Chronic myelogenous leukemia (CML) is a myeloproliferative neoplasm arises from Bcr-Abl gene translocation(called Ph chromosome) in hematopoietic stem cells (HSCs).JAK2V617F mutation is an acquired singlenucleotide polymorphism (SNP) occurs in JAK2 gene and is associated with many hematological malignancyother than CML. This study aimed to investigate the prevalence of JAK2V617F mutation and serum levels ofalkaline phophatase (ALP) and lactate dehydrogenase (LDH) in Ph+ CML Iraqi patients treated with imatinib.Blood samples were collected from 42 Ph+ CML patients who have been received at least six month therapywith imatinib. DNA was extracted, and real time polymerase chain reaction (qPCR) was used for JAK2V617Fdetection. Serum levels of ALP and LDH were measured using ready kits. Five of 43 CML patients (11.62%)had heterozygous mutant allele of JAK2V617F mutation, with a concentration ranged from 0.01% to 0.12%. Theprevalence of this mutation is more associated with male than female (OR=0.5, 95%CI=0.364-0.687).JAK2V617F-positive patients had higher average serum levels of ALP and LDH (146.05±8.028 IU/L and 204±10.85 IU/L respectively) than that of JAK2V617F-negative patients (64.45±40.15 IU/L and 178.33±13.693 IU/Lrespectively with significant differences. JAK2V617F mutationcould occur in coexistence with Bcr-Abl transcriptin CML patients, and serum levels of ALP and LDH can be used as indicators for this coexistence .
This research deals with the study of the obstacles to peaceful coexistence in Iraq. Therefore, our hypothesis is that these obstacles are not attributed to one reason or to one source. Therefore, peaceful coexistence among the components of Iraqi society remains fragile and vulnerable to collapse and threat at any moment. This society, which is already in need of social relations, needs more than ever to coexist and consolidate it. Through the exercise of democracy in Iraq in a manner that guarantees rights and duties for all, to restore mutual trust between the components of this community in a way that feels they are citizens of the state.
The study area soils suffer from several problems appear as tkhesvat and cracks in the roads and waterlogging which reduces the susceptibility of soil to withstand pressure, this study was conducted on the soil of the Karkh district based on field study that included (6) samples of soil physical analyses contain different ratios of (mud, sand, silt) as percentages (52%, 45%, 3 #) respectively, and liquidity limit rate (39%) Stroke rate plasticity was (20.6%) The rate coefficient of plasticity total (19.2%)0
The research came in order to take note of the types of inscription and to clarify its provisions and to show some of the possibilities of Islamic law in the sales side and its ability to influence in Islamic markets, and to achieve the required level and appropriate of the transactional results by activating them in economic life, and give a clear picture of the performance of selling in the law and the possibility of applying one of Its uses in this aspect, and enable them to take advantage of the method of explicitly sell without the injustice of others as one of those useful sales uses.
A soliton is a solitary wave whose amplitude, shape, and velocity are conserved after a collision with another soliton. Solitons, in general, manifest themselves in a large variety of wave/particle systems in nature: practically in any system that possesses both dispersion (in time or space) and nonlinearity. Solitons have been identified in optics, plasmas, fluids, condensed matter, particle physics, and astrophysics. Yet over the past decade, the forefront of soliton research has shifted to neuroscience. The Soliton model in optical fiber is a recently developed model that attempts to explain how signals are propagated within optical fiber without dispersion. In this research, it proposes that the signals travel along the Single Mode O
... Show MoreThe values of fmgerprint angles were studied in 57 females and 44 males from Najaf province in the m iddle of Iraq. Some results of tlus sample were compared with the results of Southern provinces sample from Iraq i population.
The rCS\tlts revealed that the mean of maximum fingerprint angle (MFA) and also the mean of absolute fingerprint angle (AFA) between samples in the studied provinces did nnt differ significantly. However, the unilateral analysis revealed only one significant diOerence in LS of the male samples (r-2.89, P<O.Ol), while the bilateral analysis revealed two significant differences, wluch occurred in Rl and R3 of the right hand.
As lbr the compari son between sexes of the
... Show MoreThe current research dealt with the development of sciences and arts over the course of human history, and the development of sciences with their natural and human trends are important areas in developing the knowledge and application base for industrial product design and design in its various fields. Bionic science is one of the sciences that works on applying biological methods and systems found in nature to study and design engineering systems and modern technology, and for industrial products to be highly efficient, durable and resistant to natural variables in daily life for use. The transfer of technology between life forms and industrial products is desirable because the processes of development at the level of science in general
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I have studied the relationship between blood groups in humans and disease Cutaneous injury for the first time in Iraq study showed the presence of a significant statistical relationship between them leather Bmsoy in hospitals in Baghdad and its suburbs
The importance of Public Relations activity has increased during the last half of the last century as a specialized and modern administrative function in most institutions. It has, moreover, become an integral part of activities of those institutions of various types, due to its pivotal role in building its reputation and drawing a good mental image among its audiences, as well as its influential and basic role in maintaining communication and the communication between its members at its various levels and their job tasks to ensure the greatest amount of understanding and to enhance trust between them. This is why public relations activity has become indispensable in all institutions, and without it, it is difficult to achieve any coordi
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The theatrical performance has an aesthetic, artistic, technical and intellectual vision presented by the theatrical director according to the dualities of theatrical form and content, which depend on the uniformity and interconnection of theatrical elements, as the vision is integrated through the harmony and fusion of these elements and the flow of their coordination with an aesthetic system within the framework of the aesthetic space of the theatrical performance, and when the heritage is presented in the performance, as there will certainly be different readings of that heritage and moving away from the iconization of the event and highlighting it in a manner that is in line with the spirit of the age.
the (researcher) tries, t
Anticyclone of synoptic studies that influence weather and climate of Iraq, The aim of
the study is to clarify the effect variation of repetition of Anticyclone and effect on thermal
characteristic in Iraq were pressure level has been analyzed (1000) millibars and that because
of pressure level is the closet to the earth surface and the clarity of climatic phenomenon
based on a systematic analysis of synoptic seeking maps and observation and (12:00)
according to timing GMT for five climatic stations which is (Mosul, Kirkuk, Baghdad, Rutba,
and Basra) and so far three consecutive climatic cycles which is first climatic cycle for period
(1986-1976). and second climatic cycle for period (1997-1987) and third climatic cy