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Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism
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Here we determined the structure of a cold active family IV esterase (EstN7) cloned from Bacillus cohnii strain N1. EstN7 is a dimer with a classical α/β hydrolase fold. It has an acidic surface that is thought to play a role in cold-adaption by retaining solvation under changed water solvent entropy at lower temperatures. The conformation of the functionally important cap region is significantly different to EstN7's closest relatives, forming a bridge-like structure with reduced helical content providing greater access to the active site through more than one substrate access tunnel. However, dynamics do not appear to play a major role in cold adaption. Molecular dynamics at different temperatures, rigidity analysis, normal mode analysis and geometric simulations of motion confirm the flexibility of the cap region but suggest that the rest of the protein is largely rigid. Rigidity analysis indicates the distribution of hydrophobic tethers is appropriate to colder conditions, where the hydrophobic effect is weaker than in mesophilic conditions due to reduced water entropy. Thus, it is likely that increased substrate accessibility and tolerance to changes in water entropy are important for of EstN7's cold adaptation rather than changes in dynamics.

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Publication Date
Wed Aug 09 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
On Weakly Prime Submodules
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Let R be a commutative ring with unity and let M be a left R-module. We define a proper submodule N of M to be a weakly prime if whenever  r  R,  x  M, 0  r x  N implies  x  N  or  r  (N:M). In fact this concept is a generalization of the concept weakly  prime ideal, where a proper ideal P of R is called a weakly prime, if for all a, b  R, 0  a b  P implies a  P or b  P. Various properties of weakly prime submodules are considered. 

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Publication Date
Sat Mar 11 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
á´ª-Prime Submodules
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      Let R be a commutative ring with identity and M be an unitary R-module. Let (M) be the set of all submodules of M, and : (M)  (M)  {} be a function. We say that a proper submodule P of M is -prime if for each r  R and x  M, if rx  P, then either x  P + (P) or r M  P + (P) . Some of the properties of this concept will be investigated. Some characterizations of -prime submodules will be given, and we show that under some assumptions prime submodules and -prime submodules are coincide. 

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Publication Date
Wed Nov 27 2019
Journal Name
Iraqi Journal Of Science
I-Nearly Prime Submodules
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     Let  be a commutative ring with identity, and a fixed ideal of  and  be an unitary -module. In this paper we  introduce and study the concept of -nearly prime submodules as genrealizations of nearly prime and we investigate some properties of this class of submodules. Also, some characterizations of -nearly prime submodules will be given.

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Publication Date
Sat Oct 30 2021
Journal Name
Iraqi Journal Of Science
N Sequence Prime Ideals
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    In this paper, the concepts of -sequence prime ideal and -sequence quasi prime ideal are introduced. Some properties of such ideals are investigated. The relations between -sequence prime ideal and each of primary ideal, -prime ideal, quasi prime ideal, strongly irreducible ideal, and closed ideal, are studied. Also, the ideals of a principal ideal domain are classified into quasi prime ideals and -sequence quasi prime ideals.

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Publication Date
Sun Jul 09 2023
Journal Name
Journal Of Engineering
Parametric Study of Active Solar Heating Using a Pebble Bed as a Thermal Collector and Storage Unit
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In this study, pebble bed as an absorber and storage material was placed in a south facing, flat plate air-type solar collector at fixed tilt angle of (45°). The effect of this material and differ- ent parameters on collector efficiency has been investigated experimentally and
theoretically. Two operation modes were employed to study the performance of the solar air heater. An inte- grated mode of continuous operation of the system during the period of (11:00 am – 3:00 pm) and non-integrated mode in which the system stored the solar energy through the day then used the stored energy during the period of (3:00 pm – 8:00 pm). The results of parametric study in case of continuous operating showed that the maximum average temperatur

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Publication Date
Thu Feb 01 2018
Journal Name
Association Of Arab Universities Journal Of Engineering Sciences
Effects of Properties and Simulations for Dry Granular Soils on Buckling Loads of Portal Frames
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Publication Date
Mon Oct 01 2018
Journal Name
Ieee Transactions On Network Science And Engineering
A Resource Allocation Mechanism for Cloud Radio Access Network Based on Cell Differentiation and Integration Concept
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Publication Date
Fri Dec 27 2024
Journal Name
Journal Of Baghdad College Of Dentistry
Teeth Displacement and Palatal Adaptation of Autoclave Cured acrylic resin with Various Palates and Investments.
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Background: The denture base inaccuracies during processing negatively influence the retention and stability of finished complete denture. The aims of this study were to evaluate teeth movement and palatal adaptation of autoclave cured denture bases and their relationship with palatal depths and investments. Materials and methods: A nightly maxillary complete dentures prepared, processed and organized to be tested as follows: 1. Processing methods: water bath and autoclave with both fast and slow cycles. 2. Palatal depth: shallow, medium and deep. 3. Investing medium: stone and silicone. For every finished denture, two measurements were done: first: teeth movement by attaching metallic reference screws on the right and left centrals, first

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Publication Date
Tue Apr 04 2023
Journal Name
Results In Nonlinear Analysis
The fractional integrodifferential operator and its univalence and boundedness features according to Pre-Schwarzian derivative structure
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Complex-valued regular functions that are normalized in the open unit disk are vastly studied. The current study introduces a new fractional integrodifferential (non-linear) operator. Based on the pre-Schwarzian derivative, certain appropriate stipulations on the parameters included in this con-structed operator to be univalent and bounded are investigated and determined.

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Publication Date
Tue Sep 29 2020
Journal Name
Iraqi Journal Of Science
A Jordan Higher Reverse Left (resp. right) Centralizer on Prime -Rings
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In this paper,  we introduce the concepts of  higher reverse left (resp.right)   centralizer, Jordan higher reverse left (resp. right) centralizer, and Jordan triple higher reverse left (resp. right) centralizer of  G-rings. We prove that every Jordan higher reverse left (resp. right) centralizer of a 2-torsion free prime G-ring M is a higher reverse left (resp. right) centralizer of  M.

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