (zero , 40,80,120. Mm), to study the appearance and physiological characteristics for two wheat varieties : IP A99 and Al-Kaid according to factorial experiment in completely randomized design for each concentration. The rcsults showed that the fourth concentration (120 Mm) for the Na ion is the most effective one on Leaf area, chlorophyll content, soluble carbohydrates, nitrogen content and protein percentage.        Moreove

The central nervous system is the most important system and is very sensitive to any accidental infection during ontogenesis; it includes brain and spinal cord. The cerebellum is the second largest part of the brain after cerebrum and it’s very sensitive to the abnormal changes during the embryological development. This study was designed to investigate the effect of the maternal exposure of selected concentrations of suspension of nanoparticles on the ontogenesis of the rat cerebellum after embryos implanted in uterus. A total of 60 female pregnant rats were divided in to three groups, each contains 20 females. Group1 (G1) was treated orally with 2mg/kg /body weight (b. wt) of suspension of silver nanoparticles (Ag NPs). While group 2 (G

  The study current included histological structure of stomach of Liza abu , anatomical results found that stomach represent the expander non-convoluted part of gastrointestinal tract it is located between the end of the esophagus and the beginning of the intestine , the average length of stomach was (1.5) cm , composed of two parts : cardiac stomach which is represent the anterior part and be thin- walled , the other part was pyloric stomach or gizzard and the walls were thick . The internal surface of cardiac and pyloric stomach contain longitudinal folds numbering (7), folds branching to finger shape structures extend inside the lumen . Histological study showed that stomach wall composed of three main histological layers : mucos

  The study includes histological structure of  digestive tract of  Liza abu , Anatomical results found that the digestive tract occupied the largest part of  abdominal cavity ,  the mean gut length was (45.5) cm and relative gut length was (2.9) .  esophagus was a muscular tube length (1.5) cm , esophagus wall containing longitudinal  straight unbranched folds numbering (9) . Histological study  results found that the esophagus composed of four tunica : mucosa , submucosa , muscularis and serosa . The results found that the mucosa consists of three layers : epithelium , lamina propria and muscularis mucosa . The epithelial layer was stratified squamous epithelium thickness (139.1) µ containing

Allium ampeloprasum extract has the potential to facilitate wound healing due to its anti-inflammatory, antioxidant, and antibacterial properties. In this study, we aimed to investigate the potential wound-healing activity of the methanol extract derived from Allium ampeloprasum. Using 30 healthy male Wester rats; control group: 15 rats; normal saline applied locally instead of plant-extract. Experimental group: 15 rats received a daily local application of 200 mg/kg of the plant extract. Then, for each healing period of 0, 5, or 10 days, each group was divided into three-subgroups: A, B, and C, each with five rats. There was a significant difference in the percentage of wound contraction between the control and experimental groups (p 0.02)

 The study includes histological structure of  pyloric caeca , intestine and rectum of Liza abu , the results show that the pyloric caeca are non-branched fingerlings structures numbering (4) and length rate was (0.5) cm , while the intestine of Liza abu was long narrow tube composed of a number of laps , the anterior part of intestine was wider in diameter than the posterior part , the length of intestine was (32) cm , the rectum was straight tube extends from the end of posterior part of intestine to the anus.         The wall of pyloric caeca , intestine and rectum consists of main layers : mucosa , submucosa , muscularis and serosa , lining epithelium of  pyloric caeca , intestin