The goal of this study was to investigate the protein peroxidation role by measuring serum levels of advanced oxidation protein products (AOPP) in type 2 diabetic patients with or without retinopathy and comparing them to controls to see if circulating AOPP levels can be used as a detection biomarker for DR. And see which of the two widely used antidiabetic treatment groups had the most impact on this oxidative stress marker. The groups were divided into two subgroups: 1) 70 type 2 diabetic patients (36 male, 34 female), 35 with diabetic retinopathy (DR) and 35 with no evidence of DR, and 2) non-diabetic controls (11 male, 9 female) were chosen from Ibn AL-Haitham Hospital for Ophthalmology and a Specialized Center for Endocrinology and Diabetes. AOPP levels were significantly higher in diabetic patients with (12.5±5.6 ng/ml) or without DR (5.1±4 ng/ml) when compared to those of controls (1.45 0.8 ng/ml) (p<0.05). AOPP levels were higher in the late stage of DR compared to the early stage(14 3.15 ng/ml ) and ( 10 2.13 ng/ml) respectively so. Furthermore, Dipeptidyl peptidase-4 inhibitors (DPP-4 inhibitors) cause a better reduction in AOPP levels compared to Sulfonylureas (SUs) in the NDR group. Increased protein oxidation may involve in the pathogenesis and severity of DR and the serum AOPP levels have the prospect to become a marker for the diagnosis of DR. DPP-4 inhibitors were better in slowing the progression of the disease compared to SUs.
لقد كان الألفون جزءاً من اللوحة الفونيميّة، وهو جزء صوتيّ لا يُغيّر المعنى، مع أنّه تغيّر صوتيّ فونيميّ، له أنواعه المتمثّلة بالهمس والجهر، والنّبر، والاختلاس، والإخفاء، والإشمام، والإقلاب، والتّماس، والقلب، وهذه الأنواع كانت مؤشّرات تنغيميّة صوتيّة نالت حظّاً وافراً لدى باحثي الأصوات وعلماء التّجويد، وكان لها شروطها ومواقعها وأثرها في المخاطِب والمخاطَب، لأنّ كلّ صوت يخرج من متكلّم ليصل إلى سامع يؤثر ب
... Show MoreCompanies compete greatly with each other today, so they need to focus on innovation to develop their products and make them competitive. Lean product development is the ideal way to develop product, foster innovation, maximize value, and reduce time. Set-Based Concurrent Engineering (SBCE) is an approved lean product improvement mechanism that builds on the creation of a number of alternative designs at the subsystem level. These designs are simultaneously improved and tested, and the weaker choices are removed gradually until the optimum solution is reached finally. SBCE implementations have been extensively performed in the automotive industry and there are a few case studies in the aerospace industry. This research describe the use o
... Show Moreتناول هذا البحث الدور الحيوي الذي تؤديه المراكز البحثية في دعم القضايا الاجتماعية، مع التركيز على مركز دراسات المرأة في جامعة بغداد كنموذج تطبيقي. يوضح الباحث أن هذه المراكز لا تقتصر على إنتاج المعرفة النظرية، بل تسهم بشكل مباشر في معالجة التحديات المجتمعية، من خلال تقديم رؤى تحليلية ومقترحات عملية لصناع القرار. كما ويسلط الضوء على مساهمة مركز دراسات المرأة في تعزيز المشاركة السياسية للمرأة العراقية، خاصة
... Show Moreالسياسة الداخلية لعراق ما بعد الانتخابات 2010 دراسة في الثوابت والمتغيرات
مقدمة introduction تُعد تقنيات الذكاء الاصطناعي قاطرة الثورة الصناعية الرابعة، إذ تجاوزت حدود البرمجة التقليدية إلى التعلم العميق الذي مكّن الآلات من تنفيذ مهام بشرية معقدة، مثل تحليل الصور، ومعالجة اللغات الطبيعية، وإنتاج محتوى إبداعي. فأصبحت التطبيقات تعتمد على الذكاء الاصطناعي في جميع القطاعات، من الرعاية الصحية إلى التعليم، ومن الأمن إلى الفنون. ومع ذلك، مثلما أن كل تقدم يحمل في طياته إمكانات هائلة، فإنه يج
... Show MoreAl comentar un texto literario no se llega solamente mediante el estudio de su Historia. Ese estudio sería vano, se convertiría en una simple memorización de datos, creo yo.
Comentar un texto supone comprobar las características generales de un movimiento, estilo de un autor... en otras palabras comprender con profundidad el texto literario en s
The substantial key to initiate an explicit statistical formula for a physically specified continua is to consider a derivative expression, in order to identify the definitive configuration of the continua itself. Moreover, this statistical formula is to reflect the whole distribution of the formula of which the considered continua is the most likely to be dependent. However, a somewhat mathematically and physically tedious path to arrive at the required statistical formula is needed. The procedure in the present research is to establish, modify, and implement an optimized amalgamation between Airy stress function for elastically-deformed media and the multi-canonical joint probability density functions for multivariate distribution complet
... Show MoreA new concrete rheometer is introduced including its innovation, actual design, working rules,
calibration, and reliability. A modified design of Tattersall two-point device is created. Some of
components are purchased from local and foreign markets, while other components and the
manufacturing process are locally fabricated. The matching viscosity method of determining the mixer
viscometer constants is demonstrated and followed to relate torque and rotational speed to yield stress
and viscosity (Bingham parameters). The calibration procedures and its calculation are explained.
Water is used as a Newtonian fluid, while; cement paste (cement + water) with w/c ratio equal to
(0.442) is used as a non-Newtonian fluid. Th
This study examines the vibrations produced by hydropower operations to improve embankment dam safety. This study consists of two parts: In the first part, ANSYS-CFX was used to generate a three-dimensional (3-D) finite volume (FV) model to simulate a vertical Francis turbine unit in the Mosul hydropower plant. The pressure pattern result of the turbine model was transformed into the dam body to show how the turbine unit's operation affects the dam's stability. The upstream reservoir conditions, various flow rates, and fully open inlet gates were considered. In the second part of this study, a 3-D FE Mosul dam model was simulated using an ANSYS program. The operational turbine model's water pressure pattern is conveyed t
... Show MoreDie Zusammenfassung :
In der Forschung „ Die Wirkungen der Nachkriegliteratur „ findet man einen Überblick über die Wirkungen der Literatur im Allgemeinen und besonders über die Wirkungen der Nachkriegliteratur in Deutschland. Das Kurzgeschichte „ das Brot“ von Wolfgang Borchert „ wird in dieser Forschung als Beispiel analysiuert, weil sie die Nachteile des Kriegs und ihre Wirkungen auf die Familienbeziehungen behandelt. Die Hauptfiguren der Kurzgeschichte sind ein alter Mann und seine Frau. Der Schriftsteller bestimmt die Rolle der Frauen in Deutschland. Die Frau in dieser Geschichte ist stärker als ihren Mann , denn er war lügner und schwach.
Post-war Literature has an e
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