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Bioavailability of Bilastine Oral Self-nanoemulsion: Comparative Study with Commercial Formula in Rats
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Bilastine (BL) is a novel non-sedating second-generation antihistamine, and its bioavailability is about 60%. Objective: To compare the bioavailability of prepared oral self-nanoemulsions of BL (BL-SNE) with that of pure BL and marketed tablets. Methods: Four groups of Wistar rats were used in this study, each with six rats weighing between 200 and 250 g. They were treated orally using a a gavage tube. The groups were fed either with conventional tablets ("Alerbix®") after being ground and dispersed with deionized water (DIW), treated with BL-SNE or fed with pure BL powder suspension. The fourth group did not receive any medication. The concentration of BL in the rat’s plasma was measured using HPLC. We used Trandolapril as an an internal standard. Results: The bioavailability results for the the prepared formula, tablet, and pure BL were 24289.91 ng/ml, 0.75 h, 12.81, 97844.7 ng.h/ml, and 98732.9 ng/ml, respectively, for the BL-SNE formula, and 15840.37, 1.0, 13.014, 66140.4, and 67088.3 for the tablets. Meanwhile, the BL suspension demonstrates 10830.12, 1.0 h, 12.96, 59397.12 ng/ml, and 60534.64 ng/ml, respectively. Conclusions: The relative bioavailability of BL-SNE was 1.47 and 1.6 times higher than that of marketed tablets and pure BL, respectively. This indicates an improvement in BL's bioavailability.

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Publication Date
Tue Aug 01 2023
Journal Name
Journal Of Engineering
Review about the Applications of Nanoparticles in Batteries
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Nanoparticles are defined as an organic or non-organic structure of matter in at least one of its dimensions less than 100 nm. Nanoparticles proved their effectiveness in different fields because of their unique physicochemical properties. Using nanoparticles in the power field contributes to cleaning and decreasing environmental pollution, which means it is an environmentally friendly material. It could be used in many different parts of batteries, including an anode, cathode, and electrolyte. This study reviews different types of nanoparticles used in Lithium-ion batteries by collecting the advanced techniques for applying nanotechnology in batteries. In addition, this review presents an idea about the advantages and d

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Publication Date
Sat Dec 01 2018
Journal Name
Political Sciences Journal
Concept of moderation in the Islamic political thought
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Abstract : The concept of moderation is one of the important concepts that have been discussed in political thought in general and in Islamic political thought in particular. It concerns the status of moderation and balance and the need of Islamic societies to apply them in contemporary times. The Islamic societies faced challenges facing Islamic advancement. And the right, which is the middle between the excessive and the excessive -and the exaggeration and cost-, and between negligence and default, moderation and integritybetween both two sides are: excessive and negligent". In addition, the concept of moderation and its intellectual roots have been sought in the Holy Quran and the noble prophetic, and the search for its charac

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Publication Date
Fri Jan 05 2024
Journal Name
Al-academy
Problametic of human body in post modern arts
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Explanation of article events , or discribing it establish to anderstanding an phenomenon which its effects still clear in the art , surching like this may be very usful in the analysis of new art , which considering one of the most important turns in the history of art . and if we look to human body in the art as existenc in the art , from it’s begening to the modern age . so we can understand the meaning of this existence and it’s directins which cover all the worid and the lead us to thiories and suggestion’s help in understand to this direction and the effects between our arts and the external directions.

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Publication Date
Sun Jan 12 2025
Journal Name
Iraqi Journal Of Science
Specification of Actual Evapotranspiration in Iraq by GIS
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     Evapotranspiration (ET) is produced from vegetation transpiration and soil evaporation. The ET measurements must be considered to study water management systems and irrigation (planning, designing and operating). This study is based on USGS (United States Geological Survey) data by the SSEBop (Simplified Surface Energy Balance) model to estimate the total annual amount of ET using ArcGIS software. The ET values were determined for seventeen years from 2003 to 2019. Also, these values for year 2020 were estimated based on the value of the monthly ET for seven months, i.e. until August by summation. The field data of gauge stations spread throughout Iraq for the year 2012 were used to verify the ET values for the s

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Publication Date
Mon Sep 30 2019
Journal Name
College Of Islamic Sciences
consideration In the purposes of faith and destiny
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consideration
In the purposes of faith and destiny

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Publication Date
Tue Feb 14 2023
Journal Name
Journal Of Educational And Psychological Researches
Inclusive education in Saudi Arabia/(Review of Literature)
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Abstract:

Inclusive education has experienced a number of positive educational trends and developments in many different countries, typically by recognising that all students, including those who have special educational needs (SEN), have a right to education. Inclusion of children with SEN in mainstream schools, alongside their peers, has become a major concern for interested educators, professionals and parents in many countries around the world. The reasons for this trend are due to a number of factors such as the increasing attention to the role of education in achieving social justice for pupils with SEN; the right of individuals with SEN to be educated along with their typically developing peers in mainstr

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Publication Date
Sat Apr 15 2023
Journal Name
Iraqi Journal Of Science
Seasonal Variation of Phytoplankton in AL-Diwaniya River
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This study was conducted from January to October 2014, the samples were
collected monthly from four stations in AL-Diwaniya River at AL-Diwaniya city.
Phytoplankton species which are diagnosed during study period are (506) and the
numbers of common types in four sites are (61). Bacillariophyceae is dominate on
other classes and Chlorophyceae, Cyanophyceae, Dinophyceae then Chrysophyceae
and Euglenophyceae. The study shows that there are (150), (144), (118) and (94)
species in the first, second, third and fourth sites. The species that have highs numbers
are (Achnanthes, Cymbella, Nitzschia, Navicula). Other types are dominant in their
existence and number during study period (Cycltella comta, Cylotella Ocellata,

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Publication Date
Sat Mar 01 2008
Journal Name
Al-khwarizmi Engineering Journal
Evaluation of Hydrated Lime Filler in Asphalt Mixtures
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Mineral filler is one of important  materials and affecting on properties and quality of asphalt mixtures .There are different types of mineral filler depended on cost and quality , the matter encourages us to achieve this study to evaluate hydrated lime filler effects on properties of asphalt mixes related with strength and durability. Conventional asphaltic concrete mixtures with Portland cement and soft sandstone fillers and mixtures modified with hydrated lime were evaluated for their fundamental engineering properties as defined by Marshall properties , index of retained strength , indirect tensile strength , permanent deformation characteristics , and fatigue resistance .A typical dense graded mixture employed in construction

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Publication Date
Thu Aug 17 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Application of Kass' Snake in Medical Images Segmentation
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A   snake   is   an   energy-minimizing   spline   guided   by   external

constraint forces and influenced by image forces that pull it toward features such as lines and edges. Snakes are active contour models: they lock onto nearby edges, localizing them accurately. Snakes provide a unified account of a number of visual problems, including detection of edges, lines, and motion tracking. We have used snakes successfully for segmentation, in  which  user-imposed  constraint forces guide the snake near features of interest (anatomical structures). Magnetic Resonance Image (MRI) data set and Ultrasound images are used for our experiments.

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Publication Date
Fri Apr 01 2016
Journal Name
Journal Of Economics And Administrative Sciences
The impact of cultural dimensions in nursing performance
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  Abstract

          The  cultural contrast is considered of the essential subjects in the field of administration of international businesses which have great and effective role for representation in one social system for the individuals have various belongings, and the nursing performance is considered  an essential basic for health care, thus  a discussion for two variables have  done to formulate the intellectual frame for this research which are( the cultural contrast and the nursing performance). depended a questionnaire as a research tool by(90) he/ she nurses of the Iraqis and the arrivals( the

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