Doses for most drugs are determined from population-level information, resulting in a standard ?one-size-fits-all’ dose range for all individuals. This review explores how doses can be personalised through the use of the individuals’ pharmacokinetic (PK)-pharmacodynamic (PD) profile, its particular application in children, and therapy areas where such approaches have made inroads.

Abstract. Silver, Indium Selenium thin film with a thickness (5001±30) nm, deposited by thermal evaporation methods at RT and annealing3temperature (Ta=400, 500 and 600) K on a substrate of glass to study structural and optical properties of thin films and on p-Si wafer to fabricate the AgInSe2/p-Si heterojunction solar cell. XRD analysis shows that the AgInSe2 (AIS) deposited film at RT and annealing3temperature (Ta=400, 500 and 600) K have polycrystalline structure. The average grain size has been estimated from AFM images. The energy gap was estimated from the optical transmittance using a spectrometer type (UV.-Visible 1800 spectra photometer). From I-V characterization , the photovoltaic parameters such as, open-circuit voltage, short

The present study refers to a ready-made three components epoxy based paint made by the Modern Paints Industries Company (Al-Za'farania, Baghdad) subjected to several tests in order to improve its specifications by optimizing the application conditions. The paint components are under the trade names: Resin (D-5547), Hardener (H-1457) and Thinner (P-851). The paint is used for painting drinking water reservoirs from inside.

A flexible pavement structure usually comprises more than one asphalt layer, with varying thicknesses and properties, in order to carry the traffic smoothly and safely. It is easy to characterize each asphalt layer with different tests to give a full description of that layer; however, the performance of the whole; asphalt structure needs to be properly understood. Typically, pavement analysis is carried out using multi-layer linear elastic assumptions, via equations and computer programs such as KENPAVE, BISAR, etc. These types of analysis give the response parameters including stress, strain, and deflection at any point under the wheel load. This paper aims to estimate the equivalent Resilient Modulus (MR) of the asphalt concrete

The local asphalt concrete fracture properties represented by the fracture energy, J-integral, and stress intensity factor are calculated from the results of the three point bending beam test made for pre notches beams specimens with deformation rate of 1.27 ^mm/min. The results revealed that the stress intensity factor has increased by more than 40% when decreasing the testing temperature 10˚C and increasing the notch depth from 5 to 30^mm. The change of asphalt type and content have a limited effect of less than 6%.

All - Mighty Allah is beautiful and loves beauty and  Man is the only living  that is given by  the gift of Almighty Allah  the ability to awareness of beauty and the taste of  everything which recognized by him  around all aspects of life.

So the  children have more  ability  than others towards  feeling the  sense of beauty and the distinction between the beautiful and the ugly understanding , as they are attracted to the beauty , so we  should promote and encourage  their sense of beauty in future  the beauty in behavior , in psychology and in the community, as well.

This is definitely be done through all of

Flutter is a phenomenon resulting from the interaction between aerodynamic and structural dynamic forces and may lead to a destructive instability. The aerodynamic forces on an oscillating airfoil combination of two independent degrees of freedom have been determined. The problem resolves itself into the solution of certain definite integrals, which have been identified as Theodorsen functions. The theory, being based on potential flow and the Kutta condition, is fundamentally equivalent to the conventional wing-ection theory relating to the steady case. The mechanism of aerodynamic instability has been analyzed in detail. An exact solution, involving potential flow and the adoption of the Kutta condition, has been analyzed in detail. Th