The goal of this study was to investigate the protein peroxidation role by measuring serum levels of advanced oxidation protein products (AOPP) in type 2 diabetic patients with or without retinopathy and comparing them to controls to see if circulating AOPP levels can be used as a detection biomarker for DR. And see which of the two widely used antidiabetic treatment groups had the most impact on this oxidative stress marker. The groups were divided into two subgroups: 1) 70 type 2 diabetic patients (36 male, 34 female), 35 with diabetic retinopathy (DR) and 35 with no evidence of DR, and 2) non-diabetic controls (11 male, 9 female) were chosen from Ibn AL-Haitham Hospital for Ophthalmology and a Specialized Center for Endocrinology and Diabetes. AOPP levels were significantly higher in diabetic patients with (12.5±5.6 ng/ml) or without DR (5.1±4 ng/ml) when compared to those of controls (1.45 0.8 ng/ml) (p<0.05). AOPP levels were higher in the late stage of DR compared to the early stage(14 3.15 ng/ml ) and ( 10 2.13 ng/ml) respectively so. Furthermore, Dipeptidyl peptidase-4 inhibitors (DPP-4 inhibitors) cause a better reduction in AOPP levels compared to Sulfonylureas (SUs) in the NDR group. Increased protein oxidation may involve in the pathogenesis and severity of DR and the serum AOPP levels have the prospect to become a marker for the diagnosis of DR. DPP-4 inhibitors were better in slowing the progression of the disease compared to SUs.
في ظل العولمه و التقدم التكنولوجي الهائل و الصراعات الاقتصاديه و تنافس السوق في شتي المجالات اصبح يثق علي عاتق الاداره علي جميع المستويات المؤسسيه و جميع تخصصاتها الحمل الاكبر في مواكبه تلك التغيرات ، وحيث ان نظام التعليم ينتج لنا اجيال يجب ان تواكب تلك التغيرات لتتماشي مع متطلبات السوق الحالي و المستقبلي و نظام التعليم يعد احد اهم الركائز التي تستند عليه الموارد البشريه بالنسبه للدوله و اي مؤسسه ، و من هنا ب
... Show Moreضمانات الاستثمار في حقول الغاز
شغلت الإشاعة حيزا مهما من اهتمام العلوم الاجتماعية وكانت مادة بحث في علم النفس الفردي وعلم النفس الاجتماعي وعلم الاجتماع والسياسة. ويأتي هذا الاهتمام الكبير والمتواصل بالإشاعة لآثارها الخطيرة على حياة الأفراد والمجتمعات في أوقات السلم والحرب.
the regional and spatial dimension of development planning must be taken as a point of departure to the mutual of the spatial structure of the economy , development strategy and policies applied 'therein such as the location principles and regional development coordination of the territorial problems with the national development planning and timing of regional vis-a-vis national development plan_. Certain balance and integration is of sound necessity' between national _regional and local development objectives through which the national development strategy should have to represent the guidelines of the local development aspirations and goals. The economic development exerts an impact on the spatial evolution, being itself subje
... Show Moreان فلسفة ما بعد الحداثة ادخلت تغيرات عدة في عالم الحداثة
تحديدات مفاهيمية في التحليل السياسي
يتناول البحث جزئية من جزئيات عقد الفيديك
This research psychological construction in the Koran, and the researcher with an overview of the importance of and the need HSCode Elbe.
Built Koran souls on faith and piety , the more you build good was the commitment approach Koran evident , because the Koran built for these souls path will not Tdilh never astronomer can occur amendment or a change in the character of a man in his behavior it is necessary to modify or change his ideas and trends as the human behavior is influenced by a major impact his ideas and trends , the Inn Koran to change people's ideas and attitudes and behavior and to guide them and change what they are in it from going astray and ignorance and directing them to what it Slaham and well-being , and prov
... Show More That it is essential to be for us to recognize is that the phenomenon of poverty are addressed most of the doors of Arab countries in general and Iraq in particular, with the contrast between Qatar and another, and that the deteriorating situation of developing countries it is clear that poor people are victims of exploitation and inequality.
That dealing with the phenomenon of poverty should be more present in mind, especially since the Arab world that enters the era of so-called globalization, as more people poor, and the increase of the utilization of materials Arab interests abroad under the competition is unequal and the impoverishment of deliberate environmental and resource Arab