Objective: To assess the impact of anxiety and stress during pregnancy upon neonatal outcome Methodology: A descriptive purposive study was used to assess the impact of anxiety and stress during pregnancy upon neonatal outcome. The study was conducted from (22nd \ September \ 2020 to 15th \ February \ 2021). A non-probability sample (purposive sample) was selected from 100 women. Data were collected through an interview with the mother in the counseling clinic, during the third trimester of pregnancy, as well as after childbirth in the labour wards to assess the outcome of pregnancy. Data were analyzed through descriptive statistics (frequency and percentages). Results: The most important thing observed in this study was the negative pregnancy outcome for women suffering from stress there are positive significant relationships among stress with pregnancy outcomes of birth defect, premature baby, and low birth weight at p-value = .028, .001, and .050 respectively there is strong positive significant relationship between anxiety and “premature baby” outcome at p-value= .003, and there is reverse significant relationship between anxiety and “mode of delivery” outcome at p-value= .047. Recommendations: The study recommends according to the results. We suggest that health care providers pay attention to the mental state of pregnant women. Providing training and scheduling support during pregnancy for mothers in order to identify risk factors and achieve skills and knowledge to support mothers, as well as providing a soothing atmosphere to ensure a peaceful environment for pregnant women.