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Attenuation of Staphylococcal enterotoxin-B (SEB)-induced lung injury (ALI) by resveratrol results from miR-193a down-regulation and alterations in metabolic profile
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Abstract<p>Resveratrol, (RES), a phytoalexin, is well-known for its anti-inflammatory and anti-oxidant properties. SEB, a superantigen, is known to trigger ALI and cause mortality. In the current study, we tested the effect of RES in a dual-dose model of SEB exposure that triggers ALI and causes 100% mortality in C3H/HeJ-mice. The data revealed RES attenuated SEB-induced ALI and prevented mortality. Forty eight hours post-SEB exposure, lung-infiltrating mononuclear cells were tested for microRNA expression profile to determine the epigenetic regulation by resveratrol. SEB-activated splenocytes were pre-treated with 50 μM of RES or vehicle for metabolic profile analysis by measuring oxygen consumption rate (OCR) and extracellular acidification rate (ECAR). We also noted significant decline in miR-193a in the lungs of RES-treated SEB group, which targeted and caused an increase in TGFβ2 and TGFβR3, potent inhibitors of T-cell proliferation, by using RT-PCR and validation by transfection studies. RES-induced downregulation of miR-193a also influenced the activity of mechanistic target of rapamycin (mTOR) as well as pyruvate kinase muscle isozyme2 (PKM2) genes, and caused RES-treated SEB-activated T cells to be quiescent metabolically in comparison to the energetic vehicle-treated SEB-activated T cells. Together, RES caused inhibition in the proliferation of SEB-activated T-cells by alterations in miR expression and metabolic profiles. (Supported by NIH grants P01AT003961, R01AT006888, R01ES019313, R01MH094755, P20GM103641 and R01AI129788).</p>
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Publication Date
Sat Sep 30 2023
Journal Name
Iraqi Journal Of Science
Further Results on Graceful Antimagic Graphs
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     Graceful labeling of a graph  with q edges is assigned the labels for its vertices by some integers from the set such that no two vertices received the same label, where each edge is assigned the absolute value of the difference between the labels of its end vertices and the resulting edge labeling running from 1 to  inclusive. An edge labeling of a graph G is called vertex anntimagic, if all vertex weights are pairwise distinct, where the vertex weight of a vertex under an edge labeling is the sum of the label of all edges incident with that vertex.  In this paper, we address the problem of finding graceful antimagic labelin for split of the star graph ,  graph,  graph, jellyfish graph , Dragon graph , ki

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Publication Date
Sun Sep 04 2016
Journal Name
Baghdad Science Journal
Some Results on Weak Essential Submodules
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Throughout this paper R represents commutative ring with identity and M is a unitary left R-module. The purpose of this paper is to investigate some new results (up to our knowledge) on the concept of weak essential submodules which introduced by Muna A. Ahmed, where a submodule N of an R-module M is called weak essential, if N ? P ? (0) for each nonzero semiprime submodule P of M. In this paper we rewrite this definition in another formula. Some new definitions are introduced and various properties of weak essential submodules are considered.

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Publication Date
Sat Sep 23 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Some Results on Fibrewise Topological Spaces
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In this paper we define and study new concepts of functions on fibrewise  topological spaces  over  B namely,  fibrewise  weakly  (resp., closure, strongly) continuoac; funttions which are analogous of weakly

(resp., closure,   strongly)   continuous  functions   and  the  main  result is   : Let  <p       : XY  be a fibrewise  closure  (resp.,  weakly,  closure, strongly,  strongly) continuous function,  where  Y  is fibrewise topological  space  over  B and  X  is  a  fibrewise set  which  has  the

in

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Publication Date
Thu Apr 20 2023
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Some Results on the Divisible Hyperrings
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A class of hyperrings known as divisible hyperrings will be studied in this paper. It will be presented as each element in this hyperring is a divisible element. Also shows the relationship between the Jacobsen Radical, and the set of invertible elements and gets some results, and linked these results with the divisible hyperring. After going through the concept of divisible hypermodule that presented 2017, later in 2022, the concept of the divisible hyperring will be related to the concept of division hyperring, where each division hyperring is divisible and the converse is achieved under conditions that will be explained in the theorem 3.14. At the end of this paper, it will be clear that the goal of this paper is to study the concept

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Publication Date
Sun Sep 04 2016
Journal Name
Baghdad Science Journal
Some Results on Weak Essential Submodules
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Throughout this paper R represents commutative ring with identity and M is a unitary left R-module. The purpose of this paper is to investigate some new results (up to our knowledge) on the concept of weak essential submodules which introduced by Muna A. Ahmed, where a submodule N of an R-module M is called weak essential, if N ? P ? (0) for each nonzero semiprime submodule P of M. In this paper we rewrite this definition in another formula. Some new definitions are introduced and various properties of weak essential submodules are considered.

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Publication Date
Mon Aug 07 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Some Results on Semi-preopen Sets
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      The definition of semi-preopen sets were first introduced by "Andrijevic" as were is defined by :Let (X ,  ) be a topological space, and let  A ⊆,    then A is called semi-preopen set if ⊆∘ .        In this paper, we study the properties of semi-preopen sets but by another  definition which is equivalent to the first definition and we also study the relationships among it and (open, α-open, preopen and semi-p-open )sets.

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Publication Date
Wed Mar 01 2023
Journal Name
Baghdad Science Journal
Some New Results on Lucky Labeling
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Czerwi’nski et al. introduced Lucky labeling in 2009 and Akbari et al and A.Nellai Murugan et al studied it further. Czerwi’nski defined Lucky Number of graph as follows: A labeling of vertices of a graph G is called a Lucky labeling if  for every pair of adjacent vertices u and v in G where . A graph G may admit any number of lucky labelings. The least integer k for which a graph G has a lucky labeling from the set 1, 2, k is the lucky number of G denoted by η(G). This paper aims to determine the lucky number of Complete graph Kn, Complete bipartite graph Km,n and Complete tripartite graph Kl,m,n. It has also been studied how the lucky number changes whi

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Publication Date
Sun Apr 30 2023
Journal Name
Iraqi Journal Of Science
Some Results on Essentially Quasi-DedekindModules
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In this paper we give many connections between essentially quasi-Dedekind (quasi-
Dedekind) modules and other modules such that Baer modules, retractable modules,
essentially retractable modules, compressible modules and essentially compressible
modules where an R-module M is called essentially quasi-Dedekind (resp. quasi-
Dedekind) if, Hom(M N ,M )  0 for all N ≤e M (resp. N ≤ M). Equivalently, a
module M is essentially quasi-Dedekind (resp. quasi-Dedekind) if, for each
f End (M) R  , Kerf ≤ e M implies f = 0 (resp. f  0 implies ker f  0 ).

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Publication Date
Thu Jul 20 2023
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Some Results on Nano Perfect Mappings
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The structure of this paper includes an introduction to the definition of the nano topological space, which was defined by M. L. Thivagar, who defined the lower approximation of G and the upper approximation of G, as well as defined the boundary region of G and some other important definitions that were mentioned in this paper with giving some theories on this subject. Some examples of defining nano perfect mappings are presented along with some basic theories. Also, some basic definitions were presented that form the focus of this paper, including the definition of nano  pseudometrizable space, the definition of nano compactly generated space, and the definition of completely nano para-compact. In this paper, we presented images of nan

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Publication Date
Mon Jun 01 2020
Journal Name
Iraqi Journal Of Physics
Influence of Sn doping ratio on the structural and optical properties of CdO films prepared by laser induced plasma
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In this work, we study the effect of doping Sn on the structural and optical properties of pure cadmium oxide films at different concentrations of Tin (Sn) (X=0.1,0.3 and 0.5) .The films prepared by using the laser-induced plasma at wavelength of laser 1064 nm and duration 9 ns under pressure reached to 2.5×10-2 mbar. The results of X-ray diffraction tests showed that the all prepared films  are polycrystalline. As for the topography of the films surface, it was measured using AFM , where the results showed that the grain size increases with an increase in the percentage of doping  in addition to an increase in the average roughness. The optical properties of all films have also been studied through the absorbance s

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