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The purple pigment violacein is produced by Gram-negative bacteria, mainly
from the Chromobacterium violaceum. Violacein is synthesized by fusing two Ltryptophan
molecules using five different enzymes encoded by VioA, VioB, VioC,
VioD, and VioE genes. These genes have transferred to genetically engineering
microorganisms such as E.coli for high production of violacein. It is receiving
greater interest because of its significant biological functions and therapeutic potential.
The reviews outlining the biosynthesis, production, and biological significance
of violacein are being published.