Preferred Language
Articles
/
CRhzopQBVTCNdQwC_R4I
ANTIANGIOGENIC ACTIVITY AND ROS-MEDIATED LUNG CANCER CELL LINE INJURY OF ZERUMBONE
...Show More Authors

Objective: Zerumbone (ZER) is a well-known natural compound that has been reported to have anti-cancer effect. Thus, this study investigated the ZER potential to inhibit Thymidine Phosphorylase (TP) and the ability to trigger Reactive oxygen species (ROS)-mediated cytotoxicity in non-small cell lung cancer, NCI-H460, cell line. Material and Method: The antiangiogenic activity for ZER was evaluated by using the thymidine phosphorylase inhibitory test. Reactive oxygen species (ROS) production was determined via DCFDA dye by using flow cytometry. Result and Discussion: ZER was found to be potent TP inhibitory with the IC50 value of 50.3± 0.31 μg/ml or 230±1.42 µM. NCI-H460 cells upon treatment with ZER produced significant ROS by 55.7%. Consequently, ZER exerts anti-angiogenic properties and modulates ROS production in lung cancer cells, serving as leads for better therapeutic index in cancer drug.

Scopus Crossref
View Publication
Publication Date
Mon Jan 31 2022
Journal Name
Iraqi Journal Of Science
Antibacterial activity of different part of Neem (Azadirchta indica) growing in Sharjah, United Arab Emirates
...Show More Authors

Aqueous and ethanolic extracts of different parts (seeds, leaves, bark) of neem plant (Azadirachta Indica) were screened for antibacterial activaties against five species of bacteria (Staphylococcus aurous, Staphylococcus epidermises, Acinetobacter baumanni, Psedommonas aeruginosa, and Escherishia coli). Different extracts 40-80 mg/L were tested using Ager-well diffusion method. Neem parts potent demonstrated for anti-bacterial activaties against all microorganisms tested. The results showed that neem seeds aqueous and ethanolic, extract have significant effects for all tested bacteria, the maximum inhibition zone by seeds cold aqueous and cold ethanolic extracts were 22 & 13 mm for E. coli and S. epidermidis respectively; while leav

... Show More
View Publication
Publication Date
Sun Oct 22 2023
Journal Name
Iraqi Journal Of Science
Investigating the Influence of the Solar activity on the Electron Density of Mars's Ionospheric Layer
...Show More Authors

The study of Mars's ionosphere was made by investigating the measurements of the electron density (Ne) depending of the variation of the solar activities through different local time, different seasons, and different altitudes. The datasets has been taken from MARSIS on board the Mars Express spacecraft, the investigation for the solar indices and the electron density (Ne) have been made for two period of time depending on the strength of the geomagnetic storms, the first one was taken when the geomagnetic storms was low as in years (1998 & 2005), the data was chosen for three seasons of these years, Winter (December), Summer (June) and Spring (April). The second period was taken for the years (2001 & 2002) when the geomagnetic s

... Show More
View Publication Preview PDF
Publication Date
Sun Jun 07 2009
Journal Name
Baghdad Science Journal
Influence of Brucella melitensis Viability by the Activity of Classical Yoghurt Starter During Milk Fermentation
...Show More Authors

Brucella melitensis isolates were obtained from human infections , and milk which obtained from aborted sheep at Mosul city vicinity . One isolate from each source was used in carrying out this study. Brucella liquid culture was added to sheep milk at 2.5 % for treatments . To first treatment 2 % of yoghurt starter ( Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus salivarius subsp. thermophilus ( 1: 1 ) ) . Second treatment was carried out without addition of yoghurt starter but the pH was lowered using lactic acid in pattern similar to first treatment . Third treatment was similar to the first treatment but contained buffer to alleviate the reduction in pH , which reduced to 6.1 in comparison to 4.9 of the first treatment .

... Show More
View Publication Preview PDF
Crossref
Publication Date
Thu Jun 15 2023
Journal Name
Journal Of Baghdad College Of Dentistry
The Effect of titanium dioxide nanoparticles on the activity of salivary peroxidase in periodontitis patients
...Show More Authors

Background:The technology of nanoparticles has been expanded to many aspects of modern life. Titanium dioxide nanoparticles were of many nanomaterials utilized in biomedical applications. The interactions between nanoparticles and proteins are believed to be the base for the biological effect of the nanoparticles. The oxidation reaction of many substances is catalyzed by oxidizing enzymes called peroxidases. The activity of salivary peroxidase is elevated with periodontal diseases. the aim ofthis study is to examine the action of titanium dioxide nanoparticles on salivary peroxidase activity.Material and method75 participants were enrolled in this study—Periodontitis group with 44 participants and the non-periodontitis group with 31 pa

... Show More
View Publication Preview PDF
Scopus (2)
Scopus Crossref
Publication Date
Tue Mar 14 2023
Journal Name
Iraqi Journal Of Science
Biological Activity of Some Essential Oils on Fifth Instar Nymphs of Ommatissus lybicus (Homoptera: Tropiduchidae)
...Show More Authors

Dubas bug, Ommatissus lybicus (Asche and Wilson) is one of the major sucking pests of date palm. Both nymphs causes severe damage to the leaves by sucking the cell sap . If the damage is severe, it could cause the death of the date palms. The effect of different concentrations of some natural plant essential oils was evaluated on fifth instar nymphs of the insect. The results clearly demonstrated that the tested oils from mint (Mentha piperata), Parsley (Petroselinum sativum), Clove (Syzygium aromaticum), and Eucalyptus (Eucalyptus globules) to evaluate their effect on fecundity of fertile female resulted from these exposed instars nymphs and hatching of these egg. The corrected mortality and numbers of eggs laid, hatching, were studied.

... Show More
View Publication Preview PDF
Publication Date
Wed Dec 01 2010
Journal Name
Al-khwarizmi Engineering Journal
Finite Element Based Solution of Laplace's Equation Applied to Electrical Activity of the Human Body
...Show More Authors

Computer models are used in the study of electrocardiography to provide insight into physiological phenomena that are difficult to measure in the lab or in a clinical environment.

The electrocardiogram is an important tool for the clinician in that it changes characteristically in a number of pathological conditions. Many illnesses can be detected by this measurement. By simulating the electrical activity of the heart one obtains a quantitative relationship between the electrocardiogram and different anomalies.

Because of the inhomogeneous fibrous structure of the heart and the irregular geometries of the body, finite element method is used for studying the electrical properties of the heart.

This work describes t

... Show More
View Publication Preview PDF
Publication Date
Sun Jul 02 2023
Journal Name
Iraqi Journal Of Science
Investigating the Influence of the Solar activity on the Electron Density of Mars's Ionospheric Layer
...Show More Authors

The study of Mars's ionosphere was made by investigating the measurements of the electron density (Ne) depending of the variation of the solar activities through different local time, different seasons, and different altitudes. The datasets has been taken from MARSIS on board the Mars Express spacecraft, the investigation for the solar indices and the electron density (Ne) have been made for two period of time depending on the strength of the geomagnetic storms, the first one was taken when the geomagnetic storms was low as in years (1998 & 2005), the data was chosen for three seasons of these years, Winter (December), Summer (June) and Spring (April). The second period was taken for the years (2001 & 2002) when the geomagnetic s

... Show More
View Publication Preview PDF
Publication Date
Sun Mar 12 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Effect of Lallemantia royleana Seeds Extract in Liver Functions Enzymes Levels and in some Mice Activity Features Treated with Rifadin drug
...Show More Authors

    This study was aimed to investigate the role of crud alcoholic extract of Lallemantia royleana seeds in reducing the hepatotoxicity and side effect of rifadin drug in liver.                      The animals (40 mice) were divided into four groups, the first group was treated with normal saline (0.9%) for 28 days as a control and the second group was treated with rifadin (1.5 mg/kg/day) for 28 days and third group was treated with acoholic extract of Lallemantia royleana seeds (1% w/v) for 28 days, while the forth group was treated with alcoholic extract of seeds alone for 5 days and with alcoholic extract and rifadin for 28 days, so the total period of this group is 33

... Show More
View Publication Preview PDF
Publication Date
Wed Jan 05 2022
Journal Name
Iraqi Journal Of Science
The Inhibition Activity of Silver Nanoparticles Compared with D-Glycin and Imipenem Effect on the Biofilm Formation by Food-origin Salmonella
...Show More Authors

Since decades silver was depended worldwide as a treatment to a lot of diseases
ranging from burn infections, anthrax, and typhoid fever to bacterial conjunctivitis
in stillbirth, but its effectiveness against biofilms is still undetermined. Salmonella is
a major cause of food poisoning outbreaks especially in the third world countries.
Thus, in the present study; the antimicrobial activity of silver nanoparticles (Ag-
NPs) against Salmonella enterica biofilm was examined; their activity was
compared with amino acid; D-Glycin and imipenem antibiotic. The result of the
study revealed that Ag-NPs exhibited considerable antimicrobial property against
Salmonella enterica biofilm where the minimum inhibitory concentrat

... Show More
View Publication Preview PDF
Publication Date
Thu Dec 28 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Synthesis, Characterization and Antibacterial Activity of New Chalcones Derived from New Aldehyde; 4-[5-(4`tolyl)-1,3,4-thiadiazole-2-yl] benzaldehyde
...Show More Authors

 New chalcones of  -{ -  -   -   y  -     - hi di z  e- -y    he y  - -    e e- -  e-    -        - substituted phenyl have been prepared from condensation of  a new of  4-[5-(4`-tolyl)1,3,4-thiadiazole-2-yl] benzaldehyde (which is synthesized by the reaction of  2- amino-5- (4`-tolyl) -1,3,4-thiadiazole and benzaldehyde) with 3- or 4- substituted acetophenones in alkaline medium. The physical, CHNS analysis and spectral data of the synthesized compounds were determined. The biological activity evaluated of new compounds showed that many of these compounds possess antiba

... Show More
View Publication Preview PDF
Crossref (5)
Crossref