Objective: To study the effect of epidural spinal injection over one year in case of spinal stenosis. Methodology: This prospective study included 566 patients with spinal stenosis seen at Al-Kindy Teaching and Al-Sader, Hospitals who were treated by local epidural steroid injection. They were followed up for at least five subsequent visits after seven days, one month, three months, six months, and one year to assess efficacy. Result: Mean age of patients was 49.5 years, with a predominance of females (65%). L4/L5 was the most involved level in the spinal stenosis (70%). Grade II stenosis accounted for (45.4%) of cases. The pairwise comparison revealed that there was significant decrease in proportions of patients with pain in day 3 compared to two weeks (p<0.001). After one year, there was significant increase in patient’s number in comparison to day 3 (p<0.0001). There was a relationship between time and steroid injection that was statistically significant (p<0.05). Conclusion: The patients of spinal stenosis get benefit from epidural steroids injections in early follow-up but the effect decreases over the year.
