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Bioavailability of Bilastine Oral Self-nanoemulsion: Comparative Study with Commercial Formula in Rats
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Bilastine (BL) is a novel non-sedating second-generation antihistamine, and its bioavailability is about 60%. Objective: To compare the bioavailability of prepared oral self-nanoemulsions of BL (BL-SNE) with that of pure BL and marketed tablets. Methods: Four groups of Wistar rats were used in this study, each with six rats weighing between 200 and 250 g. They were treated orally using a a gavage tube. The groups were fed either with conventional tablets ("Alerbix®") after being ground and dispersed with deionized water (DIW), treated with BL-SNE or fed with pure BL powder suspension. The fourth group did not receive any medication. The concentration of BL in the rat’s plasma was measured using HPLC. We used Trandolapril as an an internal standard. Results: The bioavailability results for the the prepared formula, tablet, and pure BL were 24289.91 ng/ml, 0.75 h, 12.81, 97844.7 ng.h/ml, and 98732.9 ng/ml, respectively, for the BL-SNE formula, and 15840.37, 1.0, 13.014, 66140.4, and 67088.3 for the tablets. Meanwhile, the BL suspension demonstrates 10830.12, 1.0 h, 12.96, 59397.12 ng/ml, and 60534.64 ng/ml, respectively. Conclusions: The relative bioavailability of BL-SNE was 1.47 and 1.6 times higher than that of marketed tablets and pure BL, respectively. This indicates an improvement in BL's bioavailability.

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Publication Date
Thu Feb 01 2018
Journal Name
Journal Of Economics And Administrative Sciences
The role Government Securities Market on the Iraqi Credit worthiness
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تشكل  التغيرات الحاصلة في اسعار النفط تحديا" حقيقيا" لاستمرار عملية النمو في العراق, وامام الحكومة فرصة كبيرة لإيجاد حلول ناجعة لمشكلة تزايد عجز الموازنة العامة من خلال اللجوء الى اصدار ادوات الدين العام الداخلي والخارجي, وهذا يتطلب بناء استراتيجية لإقامة وتطوير سوق السندات الحكومية في العراق, لتتمكن الحكومة من خلاله توفير مصادر تمويل اضافية, تسهم في تمويل الانفاق الاستثماري الحكومي ودعم النمو ودعم

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Publication Date
Thu Dec 05 2019
Journal Name
المجلة السياسية والدولية
دور التنشئة الاجتماعية في تعزيز قيم التسامح والتعايش: العراق انموذجا
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أصبحت التنشئة الاجتماعية السليمة من أكثر الأدوات في التصدي لأوبئـة العنف والتطرف ومظاهرها المتفشية بصورة أو بأخرى في مجتمعاتنـا المعاصـرة عامـة باختلاف أيديولوجياته الفكرية ومعتقداته الدينيـة ومسـتوى نموهـا الاقتصـادي، وأصبحت بأشكالها المتنوعة معنية بترسيخ التعاليم الدينيـة السـمحة وغـرس القـيم الديمقراطية السليمة ومبادئ وقيم حقوق الإنسان في شتى مجالات الحياة الإنسانية، وهي أيضا تعد حجر الأساس من اج

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Publication Date
Wed Apr 01 2015
Journal Name
Journal Of Educational And Psychological Researches
التفكير المزدوج ودوره في تعزيز روح التسامح لدى طلبة الجامعة
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    Sought Current search to know the concepts of modern literature theoretical educational, psychological and social are thinking double and tolerance and the definition of them in the theoretical frameworks of religious, social and psychological to clarify their role in life in general and in university life private and to understand their respective roles in the promotion of the other, and research has included a chapter first to identify the importance and the objectives and terms Search in detail, and a chapter of a second frameworks and theoretical literature of concepts ranging from religious heritage in Islam and other religions, especially the concept of tolerance, then look at social, psy

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Publication Date
Thu Dec 05 2019
Journal Name
السياسية والدولية
دور التنشئة الاجتماعية في تعزيز قيم التسامح والتعايش: العراق انموذجا
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أصبحت التنشئة الاجتماعية السليمة من أكثر الأدوات في التصدي لأوبئـة العنف والتطرف ومظاهرها المتفشية بصورة أو بأخرى في مجتمعاتنـا المعاصـرة عامـة باختلاف أيديولوجياته الفكرية ومعتقداته الدينيـة ومسـتوى نموهـا الاقتصـادي، وأصبحت بأشكالها المتنوعة معنية بترسيخ التعاليم الدينيـة السـمحة وغـرس القـيم الديمقراطية السليمة ومبادئ وقيم حقوق الإنسان في شتى مجالات الحياة الإنسانية، وهي أيضا تعد حجر الأساس من اج

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Publication Date
Sat Feb 01 2014
Journal Name
Journal Of Economics And Administrative Sciences
Concept And Importance Of Detection Failureś Possibilities Of Corporation Proposed Model For Application In The Iraqi Environment
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Research aims to shed light on the concept of corporate failures , display and analysis the most distinctive models used to predicting corporate failure; with suggesting  a model to reveal the probabilities of corporate failures which including internal and external financial and non-financial indicators, A tested is made for the research objectivity and its indicators weight and by a  number of academics professionals experts, in addition to  financial analysts  and have concluded a set of conclusions ,  the most distinctive of them that failure is not considered a sudden phenomena for the company and its stakeholders , it is an Event passes through numerous stages; each have their symptoms that lead eve

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Publication Date
Fri Oct 30 2020
Journal Name
Journal Of Economics And Administrative Sciences
Evaluating the reality of applying the curriculum axis according to the Iraqi academic accreditation standards / a comparative study of a sample of governmental and private universities and colleges
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The research aims to get acquainted with the evaluation of the reality of the application of the curriculum axis from among the eight Iraqi academic accreditation standards in a sample of governmental and private universities and colleges in Iraq and to identify the main and secondary reasons for it as well as to provide proposed mechanisms and procedures to help reduce gaps, If the research problem is represented in the weak availability of the requirements of the curriculum axis in universities and colleges (the study sample) due to the weak documentation and successful implementation of them and interest in them is still below the level of ambition, In order to arrive at scientific facts, the researchers adopted the comparativ

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Publication Date
Wed Jan 01 2020
Journal Name
Biochemical & Cellular Archives
CORRELATION STUDY BETWEEN METHIONINE SYNTHASE, CYSTATHIONINE B SYNTHASE WITH CLASSIC PARAMETERS AFTER TREATED WITH JANUVIA IN IRAQI DIABETIC PATIENT'S TYPE 2 AND COMPLICATION.
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This study was aimed to examined effect of Januvia treatment on methionine synthases Meth and cystathionine B- synthase (CBS) in Iraqi patients type2 without treated and another group who taken Januvia treated in addition to diabetic patients with complication without treated with Januvia Also, to found the relationship between these parameters with BMI, FBS, HbA1C and Insulin levels. Firstly, the blood sampling date for this research between December and February 2019 - 2020. Blood sampling was withdrawn from 8:00 to 10:00 in the case of fasting of all substances . five milliliters of venous blood were collected by means of an antecubital venipuncture divided into two parts, one of which (2ml) was put in a tube containing anticoagulant fac

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Publication Date
Thu Jun 20 2019
Journal Name
Baghdad Science Journal
A Comparative Analysis of the Zernike Moments for Single Object Retrieval
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Zernike Moments has been popularly used in many shape-based image retrieval studies due to its powerful shape representation. However its strength and weaknesses have not been clearly highlighted in the previous studies. Thus, its powerful shape representation could not be fully utilized. In this paper, a method to fully capture the shape representation properties of Zernike Moments is implemented and tested on a single object for binary and grey level images. The proposed method works by determining the boundary of the shape object and then resizing the object shape to the boundary of the image. Three case studies were made. Case 1 is the Zernike Moments implementation on the original shape object image. In Case 2, the centroid of the s

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Publication Date
Wed Dec 01 2021
Journal Name
International Journal Of Research In Social Sciences & Humanities. E-issn
CONCEPTS OF LITERATURE: COMPARATIVE LITERATURE BY HENRY GIFFORD (an Article REVIEW).
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BOOK REVIEW

Publication Date
Mon Apr 23 2018
Journal Name
Elibrary.ru
PHYSICAL FITNESS OF FEMALE STUDENTS FROM IRAQ AND RUSSIA: COMPARATIVE ANALYSIS
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Objective of the study was to rate and analyze the physical fitness of female students from Iraq and Russia to find similarities, differences and regularities. Sampled for the study were 44 female non-sporting students: 20 students from Pedagogical University in Bagdad; and 24 students from Russian State University of Physical Education, Sport, Youth and Tourism in Moscow. The study was designed to obtain the joints flexibility, coordination, speed-strength and static endurance rates. The Iraqi students were tested with higher coordination abilities than their Russian peers, whilst the latter were ranked higher in the speed-strength, shoulder joints and spine flexibility tests, albeit lower than their Iraqi peers in the hip flexibility test

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