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Cord Blood Sex Hormones Concentration: Relation to Birth Weight and Pregnancy Complications

Objectives: Umbilical cord blood can be taken at birth and largely gives indication of fetal and maternal conditions. The aim of the study was to investigate the relation between sex hormones in cord blood and birth weight of newborns and pregnancy complications. Methods: Fifty cord blood samples were collected from newborns at labor room of Baghdad Teaching Hospital between May and October 2018. Blood was withdrawn from their mothers for lead analysis. Five milliliters (ml) of cord blood was taken, 3 ml was used for testosterone and estradiol analysis (using enzyme-linked immunosorbent assay) and 2 ml for lead measurement by lead care analyzer. Newborns weight and head circumference were measured. Delivered women were divided into four groups: Women with normal pregnancy, women with pre-eclampsia, diabetic women and polycystic ovary syndrome (PCOS) women. Results: There was no significant difference in age between women in all groups (P > 0.05). Birth weights, estradiol, and testosterone were significantly different between groups. Estradiol was higher in cord blood of newborns of PCOS women (P < 0.05) than others. Testosterone was higher in cord blood of babies of PCOS and pre-eclampsia women compared with those of diabetes (P < 0.05). There were no significant differences between male and female neonates regarding cord estradiol (3596.27 ± 1934.69, 3714.57 ± 1581.47 pg/ml respectively), and testosterone (393.18 ± 87.14, 361.43 ± 102.14 ng/ml respectively) (P > 0.05). Maternal lead levels correlated positively with cord lead (r = 0.905, P < 0.05), which correlated negatively with head circumference (r = −0.766, P < 0.05). Birth weight correlated negatively with estradiol (r = −0.295), but positively with testosterone (r = 0.006) (P > 0.05). Conclusion: Cord blood estradiol and testosterone levels do not differ between males and females. Estradiol was high in cord blood of PCOS mothers. Testosterone was high in cord blood of PCOS and pre-eclampsia mothers. The increase in cord lead causes decrease in babies head circumference.

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Publication Date
Fri Sep 01 2023
Journal Name
Journal Of Coloproctology
The Impact of Smoking on the Complications of Acute Appendicitis
Abstract<p> Introduction The pathophysiology of appendicitis likely stems from obstruction of the appendiceal orifice leading to an increase in intraluminal and intramural pressure, resulting in small vessel occlusion and lymphatic stasis. Organ supplied by an end artery, such as the appendix, are more prone to the deleterious effects of arterial occlusion. The continuous cigarette smoking might be associated with a greater risk for developing atherosclerosis.</p><p> Objectives The aim is to evaluate the effect of cigarette smoking on the incidence of complications of acute appendicitis.</p><p> Methods Patients suffered from symptoms and signs suggesting a</p> ... Show More
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Publication Date
Sun Sep 15 2024
Journal Name
Iraqi Journal Of Pharmaceutical Sciences( P-issn 1683 - 3597 E-issn 2521 - 3512)
Biomarkers of Oxidative Stress in Diabetic Microvascular Complications Review Article

Reactive oxygen species (ROS) are produced as a result of biochemical processes that are not in balance with the body's antioxidant defense mechanism. This metabolic dysfunction is referred to the oxidative stress (OS).  Metabolic dysfunction-associated diseases are affected by changes in the redox balance. It is now widely recognized that oxidative stress significantly affects diabetes mellitus (DM), particularly type 2 diabetes. The biochemical changes associated with  DM could  disturb the oxidative milieu, leading to several microvascular complications in diabetic patients. Thus, DM is a perfect disease to explore the harmful consequences of oxidative stress and how to treat it. Oxidative stress triggered by hyperglycemia is

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Publication Date
Wed Jan 02 2013
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Physiological Changes In Spirometric Parameters During Pregnancy In Iraqi Women

Background: The events in pregnancy elicit one of the best examples of selective anatomical, physiological and biochemical adaptations, with profound changes in respiratory physiology. The changes in respiratory  physiology are due to increased  size of the fetus with advance  gestation which constitutes a mechanical impediment to normal process of ventilation.

.Patients and methods: This study started from the 1st of Nov.  2009 till the 30th of Oct. 2010. pregnant women aged (16-44 years) of different weight, height and different conception from 1st, 2nd, 3rd trimester and post term were included. Spirometry was performed in Baghdad teaching hospital( pulmonary fun

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Publication Date
Sun Jan 01 2017
Journal Name
Journal Of Research In Medical Sciences
Procalcitonin levels and other biochemical parameters in patients with or without diabetic foot complications

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Publication Date
Thu Oct 01 2015
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Single Burr Hole Craniostomy in surgical treatment of chronic subdural hematoma (Outcome and Complications)

Background: There is controversy among neurosurgeons whether double Burr Hole craniostomy is better than single Burr Hole, craniostomy in the management of chronic subdural hematoma in terms of lower recurrence rate and complications.
Objective: To assess the outcome and complications including revision rate using Single Burr Hole Craniostomy in the treatment of chronic subdural hematoma (CSDH).
Patients and Methods: This is a retrospective study of 42 cases of chronic subdural hematoma who underwent Single Burr Hole Craniostomy(SBHC) from jan.2012 to jan.2014, preoperative,intraoperative and postoperative data were collected including neurological status ,Brain CT-scan findings, postoperative complications ,recurrent rate and neur

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Publication Date
Tue Jun 30 2015
Journal Name
Al-kindy College Medical Journal
Weight loss program outcome of obese attending AL-Kindy obesity research and therapy unit

Background: overweight and obesity are the fifth leadingrisk for global deaths. At least 2.8 million adults die eachyear as a result of being overweight or obese. Numerousstudies show that weight loss, even if only 5-10%,significantly improves dyslipidemia, hypertension, diabetesmellitus, risk for osteoarthritis and its symptoms and risk forselected cancers.Objectives: is to evaluate the effect of diet and exerciseprogram on anthropometric and biochemical status of adultobese patients.Methods: descriptive study. 124 adult obese patientsattending Al Kindy obesity research and therapy unit duringDecember 2012 were included. Measurement of Wt, heightHt and WC performed and BMI was calculated. Laboratorytest analysis, on the fasting state, w

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Publication Date
Thu Apr 18 2019
Journal Name
Al-kindy College Medical Journal
Maternal knowledge related to anemia during pregnancy among a sample of mothers attending Primary Health Care centers. Baghdad.

Background: Anaemia is a major public health concern and is one of the most prevalent health issue in women within reproductive age group.

Objective: to assess maternal knowledge related to anaemia during pregnancy.

Type of the study: A cross –sectional study.

Method: The study including 200 mothers who attended selected primary health care centres, Baghdad during November and December 2015, they completed a previously prepared questionnaire coveringsocio-demographic characteristics and knowledge regarding anaemia in 4 main domains. The responses were analysed by using frequency, percentage and percent score for each statement a

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Publication Date
Wed Aug 07 2019
Journal Name
Iraqi National Journal Of Nursing Specialties
Impact of Factors upon Children’ Weight Status of age one to Five years old at Primary Health Care Centers in AL Samawah City

Objective: The study aim is to identify factors that may contribute to children’s weight status variations. Methodology: A descriptive cross sectional study is carried out has been conducted at the AL- Samawah city in Primary Health Care Centers for the purpose of the screening children’s weight status of Age One to five Years Old. This study is started from December 16th 2018 to February 14th 2019. A(non propriety) purposive sample comprised of (20) primary health centers (10 main and 10 sub) are selected of 500 children who visit the primary health care center during the period for the purpose of the study; Data was collected through using a questionnaire designed and developed for the purpose of the study . It consists of two main

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Publication Date
Thu Mar 30 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
The Effect of Chronic Renal Failure on Thyroid Hormones

       Chronic renal failure (CRF) affects thyroid function in multiple ways, including low circulating thyroid hormone concentration, altered peripheral hormone metabolism, disturbed binding to carrier proteins, possible reduction in tissue thyroid hormone content, and increased iodine store in thyroid glands.The target of study is to find a relationship between chronic renal failure and thyroid function.In addition, we tried to study the effect of CRF on serum creatinine dependent on the level of thyroid hormones (T3 and T4) and thyroid stimulating hormones(TSH). Forty patients with chronic renal failure (20 male, 20 female) were enrolled in this study in addition to forty healthy individual as control gro

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Publication Date
Sat Jun 15 2019
Journal Name
Journal Of Baghdad College Of Dentistry
Perineural Invasion in Oral Squamous Cell Carcinoma in Relation to Tumor Depth

Background: The American Joint committee on Cancer in their 8th edition staging manual regarded perineural invasion as one of the most important prognostic factors for Lip and Oral Cavity Squamous Cell Carcinoma, it also incorporated tumor depth of invasion in defining tumor size category in the new staging system. This study was conducted to evaluate the frequency of perineural invasion in oral squamous cell carcinoma and the effect of approaching tumor depth in this process. Materials and Methods: fifty-four formalin fixed paraffin embedded tissue blocks of radical resections of Oral Squamous Cell Carcinoma were cut and stained with Hematoxylin and Eosin stain, then evaluated for perineural invasion, with estimation of tumor depth of i

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