To detect the amount of Rifampicin in bulk and medicinal dosage formulations, an accurate, and cost-effective UV spectrophotometric technique has been developed using the area under the peak to estimate the presence of Rifampicin. This range of wavelengths (300–356) nm was chosen. The method showed linearity in the 2-22 μg/mL range, with R2 being 0.9996. The developed method' linearity, detection limit, quantification limit, precision, repeatability, and accuracy were all statistically and experimentally validated. The suggested methodology can be used for routine quality control analysis of Rifampicin in pure form and in capsule dosage form, as demonstrated by the satisfactory recovery percentage results. This study explores the structural, and electronic properties of Rifampicin using Density Functional Theory (DFT) and its interaction with potential biological targets via molecular docking. The DFT analysis, conducted using the B3LYP functional and a suitable basis set, provides detailed insights into the optimized molecular geometry, frontier molecular orbitals (FMOs), and molecular electrostatic potential (MEP) of Rifampicin. The energy gap (∆E= 2.885 eV) exported the stability conditions of Rifampicin. Reduced density gradian analysis (RDG/NCI) was considered to highlight the specific interactions present inside the molecule predicting its stability. Molecular docking studies complement the DFT analysis by identifying Rifampicin's binding affinity (-4.94 kcal/mol) with specific 5F92 target protein. This study evaluates the ADMET properties of Rifampicin to assess its pharmacokinetic and safety profile.
The aim of the research is to provide an analytical study to promote financial inclusion in Iraq by clarifying the opportunities and challenges of the economic and demographic situation in Iraq, studying the structure of the financial system and introducing non-bank financial institutions operating in Iraq, and using the descriptive approach. Analytical in the study of the phenomenon of research, the research reached a number of conclusions, the most prominent of which were:
- Iraqi society is a young society.
- The majority of the population is 70 percent. They live almost in urban areas.
- The coverage of bank branch networks is concentrated in only four provinces, leaving other provinces outside financial
The main aim of the current research is to focus the light on some bacterial contamination on cracked eggshell and egg content plus studying the sensitivity of these bacterial isolates to antibiotics. For this purpose, a total of 50 eggs were collected from the markets in Baghdad city (Iraq) and examined for bacterial isolation from cracked eggshells and from the egg contents. The bacterial isolates were cultured and purified then transferred to a specific media to study its sensitivity against antibiotics. The results revealed that bacteria isolated from both cracked eggshells (46%) and egg contents (44%). The bacteria isolated include E. coli, Staphylococcus, Enterococcus faecalis, Enterobacter and Pseudomonas. The results of antibiotic s
... Show MoreEsterification reaction is most important reaction in biodiesel production. In this study, oleic acid was used as a suggested feedstock to study and simulate production of biodiesel. Batch esterification of oleic acid was carried out at operating conditions; temperature from 40 to 70 °C, ethanol to oleic acid molar ratio from 1/1 to 6/1, H2SO4 as the catalyst 1 and 5% wt of oleic acid, reaction time up to 180 min. The optimum conditions for the esterification reaction were molar ratio of ethanol/oleic acid 6/1, 5%wt H2SO4 relative to oleic acid, 70 °C, 90 min and conversion of oleic 0.92. The activation energy for the suggested model was 26625 J/mole for forward reaction and 42189 J/mole for equilibrium constant. The obtained results s
... Show MoreBackground: The current study aims to identify the morphological description and histological structure of kidney in bird. Morphologically the kidney consist of three lobes represented by the cranial, medial and caudal taking into account the difference in the shape and size of the lobes. According to histology, the kidney is surrounded in a delicate connective tissue capsule. The kidney's primary structural component is the lobule, which is made up of cortical and medullary tissue in each lobule. There are two parts to the kidney medulla and cortex. The cortex is larger than the medulla and has glomeruli, proximal convoluted tubules, and distal convoluted tubules, whereas the medulla has thin and thick segments o
... Show MoreThe current study aimed to detect artificial fraud in chemical additives (formalin, hydrogen peroxide) and to detect thickeners (starch) in imported and local dairy products and to determine their suitability for human consumption due to the high demand for their consumption by members of society, 20 samples of products were collected The local and imported milk in the Iraqi markets of the city of Baghdad consisted of 10 samples of yoghurt and 10 samples of cream. The tests were carried out, which were the detection of chemicals and additive thickeners such as formalin, hydrogen peroxide and starch, respectively, as well as the examination of the microbial load, which included the detection of colon bacteria, yeasts and molds, and the resul
... Show MoreIt is more beneficial science and created and the highest honor is the Koran Sciences, God has honored research in this fun science, came this research that shed the light on the radical incision, and Naughty derivatives as contained in the Koran, and illustrate the diversity of Saghma morphological, and fork them from derivatives what it entailed connotations, as well as the evacuation of cryptic in some of these verses from the biological secrets take minds newly exposed Anitrjt science under the name of scientific miracles.
The research methodology is revenue verse which included the word, and revenue lexical meaning and its meaning in the context of the Qur'an, and reflect the views of the commentators of the verse, and then the r
Through this research, We have tried to evaluate the health programs and their effectiveness in improving the health situation through a study of the health institutions reality in Baghdad to identify the main reasons that affect the increase in maternal mortality by using two regression models, "Poisson's Regression Model" and "Hierarchical Poisson's Regression Model". And the study of that indicator (deaths) was through a comparison between the estimation methods of the used models. The "Maximum Likelihood" method was used to estimate the "Poisson's Regression Model"; whereas the "Full Maximum Likelihood" method were used for the "Hierarchical Poisson's Regression Model
... Show MoreGiving advice refers to an attempt by the speaker to express what the addressee should do in a particular situation or what is good for him/her. It is also a feature of making social relations and communications move smoothly and become stronger. The current study aims to investigate the strategies of the speech act of advice by old females and males for the younger generation in written signs. Comparison is made between old females and males regarding their pragmatic use of advice and the way they are manifested in expressing gender identity differences. The sample of the study consists of (30) written signs of advice divided equally between the two gender groups. Hinkel’s (1997) classification of the strategies for perceiving th
... Show MoreA dust storm in Iraq is a climatic phenomenon common in arid and semi-arid regions . The frequency of the occurrence has increased drastically in the last decade and it is increasing continuously .Baghdad city like the rest of Iraq is suffering from the significant increase in dust storms . In this research , the study of the phenomenon of dust storms for all types (Suspended dust , rising dust , dust storm) , and its relationship with some climate variables (Temperature , rainfall ,wind speed) .The statement of the impact of climate change on this phenomenon to Baghdad station for the period (1981 – 2012) . Time series has been addressing the phenomenon of storms and cli
... Show MoreKE Sharquie, AA Noaimi, AH Muhammad Ali, 2008 - Cited by 3